Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYE   Type   Machinery gene
Locus tag   KWY62_RS00730 Genome accession   NZ_CP079193
Coordinates   118728..119021 (+) Length   97 a.a.
NCBI ID   WP_002936548.1    Uniprot ID   A0AAJ2PIZ8
Organism   Streptococcus suis strain ID41570     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 113728..124021
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KWY62_RS00700 (KWY62_00700) - 114750..115115 (+) 366 WP_024395451.1 DUF1033 family protein -
  KWY62_RS00705 (KWY62_00705) - 115150..116100 (-) 951 WP_014637311.1 S66 peptidase family protein -
  KWY62_RS00710 (KWY62_00710) comYA 116186..117136 (+) 951 WP_105140681.1 competence type IV pilus ATPase ComGA Machinery gene
  KWY62_RS00715 (KWY62_00715) comYB 117048..118085 (+) 1038 WP_238492613.1 competence type IV pilus assembly protein ComGB Machinery gene
  KWY62_RS00720 (KWY62_00720) comYC 118087..118368 (+) 282 WP_024395447.1 competence type IV pilus major pilin ComGC Machinery gene
  KWY62_RS00725 (KWY62_00725) comGD 118349..118756 (+) 408 WP_024395446.1 competence type IV pilus minor pilin ComGD -
  KWY62_RS00730 (KWY62_00730) comYE 118728..119021 (+) 294 WP_002936548.1 competence type IV pilus minor pilin ComGE Machinery gene
  KWY62_RS00735 (KWY62_00735) comGF/cglF 119008..119442 (+) 435 WP_024395445.1 competence type IV pilus minor pilin ComGF Machinery gene
  KWY62_RS00740 (KWY62_00740) comGG 119420..119830 (+) 411 WP_024395444.1 competence type IV pilus minor pilin ComGG -
  KWY62_RS00745 (KWY62_00745) comYH 119887..120840 (+) 954 WP_044776365.1 class I SAM-dependent methyltransferase Machinery gene
  KWY62_RS00750 (KWY62_00750) - 120890..122077 (+) 1188 WP_014637319.1 acetate kinase -
  KWY62_RS00755 (KWY62_00755) - 122338..122889 (+) 552 WP_014637320.1 folate family ECF transporter S component -

Sequence

Protein


Download         Length: 97 a.a.        Molecular weight: 10746.66 Da        Isoelectric Point: 10.2088

>NTDB_id=588139 KWY62_RS00730 WP_002936548.1 118728..119021(+) (comYE) [Streptococcus suis strain ID41570]
MVAIRKQKNKAYILLESLVALATLVTICSLILSAVDAGRRRQAWELEQQEVLNLAQMAVQTGQDNLALNGVTVQVQRTAD
KIIVFREGKEVLSVVKK

Nucleotide


Download         Length: 294 bp        

>NTDB_id=588139 KWY62_RS00730 WP_002936548.1 118728..119021(+) (comYE) [Streptococcus suis strain ID41570]
GTGGTCGCTATAAGAAAACAGAAGAATAAGGCTTATATTTTGCTAGAAAGTCTGGTTGCCCTTGCGACTCTAGTGACCAT
TTGTAGCTTGATTTTATCAGCTGTGGATGCAGGTCGTAGGCGACAGGCTTGGGAATTGGAACAACAGGAGGTTCTCAATC
TAGCACAGATGGCTGTTCAGACCGGGCAAGATAACCTAGCCTTAAACGGTGTTACAGTTCAGGTTCAACGAACTGCGGAT
AAGATTATTGTTTTCCGCGAGGGAAAGGAGGTTTTATCGGTTGTTAAAAAGTAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(13-94)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYE Streptococcus mutans UA140

53.608

100

0.536
  comYE Streptococcus mutans UA159

53.608

100

0.536
  comGE/cglE Streptococcus pneumoniae Rx1

40.217

94.845

0.381
  comGE/cglE Streptococcus pneumoniae D39

40.217

94.845

0.381
  comGE/cglE Streptococcus pneumoniae R6

40.217

94.845

0.381
  comGE/cglE Streptococcus pneumoniae TIGR4

40.217

94.845

0.381
  comGE/cglE Streptococcus mitis SK321

39.13

94.845

0.371
  comGE/cglE Streptococcus mitis NCTC 12261

39.13

94.845

0.371