Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   LPB404_RS04610 Genome accession   NZ_CP079821
Coordinates   907308..907982 (+) Length   224 a.a.
NCBI ID   WP_117744091.1    Uniprot ID   -
Organism   Streptococcus rubneri strain LPB0404     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 902308..912982
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LPB404_RS04590 (LPB404_04590) phoU 902495..903148 (+) 654 WP_023022840.1 phosphate signaling complex protein PhoU -
  LPB404_RS04595 (LPB404_04595) - 903279..905822 (+) 2544 WP_219075150.1 M1 family metallopeptidase -
  LPB404_RS04600 (LPB404_04600) - 905878..906420 (-) 543 WP_219075151.1 biotin transporter BioY -
  LPB404_RS04605 (LPB404_04605) - 906628..907197 (+) 570 WP_219075152.1 hypothetical protein -
  LPB404_RS04610 (LPB404_04610) ciaR 907308..907982 (+) 675 WP_117744091.1 response regulator transcription factor Regulator
  LPB404_RS04615 (LPB404_04615) ciaH 907972..909345 (+) 1374 WP_219075153.1 cell wall metabolism sensor histidine kinase WalK Regulator
  LPB404_RS04620 (LPB404_04620) - 909596..909982 (+) 387 WP_023022851.1 VOC family protein -
  LPB404_RS04625 (LPB404_04625) - 910177..911562 (+) 1386 WP_048691392.1 polysaccharide deacetylase family protein -
  LPB404_RS04630 (LPB404_04630) - 911872..912960 (-) 1089 WP_219075154.1 DEAD/DEAH box helicase -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25235.99 Da        Isoelectric Point: 4.3669

>NTDB_id=589762 LPB404_RS04610 WP_117744091.1 907308..907982(+) (ciaR) [Streptococcus rubneri strain LPB0404]
MIKILLVEDDLGLSNSVFDFLDDFADVMQVFDGDEGLYEAESGIYDLILLDLMLPGKDGFQVLKELRDKGVSTPVLIMTA
KESLDDKGHGFELGADDYLTKPFYLEELKMRIQALLKRAGKVNENTLSYGNVTVNLSTNSTLVEGKEVELLGKEFDLLVY
FLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKIRKKLKGTDFAKNLQTLRSVGYILKDAQ

Nucleotide


Download         Length: 675 bp        

>NTDB_id=589762 LPB404_RS04610 WP_117744091.1 907308..907982(+) (ciaR) [Streptococcus rubneri strain LPB0404]
ATGATTAAGATTTTATTAGTCGAAGATGACCTTGGTTTGTCTAATTCAGTATTTGATTTTTTAGATGATTTTGCAGATGT
CATGCAAGTCTTTGATGGGGATGAAGGTTTGTATGAGGCTGAAAGTGGCATCTATGACCTAATTTTACTGGACCTCATGC
TTCCTGGCAAAGATGGTTTCCAAGTTCTGAAAGAATTGAGAGATAAGGGGGTCTCCACTCCGGTATTGATTATGACAGCC
AAAGAGAGCTTGGACGATAAGGGCCATGGTTTTGAGTTGGGAGCAGATGACTATCTGACCAAGCCTTTCTACCTAGAAGA
GTTGAAAATGCGAATCCAAGCATTGTTGAAGCGCGCTGGTAAGGTCAATGAAAATACTCTTTCTTATGGGAATGTGACCG
TTAATCTCTCGACTAACTCTACGCTTGTTGAAGGGAAAGAAGTAGAACTATTAGGAAAAGAATTTGATCTTTTGGTCTAT
TTCCTTCAAAATCAAAATGTCATCCTGCCAAAAACACAAATCTTTGATCGACTTTGGGGATTTGATAGCGATACGACCAT
TTCGGTTGTCGAAGTGTATGTTTCTAAGATTCGTAAGAAATTAAAAGGTACAGACTTTGCAAAAAATCTCCAAACATTGC
GTAGCGTGGGGTATATTCTAAAAGATGCTCAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

89.732

100

0.897
  ciaR Streptococcus pneumoniae D39

89.732

100

0.897
  ciaR Streptococcus pneumoniae R6

89.732

100

0.897
  ciaR Streptococcus pneumoniae TIGR4

89.732

100

0.897
  ciaR Streptococcus mutans UA159

87.054

100

0.871
  covR Lactococcus lactis subsp. lactis strain DGCC12653

38.428

100

0.393
  vicR Streptococcus mutans UA159

34.764

100

0.362