Detailed information NTG0589732

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: LPB404_RS01925
• Genome accession: NZ_CP079821
• Coordinates: 375440..375892 (+)
• Length: 150 a.a.
• NCBI ID: WP_219075203.1
• Uniprot ID: -
• Organism: Streptococcus rubneri strain LPB0404
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 370440..380892

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LPB404_RS01895 (LPB404_01895)	-	372102..372479 (+)	378	WP_219074901.1	DUF1033 family protein	-
LPB404_RS01900 (LPB404_01900)	comYA	372584..373543 (+)	960	WP_219074902.1	competence type IV pilus ATPase ComGA	Machinery gene
LPB404_RS01905 (LPB404_01905)	comYB	373467..374489 (+)	1023	WP_257573088.1	competence type IV pilus assembly protein ComGB	Machinery gene
LPB404_RS01910 (LPB404_01910)	comGC/cglC	374486..374803 (+)	318	WP_219074903.1	competence type IV pilus major pilin ComGC	Machinery gene
LPB404_RS01915 (LPB404_01915)	comGD/cglD	374793..375197 (+)	405	WP_219075204.1	competence type IV pilus minor pilin ComGD	Machinery gene
LPB404_RS01920 (LPB404_01920)	comGE	375163..375456 (+)	294	WP_219074904.1	competence type IV pilus minor pilin ComGE	-
LPB404_RS01925 (LPB404_01925)	comGF/cglF	375440..375892 (+)	453	WP_219075203.1	competence type IV pilus minor pilin ComGF	Machinery gene
LPB404_RS01930 (LPB404_01930)	comGG	375921..376304 (+)	384	WP_374030902.1	competence type IV pilus minor pilin ComGG	-
LPB404_RS01935 (LPB404_01935)	comYH	376336..377289 (+)	954	WP_120701351.1	class I SAM-dependent methyltransferase	Machinery gene
LPB404_RS01940 (LPB404_01940)	-	377338..378534 (+)	1197	WP_219074906.1	acetate kinase	-
LPB404_RS01945 (LPB404_01945)	-	378687..379361 (+)	675	WP_244917016.1	CPBP family intramembrane glutamic endopeptidase	-
LPB404_RS01950 (LPB404_01950)	folP	379520..380476 (+)	957	WP_257573047.1	dihydropteroate synthase	-

Sequence

Protein

• Length: 150 a.a.
• Molecular weight: 16990.63 Da
• Isoelectric Point: 5.0425

>NTDB_id=589732 LPB404_RS01925 WP_219075203.1 375440..375892(+) (comGF/cglF) [Streptococcus rubneri strain LPB0404]
MLKRNKLPAFTLLEALVALLVISGGLLVFQGLTSLLRQELQYQSQIKQEEWLLFQDQLDIELSRSQFEGVRDNKLYLVQD
QKPIAIGLAKGGDIRKTDATGRGYQPMIDGVESALIEKRGDLVSIQLRFAEGLEREVVYRVVDKDKKEAD

Nucleotide

• Length: 453 bp

>NTDB_id=589732 LPB404_RS01925 WP_219075203.1 375440..375892(+) (comGF/cglF) [Streptococcus rubneri strain LPB0404]
CTGTTGAAAAGAAATAAACTTCCAGCCTTTACTTTACTGGAGGCTTTGGTTGCCTTGCTCGTTATCAGTGGTGGTTTATT
GGTGTTTCAAGGATTGACAAGCCTCTTGCGTCAAGAACTCCAGTACCAAAGCCAAATCAAGCAAGAAGAGTGGTTGCTTT
TTCAGGACCAACTGGACATTGAATTATCTCGGAGCCAATTTGAAGGGGTCAGAGACAATAAACTCTATCTTGTTCAGGAT
CAGAAACCCATAGCCATTGGATTGGCTAAAGGGGGAGATATCCGAAAGACAGATGCGACTGGCCGTGGCTACCAACCGAT
GATAGACGGAGTCGAATCCGCCTTGATTGAAAAAAGAGGGGATTTAGTATCTATTCAACTTCGCTTTGCAGAAGGATTAG
AAAGGGAGGTGGTCTACCGTGTGGTGGATAAGGATAAAAAAGAAGCAGATTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (37-134)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus pneumoniae Rx1	57.554	92.667	0.533
comGF/cglF	Streptococcus pneumoniae D39	57.554	92.667	0.533
comGF/cglF	Streptococcus pneumoniae R6	57.554	92.667	0.533
comGF/cglF	Streptococcus pneumoniae TIGR4	57.554	92.667	0.533
comGF/cglF	Streptococcus mitis NCTC 12261	56.115	92.667	0.52
comGF/cglF	Streptococcus mitis SK321	56.115	92.667	0.52
comYF	Streptococcus mutans UA159	41.379	96.667	0.4
comYF	Streptococcus mutans UA140	41.379	96.667	0.4
comGF	Lactococcus lactis subsp. cremoris KW2	40.58	92	0.373