Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   MSA_RS05385 Genome accession   NC_021486
Coordinates   998292..998972 (-) Length   226 a.a.
NCBI ID   WP_000590620.1    Uniprot ID   A0AAV3JNX7
Organism   Streptococcus agalactiae ILRI005     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 993292..1003972
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MSA_RS05360 (MSA_11010) - 993475..994248 (-) 774 WP_016480737.1 DUF3307 domain-containing protein -
  MSA_RS05365 (MSA_11020) - 994238..994924 (-) 687 WP_016480738.1 SatD family protein -
  MSA_RS05370 (MSA_11030) ffh 994991..996556 (-) 1566 WP_000863591.1 signal recognition particle protein -
  MSA_RS05375 (MSA_11040) - 996574..996906 (-) 333 WP_000402075.1 putative DNA-binding protein -
  MSA_RS05380 (MSA_11050) ciaH 996995..998308 (-) 1314 WP_000042584.1 HAMP domain-containing sensor histidine kinase Regulator
  MSA_RS05385 (MSA_11060) ciaR 998292..998972 (-) 681 WP_000590620.1 response regulator transcription factor Regulator
  MSA_RS05390 (MSA_11070) - 999134..1001689 (-) 2556 WP_016480739.1 M1 family metallopeptidase -
  MSA_RS05395 (MSA_11080) phoU 1001835..1002488 (-) 654 WP_000946330.1 phosphate signaling complex protein PhoU -
  MSA_RS05400 (MSA_11090) pstB 1002522..1003280 (-) 759 WP_016480740.1 phosphate ABC transporter ATP-binding protein PstB -

Sequence

Protein


Download         Length: 226 a.a.        Molecular weight: 25852.63 Da        Isoelectric Point: 4.2507

>NTDB_id=59125 MSA_RS05385 WP_000590620.1 998292..998972(-) (ciaR) [Streptococcus agalactiae ILRI005]
MIKILLIEDDLSLSNSVFDFLDDFADVMQIFDGEEGLYEAESGVYDLILLDLMLPEKNGFQVLKELREKGITTPVLIMTA
KESIDDKGQGFDLGADDYLTKPFYLEELKMRIQALLKRSGKFNDNSLIYGDIRVDMSTNSTFVNQTEVELLGKEFDLLVY
FLQNQNVILPKSQIFDRIWGFDSDTTISVVEVYVSKVRKKLKGTLFSENLQTLRSVGYILKHVETD

Nucleotide


Download         Length: 681 bp        

>NTDB_id=59125 MSA_RS05385 WP_000590620.1 998292..998972(-) (ciaR) [Streptococcus agalactiae ILRI005]
ATGATAAAAATTTTATTAATTGAAGATGACTTGAGTCTTTCCAATTCCGTTTTTGATTTCCTTGATGACTTTGCCGATGT
CATGCAAATTTTTGATGGAGAAGAGGGTCTTTACGAAGCCGAAAGTGGAGTCTATGATCTGATTCTTCTAGATCTCATGT
TACCTGAAAAAAACGGCTTCCAAGTGTTGAAAGAGCTACGTGAAAAAGGTATTACAACCCCTGTATTAATAATGACCGCT
AAAGAAAGCATTGATGATAAGGGACAAGGTTTCGACTTAGGTGCTGATGATTATCTAACAAAACCTTTTTACCTAGAAGA
ACTAAAAATGCGAATTCAGGCTCTTTTAAAGCGTTCTGGAAAATTTAATGATAACAGCCTAATTTATGGTGATATTCGCG
TAGACATGTCTACTAACTCAACCTTTGTTAATCAAACAGAAGTTGAGCTCTTAGGTAAAGAGTTTGATCTTTTAGTCTAT
TTCCTTCAAAATCAAAATGTTATCTTACCGAAATCTCAAATCTTTGATCGTATTTGGGGATTTGATAGTGATACAACGAT
TTCAGTTGTAGAAGTCTATGTCTCTAAGGTTCGGAAAAAATTAAAAGGAACACTTTTTTCAGAAAACCTTCAAACTTTGC
GTAGTGTAGGATATATTTTAAAGCATGTCGAAACCGATTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(146-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae TIGR4

88.393

99.115

0.876
  ciaR Streptococcus pneumoniae D39

88.393

99.115

0.876
  ciaR Streptococcus pneumoniae R6

88.393

99.115

0.876
  ciaR Streptococcus pneumoniae Rx1

88.393

99.115

0.876
  ciaR Streptococcus mutans UA159

88.688

97.788

0.867
  vicR Streptococcus mutans UA159

35.193

100

0.363
  covR Lactococcus lactis subsp. lactis strain DGCC12653

36.607

99.115

0.363

Multiple sequence alignment