Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   LPB404_RS07670 Genome accession   NZ_CP079821
Coordinates   1516347..1517048 (-) Length   233 a.a.
NCBI ID   WP_125374347.1    Uniprot ID   -
Organism   Streptococcus rubneri strain LPB0404     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1511347..1522048
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LPB404_RS07650 (LPB404_07650) rnc 1512729..1513430 (-) 702 WP_125374528.1 ribonuclease III -
  LPB404_RS07655 (LPB404_07655) - 1513589..1513978 (-) 390 WP_373689705.1 YbaN family protein -
  LPB404_RS07660 (LPB404_07660) vicX 1514190..1514999 (-) 810 WP_023023917.1 MBL fold metallo-hydrolase Regulator
  LPB404_RS07665 (LPB404_07665) micB 1515008..1516354 (-) 1347 WP_125374346.1 cell wall metabolism sensor histidine kinase VicK Regulator
  LPB404_RS07670 (LPB404_07670) micA 1516347..1517048 (-) 702 WP_125374347.1 response regulator YycF Regulator
  LPB404_RS07675 (LPB404_07675) - 1517623..1518672 (+) 1050 WP_023023923.1 DUF389 domain-containing protein -
  LPB404_RS07680 (LPB404_07680) thrS 1519032..1520975 (-) 1944 WP_023023925.1 threonine--tRNA ligase -

Sequence

Protein


Download         Length: 233 a.a.        Molecular weight: 26629.57 Da        Isoelectric Point: 4.7260

>NTDB_id=589771 LPB404_RS07670 WP_125374347.1 1516347..1517048(-) (micA) [Streptococcus rubneri strain LPB0404]
MKKILVVDDEKPISDIIKFNMAKEGYEVLTAFDGKEALAIFEAESPDILILDLMLPEIDGLEVARTIRKTSNVPIIVLSA
KDTEFDKVIGLEIGADDYVTKPFSNRELQARVKALLRRTELTVESQTESTSDSDIVIGDLKIIPDAFLAQKKGKELELTH
REFELLYHLATHVGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDIPGRPEYILTRRGVGYYMRNND

Nucleotide


Download         Length: 702 bp        

>NTDB_id=589771 LPB404_RS07670 WP_125374347.1 1516347..1517048(-) (micA) [Streptococcus rubneri strain LPB0404]
ATGAAGAAAATTCTTGTTGTAGATGATGAAAAGCCGATTTCGGATATTATAAAATTCAATATGGCCAAAGAAGGCTATGA
AGTCTTGACTGCCTTCGATGGAAAAGAAGCACTGGCTATTTTTGAAGCTGAGAGCCCAGATATTTTGATCTTGGACCTCA
TGCTTCCTGAAATTGATGGTTTGGAAGTAGCACGTACCATTCGAAAGACCAGTAATGTGCCGATTATTGTCTTATCTGCA
AAAGATACAGAATTTGATAAGGTCATCGGTCTTGAAATTGGTGCGGATGACTATGTGACTAAGCCATTCTCAAATCGTGA
GCTTCAAGCTCGCGTAAAAGCTTTATTGCGTCGGACAGAACTAACGGTAGAATCACAGACAGAGTCTACATCAGATTCAG
ATATTGTGATTGGTGATTTGAAAATCATTCCGGATGCCTTCCTTGCTCAGAAAAAAGGCAAAGAGCTCGAGTTGACCCAT
CGCGAATTTGAGCTGCTCTATCACTTGGCAACCCATGTAGGCCAAGTCATGACCCGTGAGCATTTGCTGGAAACAGTCTG
GGGCTACGATTATTTTGGAGATGTTCGGACAGTGGACGTAACGATTCGACGTTTGCGTGAAAAAATCGAAGATATTCCAG
GCCGTCCGGAGTATATTTTAACGCGCCGCGGTGTCGGTTACTATATGAGAAACAATGATTAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(153-228)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

80.687

100

0.807
  vicR Streptococcus mutans UA159

77.542

100

0.785
  covR Lactococcus lactis subsp. lactis strain DGCC12653

45.022

99.142

0.446
  covR Streptococcus salivarius strain HSISS4

41.048

98.283

0.403