Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   LPB404_RS04615 Genome accession   NZ_CP079821
Coordinates   907972..909345 (+) Length   457 a.a.
NCBI ID   WP_219075153.1    Uniprot ID   -
Organism   Streptococcus rubneri strain LPB0404     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 902972..914345
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LPB404_RS04595 (LPB404_04595) - 903279..905822 (+) 2544 WP_219075150.1 M1 family metallopeptidase -
  LPB404_RS04600 (LPB404_04600) - 905878..906420 (-) 543 WP_219075151.1 biotin transporter BioY -
  LPB404_RS04605 (LPB404_04605) - 906628..907197 (+) 570 WP_219075152.1 hypothetical protein -
  LPB404_RS04610 (LPB404_04610) ciaR 907308..907982 (+) 675 WP_117744091.1 response regulator transcription factor Regulator
  LPB404_RS04615 (LPB404_04615) ciaH 907972..909345 (+) 1374 WP_219075153.1 cell wall metabolism sensor histidine kinase WalK Regulator
  LPB404_RS04620 (LPB404_04620) - 909596..909982 (+) 387 WP_023022851.1 VOC family protein -
  LPB404_RS04625 (LPB404_04625) - 910177..911562 (+) 1386 WP_048691392.1 polysaccharide deacetylase family protein -
  LPB404_RS04630 (LPB404_04630) - 911872..912960 (-) 1089 WP_219075154.1 DEAD/DEAH box helicase -
  LPB404_RS04635 (LPB404_04635) - 912962..913939 (-) 978 WP_219075155.1 Gfo/Idh/MocA family protein -

Sequence

Protein


Download         Length: 457 a.a.        Molecular weight: 52353.71 Da        Isoelectric Point: 6.7599

>NTDB_id=589763 LPB404_RS04615 WP_219075153.1 907972..909345(+) (ciaH) [Streptococcus rubneri strain LPB0404]
MLNKIKKTVNADDFSYFIRYFGLFTLIFSTMTLIIIQVMRSSLYTTVDENLKMLSKDRYSIISLANRTGNGMGRDETADD
GPEDDELGPEDGPRPSVTSNSTAILLNDKFENVTTDNGFLDLKTVTFSRSYLNKIKQIQITNHYKQKESYRAYLVDIDPD
DYIDGVKYAVIMTNISQLEQTSEKHESQIALVMICFWGISLFASIFLAKMSVKPLLESMNRQKAFVENASHELRTPLAVL
QNRLETLFRKPEATIMESSENIASSLDEVRNMRLLTTNLLNLARRDDGIKPEFSEIAPSFFDQTFANYEIIAEENEKIFE
YENLVDRSLVTDKVLLKQLMTILYDNALKYTEEEGKIRFIAQFKDRYLYLRVEDNGPGIADEDKKRIFDRFYRVDKARTR
QKGGFGLGLSLAKQIVEAFNGTISVRDNKPKGSIFEVKLATKSESKKRSSSKSTKNK

Nucleotide


Download         Length: 1374 bp        

>NTDB_id=589763 LPB404_RS04615 WP_219075153.1 907972..909345(+) (ciaH) [Streptococcus rubneri strain LPB0404]
ATGCTCAATAAAATTAAAAAAACTGTCAATGCGGATGACTTTTCTTATTTCATCCGCTATTTCGGACTCTTTACCTTGAT
TTTCTCAACCATGACCTTGATTATTATTCAGGTGATGCGTTCCAGTCTTTATACAACGGTTGACGAAAATTTAAAAATGC
TCAGTAAAGATCGCTATTCGATTATCAGTTTGGCAAACCGTACAGGCAATGGGATGGGAAGAGACGAAACTGCTGATGAC
GGCCCAGAAGATGATGAACTTGGTCCCGAGGATGGCCCTAGACCATCGGTTACTTCTAATAGCACAGCTATCCTCTTGAA
TGATAAATTTGAAAATGTGACGACGGATAATGGTTTCCTAGATCTAAAAACAGTCACTTTTAGTCGCAGTTATTTAAACA
AGATCAAGCAGATTCAAATTACTAATCATTATAAGCAGAAGGAAAGTTACCGAGCTTATTTGGTAGATATTGATCCCGAT
GATTATATCGACGGGGTGAAATATGCCGTGATCATGACCAACATCAGCCAGTTGGAGCAGACCAGTGAAAAACATGAGAG
TCAAATTGCCTTGGTCATGATTTGTTTCTGGGGCATTTCCCTCTTTGCAAGTATCTTCCTGGCTAAGATGAGTGTGAAAC
CTCTCTTAGAGAGCATGAACCGGCAGAAGGCCTTCGTCGAAAATGCCTCTCATGAATTGCGGACGCCTTTAGCGGTTTTG
CAAAATCGTTTGGAAACCTTATTCCGCAAACCAGAGGCAACGATTATGGAATCTAGTGAGAATATCGCCTCCTCTTTGGA
TGAAGTTCGCAATATGCGCTTATTGACGACCAATCTCTTAAACTTAGCCCGTCGAGATGATGGGATTAAACCAGAGTTTA
GCGAGATCGCACCATCCTTTTTTGACCAAACTTTTGCCAATTATGAAATCATTGCGGAGGAAAACGAAAAAATCTTCGAA
TATGAGAATCTGGTGGATAGGAGTCTGGTGACTGATAAGGTCCTATTGAAACAACTGATGACCATTTTGTATGATAATGC
CCTCAAATATACAGAGGAAGAAGGAAAAATACGCTTTATCGCCCAATTCAAGGATCGTTATCTCTATCTTCGAGTAGAGG
ACAATGGTCCAGGAATTGCTGATGAAGATAAAAAACGGATTTTTGATCGTTTCTATCGAGTGGATAAGGCGCGAACCCGT
CAAAAGGGTGGTTTTGGTTTAGGCTTATCCTTAGCCAAGCAAATTGTAGAAGCCTTCAATGGTACCATTAGTGTTCGAGA
TAACAAACCTAAAGGTTCTATTTTCGAAGTGAAACTAGCAACTAAGTCAGAAAGTAAAAAGAGATCCAGTTCTAAATCAA
CGAAGAACAAGTAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(223-288)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(332-439)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus pneumoniae Rx1

60.356

98.249

0.593
  ciaH Streptococcus pneumoniae D39

60.356

98.249

0.593
  ciaH Streptococcus pneumoniae R6

60.356

98.249

0.593
  ciaH Streptococcus pneumoniae TIGR4

60.356

98.249

0.593
  ciaH Streptococcus mutans UA159

51.025

96.061

0.49