Detailed information NTG0599625

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: K6975_RS04345
• Genome accession: NZ_CP082197
• Coordinates: 878568..879410 (+)
• Length: 280 a.a.
• NCBI ID: WP_012775129.1
• Uniprot ID: -
• Organism: Streptococcus suis strain Transconjugant cSS389
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 873568..884410

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
K6975_RS04315 (K6975_04315)	-	874297..874947 (-)	651	WP_002936498.1	hemolysin III family protein	-
K6975_RS04320 (K6975_04320)	-	874937..875488 (-)	552	WP_011922482.1	DUF1836 domain-containing protein	-
K6975_RS04325 (K6975_04325)	-	875596..877254 (-)	1659	WP_011922481.1	FAD-dependent oxidoreductase	-
K6975_RS04330 (K6975_04330)	-	877251..877574 (-)	324	WP_012775130.1	rhodanese-like domain-containing protein	-
K6975_RS04335 (K6975_04335)	-	877681..877941 (+)	261	WP_009909865.1	metal-sensitive transcriptional regulator	-
K6975_RS04340 (K6975_04340)	-	877952..878509 (+)	558	WP_011922479.1	sugar O-acetyltransferase	-
K6975_RS04345 (K6975_04345)	dprA	878568..879410 (+)	843	WP_012775129.1	DNA-processing protein DprA	Machinery gene
K6975_RS04350 (K6975_04350)	topA	879503..881596 (+)	2094	WP_012775128.1	type I DNA topoisomerase	-
K6975_RS04355 (K6975_04355)	rplJ	882173..882667 (+)	495	WP_002936486.1	50S ribosomal protein L10	-
K6975_RS04360 (K6975_04360)	rplL	882733..883098 (+)	366	WP_002936483.1	50S ribosomal protein L7/L12	-
K6975_RS04365 (K6975_04365)	-	883223..883972 (+)	750	WP_011922420.1	HAD family hydrolase	-

Sequence

Protein

• Length: 280 a.a.
• Molecular weight: 31246.14 Da
• Isoelectric Point: 8.4451

>NTDB_id=599625 K6975_RS04345 WP_012775129.1 878568..879410(+) (dprA) [Streptococcus suis strain Transconjugant cSS389]
MNNFELFKWKKAGLTNLNVNKVLAYQEKHGKKLTLRNVAVVSECKNPVLFMENYKNLDTKACREEFNKYPSFSILDDIYP
LALKQIYNPPVLLFYQGDLELLEKLKLAVVGTRNASKNGIQSVQKIIKELSNRFVIVSGLARGIDTAAHIASLKNGGQTI
AVIGTGLDNIYPKENKDLQTYIGKHHLVLTEYEAGAQPLKYHFPERNRIIAGLVEGLVVCEAKMRSGSLITCERALEEGR
EVYAIPGSIMDGKSDGCHHLIQEGAKCVTSGLDIISEYQF

Nucleotide

• Length: 843 bp

>NTDB_id=599625 K6975_RS04345 WP_012775129.1 878568..879410(+) (dprA) [Streptococcus suis strain Transconjugant cSS389]
ATGAATAATTTTGAATTGTTTAAATGGAAAAAAGCAGGTTTGACCAATCTTAATGTGAATAAAGTTTTGGCCTATCAAGA
AAAACACGGTAAAAAATTGACCTTGCGAAATGTCGCTGTAGTGTCTGAATGTAAAAATCCAGTGCTATTTATGGAAAATT
ATAAGAATCTAGATACAAAAGCCTGTCGCGAGGAATTTAATAAGTATCCATCATTTTCAATTTTAGATGACATCTATCCT
TTGGCGCTCAAACAGATTTACAATCCACCTGTACTTTTGTTTTATCAAGGGGATTTAGAATTGCTAGAAAAATTAAAGCT
GGCAGTTGTTGGTACACGAAATGCCAGTAAAAATGGTATCCAATCTGTTCAGAAAATTATCAAGGAATTGAGCAATCGTT
TTGTCATTGTTAGTGGTTTGGCAAGAGGAATTGATACAGCTGCCCACATCGCCAGTTTGAAAAATGGAGGCCAAACCATT
GCTGTAATCGGAACAGGTTTAGATAATATTTATCCAAAAGAAAATAAAGATTTGCAGACCTATATTGGAAAACACCATTT
GGTGCTGACAGAGTATGAAGCTGGTGCTCAGCCACTCAAATACCATTTTCCAGAACGCAATCGCATTATAGCTGGTTTGG
TGGAAGGATTGGTAGTCTGCGAGGCAAAAATGCGGTCTGGCAGCTTGATTACTTGTGAACGTGCCTTGGAAGAAGGAAGA
GAAGTCTATGCTATTCCAGGTTCCATTATGGACGGAAAATCAGATGGTTGTCATCATTTGATTCAAGAGGGAGCAAAGTG
CGTTACATCAGGATTGGACATCATTTCTGAGTATCAATTTTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (73-269)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-61)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	70	100	0.7
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	63.571	100	0.636
dprA/cilB/dalA	Streptococcus pneumoniae D39	63.571	100	0.636
dprA/cilB/dalA	Streptococcus pneumoniae R6	63.571	100	0.636
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	63.571	100	0.636
dprA/cilB/dalA	Streptococcus mitis SK321	63.571	100	0.636
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	63.571	100	0.636
dprA	Lactococcus lactis subsp. cremoris KW2	60	100	0.6
dprA	Legionella pneumophila strain ERS1305867	42.105	88.214	0.371
dprA	Bacillus subtilis subsp. subtilis str. 168	50.746	71.786	0.364