Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   MSA_RS05380 Genome accession   NC_021486
Coordinates   996995..998308 (-) Length   437 a.a.
NCBI ID   WP_000042584.1    Uniprot ID   -
Organism   Streptococcus agalactiae ILRI005     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 991995..1003308
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MSA_RS05355 (MSA_11000) - 992225..993442 (+) 1218 Protein_967 peptide ABC transporter substrate-binding protein -
  MSA_RS05360 (MSA_11010) - 993475..994248 (-) 774 WP_016480737.1 DUF3307 domain-containing protein -
  MSA_RS05365 (MSA_11020) - 994238..994924 (-) 687 WP_016480738.1 SatD family protein -
  MSA_RS05370 (MSA_11030) ffh 994991..996556 (-) 1566 WP_000863591.1 signal recognition particle protein -
  MSA_RS05375 (MSA_11040) - 996574..996906 (-) 333 WP_000402075.1 putative DNA-binding protein -
  MSA_RS05380 (MSA_11050) ciaH 996995..998308 (-) 1314 WP_000042584.1 HAMP domain-containing sensor histidine kinase Regulator
  MSA_RS05385 (MSA_11060) ciaR 998292..998972 (-) 681 WP_000590620.1 response regulator transcription factor Regulator
  MSA_RS05390 (MSA_11070) - 999134..1001689 (-) 2556 WP_016480739.1 M1 family metallopeptidase -
  MSA_RS05395 (MSA_11080) phoU 1001835..1002488 (-) 654 WP_000946330.1 phosphate signaling complex protein PhoU -
  MSA_RS05400 (MSA_11090) pstB 1002522..1003280 (-) 759 WP_016480740.1 phosphate ABC transporter ATP-binding protein PstB -

Sequence

Protein


Download         Length: 437 a.a.        Molecular weight: 49678.12 Da        Isoelectric Point: 9.4961

>NTDB_id=59124 MSA_RS05380 WP_000042584.1 996995..998308(-) (ciaH) [Streptococcus agalactiae ILRI005]
MSKPIKISKFKKNVSDSHFIHFFTVFSGIFLVMTVIILQVMRYGVYSSVDSSLKYISTHPKNYINMVMSRTAAYLDNSNI
ASVKLKPGGQTVANTDILLFTSEEEVINYFDAFSNYQFLKPNKKNLGGISELTLTNIFGQDETYHAVTVKVNNPAYPNVT
YMTAIVNIDQLVNAKERYEKIIIFVMTTFWIISIGASIYLAKWAQKPIIENYERQKAFVENASHELRTPLAVLQNRLETL
FRKPNATILENSENIASSLDEVRNMRILTTNLLNLARRDDGIKPELAVIKPTLFDSIFENYDLIAQENGKNFTGHNMIQD
SFKTDKTLLKQLMTILFDNAIKYTDNDGSIDFTISETDKYLFLEIADNGPGISEEDKVRIFDRFYRVDKARTRQQGGFGL
GLSLAQQIVNSLRGNITVIDNKPRGSIFKIKLPKVKG

Nucleotide


Download         Length: 1314 bp        

>NTDB_id=59124 MSA_RS05380 WP_000042584.1 996995..998308(-) (ciaH) [Streptococcus agalactiae ILRI005]
ATGTCGAAACCGATTAAGATAAGTAAATTCAAAAAAAATGTCTCAGATAGTCATTTTATCCATTTTTTCACAGTTTTTAG
CGGTATTTTTCTGGTTATGACTGTTATCATCCTCCAAGTCATGCGCTATGGTGTTTATTCTTCTGTTGATAGTAGTTTAA
AGTATATCAGTACCCATCCTAAAAATTACATCAATATGGTTATGTCACGTACTGCTGCCTACCTAGATAACTCCAATATC
GCAAGTGTCAAGTTAAAACCCGGCGGTCAGACAGTAGCTAATACTGATATTCTTCTTTTTACATCAGAAGAAGAAGTCAT
TAACTATTTTGACGCATTTTCAAACTATCAGTTTTTAAAACCTAATAAAAAAAATCTAGGTGGCATTAGTGAATTAACTT
TAACCAATATTTTTGGTCAAGATGAGACATATCATGCTGTCACCGTAAAAGTTAATAACCCTGCTTATCCTAATGTGACT
TACATGACAGCTATTGTTAATATTGATCAATTAGTAAATGCTAAAGAACGCTATGAAAAAATTATTATATTTGTCATGAC
TACTTTTTGGATTATTTCAATTGGAGCAAGTATCTACTTAGCTAAATGGGCACAAAAACCGATTATAGAAAACTACGAAA
GACAGAAGGCTTTTGTCGAAAATGCTAGCCACGAGCTGCGTACTCCCCTAGCTGTCTTACAAAATCGCCTAGAAACGCTA
TTCAGAAAACCGAATGCCACCATTTTAGAAAATAGTGAAAATATCGCTTCAAGTCTAGATGAAGTACGAAATATGCGTAT
TTTAACCACTAATCTTTTAAACTTAGCAAGACGTGATGATGGAATCAAACCAGAATTAGCTGTTATTAAGCCTACACTTT
TTGATAGTATCTTTGAGAATTATGATCTAATCGCCCAAGAGAATGGTAAAAATTTTACTGGACATAATATGATTCAAGAT
AGTTTCAAAACAGATAAGACACTGCTAAAACAACTCATGACTATTTTATTTGATAATGCTATAAAATATACTGACAATGA
TGGTAGCATTGACTTTACCATATCTGAAACTGATAAGTATCTCTTTTTAGAAATCGCTGATAATGGACCAGGAATTTCAG
AGGAGGATAAAGTCAGAATTTTTGATCGTTTTTACCGTGTTGACAAAGCAAGAACACGACAACAAGGAGGATTTGGCCTC
GGTCTTTCTTTAGCTCAACAAATCGTTAACTCACTGCGAGGTAATATTACAGTAATTGATAATAAACCTAGAGGCAGTAT
TTTTAAGATAAAACTACCAAAAGTAAAAGGTTAG

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(325-434)

His Kinase A (phospho-acceptor) domain (HisKA)

(216-281)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

60.14

98.169

0.59
  ciaH Streptococcus pneumoniae Rx1

51.905

96.11

0.499
  ciaH Streptococcus pneumoniae D39

51.905

96.11

0.499
  ciaH Streptococcus pneumoniae R6

51.905

96.11

0.499
  ciaH Streptococcus pneumoniae TIGR4

51.905

96.11

0.499

Multiple sequence alignment