Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Regulator
Locus tag   KX728_RS00210 Genome accession   NZ_CP079724
Coordinates   35380..36729 (+) Length   449 a.a.
NCBI ID   WP_215805103.1    Uniprot ID   -
Organism   Streptococcus oralis strain 34     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 30380..41729
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KX728_RS00170 (KX728_00170) - 30940..31176 (+) 237 WP_045593788.1 acyl carrier protein -
  KX728_RS00175 (KX728_00175) - 31495..31638 (+) 144 WP_000180838.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  KX728_RS00180 (KX728_00180) - 31656..31805 (+) 150 WP_001052546.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  KX728_RS00185 (KX728_00185) - 31818..31994 (+) 177 WP_000793177.1 hypothetical protein -
  KX728_RS00190 (KX728_00190) - 32144..32299 (+) 156 WP_000661692.1 hypothetical protein -
  KX728_RS00195 (KX728_00195) - 32324..32545 (+) 222 WP_001081404.1 hypothetical protein -
  KX728_RS00200 (KX728_00200) - 32583..32771 (+) 189 WP_000722236.1 hypothetical protein -
  KX728_RS00205 (KX728_00205) comA 33214..35367 (+) 2154 WP_215805102.1 peptide cleavage/export ABC transporter Regulator
  KX728_RS00210 (KX728_00210) comB 35380..36729 (+) 1350 WP_215805103.1 HlyD family secretion protein Regulator
  KX728_RS00215 (KX728_00215) purC 36898..37605 (+) 708 WP_215805104.1 phosphoribosylaminoimidazolesuccinocarboxamide synthase -
  KX728_RS00220 (KX728_00220) - 37662..41386 (+) 3725 Protein_37 phosphoribosylformylglycinamidine synthase -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 49891.70 Da        Isoelectric Point: 4.9665

>NTDB_id=588946 KX728_RS00210 WP_215805103.1 35380..36729(+) (comB) [Streptococcus oralis strain 34]
MKPEFLESAEFYNRRYHNFSSRVILPMSLLFVFLLGFAVFAEKEISLSTRATVEPSRIIANIQSTSNQRIVANYLEENKL
VKQGDLLVEYQQGAEAVQAEAYASQLEMLKDQKKQLGYLQSSLKEGSDQFPEADKFGYQEMFRDYLSQASSLRSNVSQQN
ASISSQNAAASQSQAEIGNLISQTEDKIRDYKTAKSAIEKGDQLDSQNAAYSFYQTYKNQAGDDSQAKSQVIAQVDAQIA
QLESSLATYRVQYAGSGAQQAYATGLDSQLESLKSQHLVKVGQELTLLDQKILEAESGKKVQGGLLDKGKIIASEDGVLH
LNPETSESTMVAEGTLLAQLYPSLEKEGKTKLTAYLSSKDVARVKIGDSVRYTTTNDAKNQIFLDSTITSIDATATKTEK
GNFFKIEAETSLTPEQAESLRYGSEGRLTLITGKKSYLRYYWDQFLNRE

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=588946 KX728_RS00210 WP_215805103.1 35380..36729(+) (comB) [Streptococcus oralis strain 34]
ATGAAACCAGAATTTTTAGAAAGTGCGGAGTTTTATAATCGTCGTTACCATAATTTTTCCAGTCGGGTGATTTTACCTAT
GTCACTTCTGTTCGTGTTTTTACTAGGATTTGCAGTTTTTGCAGAGAAAGAGATTAGTTTGTCTACTAGAGCTACTGTCG
AACCTAGTCGGATCATTGCCAACATCCAGTCGACTAGCAATCAACGGATTGTGGCAAATTATCTGGAAGAAAATAAACTG
GTCAAGCAGGGGGATTTACTCGTTGAGTACCAGCAGGGGGCGGAAGCTGTTCAAGCTGAAGCATACGCCAGTCAATTGGA
GATGTTAAAGGATCAAAAAAAGCAGTTGGGGTATTTGCAATCCAGTTTGAAAGAGGGGAGTGATCAATTTCCAGAGGCGG
ATAAGTTTGGATATCAGGAGATGTTTCGAGACTATCTCAGCCAAGCTAGTAGTCTTAGGAGCAATGTTTCTCAACAAAAT
GCCAGCATCTCTTCTCAAAATGCAGCCGCAAGTCAGAGTCAGGCTGAGATTGGCAACCTTATCAGCCAAACAGAGGATAA
AATCCGAGATTACAAAACAGCTAAGTCGGCGATTGAAAAAGGAGATCAACTGGATAGTCAAAATGCAGCCTACTCATTTT
ATCAGACTTATAAAAACCAAGCTGGAGATGATTCGCAAGCTAAATCGCAAGTTATTGCACAGGTGGATGCACAAATTGCC
CAGCTAGAGTCTAGTTTAGCTACTTATCGTGTGCAGTATGCGGGTTCTGGAGCTCAACAAGCCTACGCAACGGGACTGGA
TAGTCAACTGGAATCCCTCAAGTCTCAGCACCTAGTCAAAGTCGGCCAGGAATTAACCCTTTTGGATCAGAAAATTTTGG
AGGCAGAGTCGGGTAAGAAAGTCCAAGGAGGTCTGCTGGACAAGGGGAAAATTATAGCAAGTGAGGATGGGGTGCTTCAC
CTTAATCCTGAGACCAGTGAATCTACGATGGTTGCAGAAGGAACTCTGCTAGCCCAGCTCTATCCATCCTTGGAAAAAGA
AGGCAAAACCAAACTCACAGCCTATCTCAGTTCAAAAGATGTTGCTAGAGTTAAGATTGGGGACTCTGTCCGTTATACTA
CGACTAATGATGCGAAGAATCAAATCTTCCTGGATTCTACGATTACAAGTATTGATGCGACAGCTACCAAGACTGAAAAG
GGCAATTTCTTTAAAATAGAGGCGGAGACCAGTCTGACTCCTGAACAGGCAGAAAGTCTTCGCTATGGTTCAGAAGGGCG
TTTGACGCTAATCACAGGGAAGAAAAGCTATTTGCGCTATTATTGGGATCAATTTTTGAACAGAGAATAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Streptococcus mitis SK321

82.405

100

0.824
  comB Streptococcus pneumoniae Rx1

81.514

100

0.815
  comB Streptococcus pneumoniae D39

81.514

100

0.815
  comB Streptococcus pneumoniae R6

81.514

100

0.815
  comB Streptococcus pneumoniae TIGR4

81.069

100

0.811
  comB Streptococcus mitis NCTC 12261

80.401

100

0.804
  comB Streptococcus gordonii str. Challis substr. CH1

54.667

100

0.548