Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   KX728_RS00205 Genome accession   NZ_CP079724
Coordinates   33214..35367 (+) Length   717 a.a.
NCBI ID   WP_215805102.1    Uniprot ID   -
Organism   Streptococcus oralis strain 34     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 28214..40367
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KX728_RS00160 (KX728_00160) recO 29175..29945 (+) 771 WP_070534765.1 DNA repair protein RecO -
  KX728_RS00165 (KX728_00165) plsX 29942..30934 (+) 993 WP_084917282.1 phosphate acyltransferase PlsX -
  KX728_RS00170 (KX728_00170) - 30940..31176 (+) 237 WP_045593788.1 acyl carrier protein -
  KX728_RS00175 (KX728_00175) - 31495..31638 (+) 144 WP_000180838.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  KX728_RS00180 (KX728_00180) - 31656..31805 (+) 150 WP_001052546.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  KX728_RS00185 (KX728_00185) - 31818..31994 (+) 177 WP_000793177.1 hypothetical protein -
  KX728_RS00190 (KX728_00190) - 32144..32299 (+) 156 WP_000661692.1 hypothetical protein -
  KX728_RS00195 (KX728_00195) - 32324..32545 (+) 222 WP_001081404.1 hypothetical protein -
  KX728_RS00200 (KX728_00200) - 32583..32771 (+) 189 WP_000722236.1 hypothetical protein -
  KX728_RS00205 (KX728_00205) comA 33214..35367 (+) 2154 WP_215805102.1 peptide cleavage/export ABC transporter Regulator
  KX728_RS00210 (KX728_00210) comB 35380..36729 (+) 1350 WP_215805103.1 HlyD family secretion protein Regulator
  KX728_RS00215 (KX728_00215) purC 36898..37605 (+) 708 WP_215805104.1 phosphoribosylaminoimidazolesuccinocarboxamide synthase -

Sequence

Protein


Download         Length: 717 a.a.        Molecular weight: 80276.49 Da        Isoelectric Point: 7.0553

>NTDB_id=588945 KX728_RS00205 WP_215805102.1 33214..35367(+) (comA) [Streptococcus oralis strain 34]
MKFRKRHYRPQVDQMDCGVASLAMVFGYYGSYYSLAHLRELAKTTMDGTTALGLVKVAEEIGFETRAIKADMTLFDLPDL
TFPFAAHVLKEGKLLHYYVVIGQDKKYIHIADPDPGVKLTKISRERFAQEWTGVSIFMAPSPSYKPHKEKKQGLLSFMPI
LLKQHGLITNIVLATLLVTLINIVGSYYLQSIIDSYVPDQMRSTLGIISIGLVIVYILQQILSHAQEYLLLVLGQRLSID
VILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSIIDALASTILSIFLDVSTILIISLVLFSQNITLFFISLLALPIYTV
IIFAFMKPFEKMNRDTMEANAVLSSSIIEDINGIETIKSLTSESSRYQKIDKEFVAYLKKSFTYSRAESQQKALKKVAQL
LLNVAVLWLGAILVMDGKMSLGQLITHNTLLVYFTNPLENIINLQTKLQTAQVANNRLNEVYLVASEFEEKKTVEDLSMM
NGDMTFKQVHYKYGYGRDVLSDINLTIPQGSKVAFVGISGSGKTTLAKMMVNFYDPSQGEISLGGVNLNQIDKKALRQYI
NYLPQQPYVFNGTILENLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISGGQRQRIALARALLTDA
PVLILDEATSSLDILTEKRIVDNLMALDKTLIFIAHRLTIAERTEKVVVLEQGKIVEEGTHAGLLAQDGFYAHLVNS

Nucleotide


Download         Length: 2154 bp        

>NTDB_id=588945 KX728_RS00205 WP_215805102.1 33214..35367(+) (comA) [Streptococcus oralis strain 34]
ATGAAATTTAGGAAAAGGCACTATCGTCCCCAGGTGGATCAGATGGATTGTGGCGTGGCTTCCTTAGCCATGGTATTTGG
CTACTATGGTAGTTATTACTCCTTGGCTCATCTACGAGAATTAGCCAAGACGACCATGGATGGGACAACGGCTTTGGGTT
TGGTCAAGGTGGCAGAGGAGATTGGGTTTGAGACGCGGGCTATCAAGGCGGATATGACGCTTTTTGATCTGCCAGATTTG
ACCTTTCCTTTTGCGGCTCATGTGCTCAAGGAAGGGAAATTGCTCCACTACTATGTGGTGATAGGTCAGGATAAAAAGTA
CATTCATATCGCTGATCCGGATCCGGGTGTCAAGCTGACTAAGATTTCCCGTGAGCGATTTGCGCAAGAATGGACAGGGG
TTAGTATTTTTATGGCGCCATCTCCGAGCTATAAACCTCATAAGGAGAAAAAACAGGGGCTCTTATCCTTCATGCCGATT
TTACTCAAACAGCATGGCTTAATTACCAATATCGTCCTAGCGACACTCTTGGTAACACTGATTAACATTGTAGGTTCTTA
TTATCTACAGTCTATCATTGATAGTTACGTACCAGATCAGATGCGTTCGACCTTGGGCATTATCTCAATAGGACTAGTCA
TCGTCTATATCCTCCAGCAGATTTTGTCCCATGCGCAGGAATACCTTTTACTTGTTCTGGGGCAACGCTTGTCCATCGAT
GTGATTTTGTCCTACATCAAGCATGTTTTTCACCTGCCGATGTCCTTTTTTGCGACACGCAGAACAGGGGAAATCGTTTC
TCGTTTTACAGATGCTAACAGTATCATCGACGCGCTAGCTTCGACCATTCTTTCGATTTTCCTAGATGTGTCGACGATTT
TGATTATCTCGCTTGTGCTATTTTCACAGAACATCACGCTCTTTTTCATTAGTCTGCTTGCACTTCCTATCTATACCGTG
ATTATCTTTGCTTTTATGAAGCCGTTTGAAAAGATGAATCGGGATACCATGGAAGCCAATGCGGTTCTGTCTTCTTCTAT
CATTGAGGACATCAACGGTATTGAGACTATTAAATCTTTGACCAGTGAGAGTTCGCGCTATCAAAAGATTGATAAGGAAT
TTGTGGCTTATCTAAAAAAATCTTTTACCTATAGTCGGGCAGAAAGCCAGCAAAAGGCTCTGAAAAAAGTTGCCCAGCTC
CTGCTCAATGTTGCCGTTCTCTGGCTAGGAGCTATTCTTGTCATGGATGGGAAAATGAGTTTGGGCCAGCTGATTACCCA
TAATACTTTGCTTGTTTACTTTACCAATCCTTTGGAAAATATCATTAACCTACAAACCAAACTTCAGACAGCGCAGGTTG
CCAATAATCGCTTAAATGAGGTTTATCTAGTAGCTTCGGAGTTTGAGGAGAAGAAAACGGTAGAAGATTTGAGCATGATG
AATGGAGATATGACCTTTAAGCAGGTTCACTATAAGTATGGCTATGGTCGAGATGTCTTGTCGGATATCAATTTGACCAT
TCCGCAAGGGTCTAAGGTAGCTTTTGTGGGGATTTCAGGTTCGGGTAAGACCACCTTAGCCAAGATGATGGTTAATTTTT
ACGACCCAAGTCAGGGAGAGATTAGTCTGGGTGGTGTCAATCTCAATCAGATTGATAAAAAGGCCCTGCGCCAGTACATC
AACTATTTGCCTCAACAGCCCTATGTTTTTAACGGAACGATTTTGGAGAATCTTCTCCTTGGAGCCAAGGAGGGGACGAC
TCAGGAAGACATCTTACGGGCGGTTGAGTTGGCCGAGATTCGGGAGGATATTGAGCGTATGCCCCTGAATTACCAGACAG
AATTAACTTCGGATGGGGCTGGAATTTCTGGTGGGCAACGGCAGAGAATCGCTCTGGCGCGTGCTCTCTTGACAGATGCG
CCTGTCTTGATTTTGGACGAGGCGACTAGCAGTTTGGATATTTTGACAGAAAAGCGAATCGTGGATAATCTTATGGCTTT
GGATAAGACCTTGATTTTCATCGCCCATCGCTTGACCATCGCTGAGCGGACAGAAAAGGTTGTTGTTTTGGAGCAGGGCA
AGATTGTCGAAGAGGGCACCCATGCAGGCTTGCTTGCACAGGATGGCTTTTATGCCCATTTGGTCAATAGCTAG

Domains

Predicted by InterproScan.

ABC transporter transmembrane region (ABC_membrane)

(170-438)

ABC transporter (ABC_tran)

(500-650)

Peptidase C39 family (Peptidase_C39)

(7-142)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus mitis NCTC 12261

94.142

100

0.941
  comA Streptococcus pneumoniae D39

93.863

100

0.939
  comA Streptococcus pneumoniae R6

93.863

100

0.939
  comA Streptococcus pneumoniae Rx1

93.863

100

0.939
  comA Streptococcus mitis SK321

93.724

100

0.937
  comA Streptococcus pneumoniae TIGR4

93.445

100

0.934
  comA Streptococcus gordonii str. Challis substr. CH1

80.474

100

0.805
  comA/nlmT Streptococcus mutans UA159

64.854

100

0.649