Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   KWY62_RS00715 Genome accession   NZ_CP079193
Coordinates   117048..118085 (+) Length   345 a.a.
NCBI ID   WP_238492613.1    Uniprot ID   -
Organism   Streptococcus suis strain ID41570     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 112048..123085
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KWY62_RS00700 (KWY62_00700) - 114750..115115 (+) 366 WP_024395451.1 DUF1033 family protein -
  KWY62_RS00705 (KWY62_00705) - 115150..116100 (-) 951 WP_014637311.1 S66 peptidase family protein -
  KWY62_RS00710 (KWY62_00710) comYA 116186..117136 (+) 951 WP_105140681.1 competence type IV pilus ATPase ComGA Machinery gene
  KWY62_RS00715 (KWY62_00715) comYB 117048..118085 (+) 1038 WP_238492613.1 competence type IV pilus assembly protein ComGB Machinery gene
  KWY62_RS00720 (KWY62_00720) comYC 118087..118368 (+) 282 WP_024395447.1 competence type IV pilus major pilin ComGC Machinery gene
  KWY62_RS00725 (KWY62_00725) comGD 118349..118756 (+) 408 WP_024395446.1 competence type IV pilus minor pilin ComGD -
  KWY62_RS00730 (KWY62_00730) comYE 118728..119021 (+) 294 WP_002936548.1 competence type IV pilus minor pilin ComGE Machinery gene
  KWY62_RS00735 (KWY62_00735) comGF/cglF 119008..119442 (+) 435 WP_024395445.1 competence type IV pilus minor pilin ComGF Machinery gene
  KWY62_RS00740 (KWY62_00740) comGG 119420..119830 (+) 411 WP_024395444.1 competence type IV pilus minor pilin ComGG -
  KWY62_RS00745 (KWY62_00745) comYH 119887..120840 (+) 954 WP_044776365.1 class I SAM-dependent methyltransferase Machinery gene
  KWY62_RS00750 (KWY62_00750) - 120890..122077 (+) 1188 WP_014637319.1 acetate kinase -
  KWY62_RS00755 (KWY62_00755) - 122338..122889 (+) 552 WP_014637320.1 folate family ECF transporter S component -

Sequence

Protein


Download         Length: 345 a.a.        Molecular weight: 38924.91 Da        Isoelectric Point: 9.0934

>NTDB_id=588137 KWY62_RS00715 WP_238492613.1 117048..118085(+) (comYB) [Streptococcus suis strain ID41570]
MNKLIAFLQQDISVFGRQKQKKLPLARQRKVIELFNNLFASGFHLGEIVDFLKRSQLLADPYTQVLSDGLLAGKPFSSLL
ADLRFSDAVVTQVALAEVHGNTSLSLSHIQSYLENVSKVRKKLIEVATYPIILLVFLLLIMLGLKNYLLPQLEEGNAATV
LINHLPTIFLSLSGLSLVAVLAGMVWFRKTNKIKVFSCLAALPFFGKLIQIYLTAYYAREWGSLIGQGLDLPQIVGLMQE
QQSQLFREIGQDLEQSLSNGQSFHEHIKTYAFFKRELSLIVEYGQVKSKLGGELTVYAAECWEDFFSRVNRAMQLIQPLV
FLFVALMVVLIYAAMLLPIYQNMEL

Nucleotide


Download         Length: 1038 bp        

>NTDB_id=588137 KWY62_RS00715 WP_238492613.1 117048..118085(+) (comYB) [Streptococcus suis strain ID41570]
ATGAACAAATTGATCGCCTTTTTGCAGCAGGACATATCAGTCTTCGGCAGGCAGAAACAGAAAAAATTACCCTTGGCTCG
CCAGCGTAAGGTCATTGAGCTTTTCAATAATCTTTTTGCCAGCGGTTTTCATCTGGGGGAGATTGTTGATTTCCTCAAAC
GTAGCCAGCTTCTGGCAGATCCCTATACCCAGGTCTTGTCAGACGGGCTGTTAGCAGGCAAACCCTTTTCAAGTTTGCTG
GCAGATTTGCGGTTTTCGGATGCGGTGGTCACACAGGTGGCTCTGGCAGAAGTTCATGGTAATACCAGCCTGAGTTTGAG
CCATATCCAGTCCTATCTGGAAAATGTCAGCAAGGTTCGTAAAAAATTGATTGAGGTGGCGACCTATCCGATTATCTTAC
TGGTTTTTTTGCTCTTGATTATGCTGGGTTTGAAAAACTATCTTCTGCCCCAGTTGGAGGAAGGCAATGCAGCGACCGTG
CTGATTAATCATCTACCGACCATCTTTTTATCTCTAAGTGGACTTAGTTTGGTGGCGGTCTTAGCTGGTATGGTTTGGTT
TCGCAAAACCAATAAAATTAAGGTCTTTTCCTGCTTGGCAGCTCTGCCATTTTTCGGAAAACTCATCCAAATCTATCTGA
CGGCCTATTACGCCAGGGAGTGGGGGAGTTTGATTGGGCAAGGCTTGGACCTGCCGCAGATTGTGGGCTTGATGCAAGAG
CAGCAGTCGCAGCTTTTTCGGGAGATTGGCCAGGACCTGGAGCAGTCGCTTTCCAATGGTCAGAGCTTTCACGAACACAT
TAAGACCTACGCCTTTTTTAAGCGGGAGCTGAGTTTGATTGTCGAGTATGGTCAGGTCAAGTCCAAGTTGGGTGGCGAGT
TGACAGTTTATGCAGCCGAGTGTTGGGAGGATTTTTTCTCTCGGGTCAATAGAGCCATGCAGCTAATCCAACCGCTGGTC
TTTCTCTTTGTGGCCTTAATGGTCGTTCTCATCTACGCAGCCATGTTGCTGCCGATTTATCAAAATATGGAGTTATAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(33-150)

Type II secretion system (T2SS), protein F (T2SSF)

(218-338)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus gordonii str. Challis substr. CH1

63.45

99.13

0.629
  comYB Streptococcus mutans UA140

59.184

99.42

0.588
  comYB Streptococcus mutans UA159

59.184

99.42

0.588
  comGB/cglB Streptococcus mitis NCTC 12261

60

97.101

0.583
  comGB/cglB Streptococcus mitis SK321

59.701

97.101

0.58
  comGB/cglB Streptococcus pneumoniae Rx1

59.403

97.101

0.577
  comGB/cglB Streptococcus pneumoniae D39

59.403

97.101

0.577
  comGB/cglB Streptococcus pneumoniae R6

59.403

97.101

0.577
  comGB/cglB Streptococcus pneumoniae TIGR4

59.403

97.101

0.577
  comGB Lactococcus lactis subsp. cremoris KW2

50.742

97.681

0.496