Detailed information NTG0058635

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: TL13_RS05655
• Genome accession: NC_021213
• Coordinates: 1145605..1147842 (-)
• Length: 745 a.a.
• NCBI ID: WP_041179393.1
• Uniprot ID: -
• Organism: Streptococcus suis TL13
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1140605..1152842

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
TL13_RS05630 (TL13_1118)	tmk	1140721..1141359 (-)	639	WP_015646956.1	dTMP kinase	-
TL13_RS05635 (TL13_1119)	-	1141534..1142400 (+)	867	WP_015646957.1	YitT family protein	-
TL13_RS05640 (TL13_1120)	-	1142437..1143708 (-)	1272	WP_015646958.1	toxic anion resistance protein	-
TL13_RS05645 (TL13_1121)	-	1143714..1144541 (-)	828	WP_015646959.1	hypothetical protein	-
TL13_RS05650 (TL13_1122)	-	1144635..1145291 (-)	657	WP_015646960.1	CBS domain-containing protein	-
TL13_RS10890	-	1145474..1145596 (-)	123	Protein_1066	IS982 family transposase	-
TL13_RS05655 (TL13_1123)	comEC/celB	1145605..1147842 (-)	2238	WP_041179393.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
TL13_RS05660 (TL13_1124)	comEA/celA/cilE	1147826..1148488 (-)	663	WP_015646962.1	helix-hairpin-helix domain-containing protein	Machinery gene
TL13_RS05665 (TL13_1125)	-	1148555..1149301 (-)	747	WP_014735985.1	lysophospholipid acyltransferase family protein	-
TL13_RS05670 (TL13_1126)	-	1149448..1150893 (+)	1446	WP_015646963.1	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase	-
TL13_RS05675 (TL13_1127)	-	1151045..1151830 (+)	786	WP_014636900.1	ABC transporter ATP-binding protein	-
TL13_RS05680 (TL13_1128)	-	1151843..1152772 (+)	930	WP_015646964.1	ABC transporter substrate-binding protein	-

Sequence

Protein

• Length: 745 a.a.
• Molecular weight: 83859.77 Da
• Isoelectric Point: 8.2224

>NTDB_id=58635 TL13_RS05655 WP_041179393.1 1145605..1147842(-) (comEC/celB) [Streptococcus suis TL13]
MSRSIKLPCQPIHLALLAVAVYFAVHSFSLLTIGLLSLVLTVFGVRQGKTVFLKTLPLLALCGLFFGYQKVQWERADQSA
PEQVTTVQVIPDTIDINGDSLSFRGRADGQTYQVFYKLTSQEEQAYFQKLANLVQLEVEAEVSLPAGQRNFKGFDYQAYL
KTQGIYRTVKITVIKKIVPVQSRNVFDWLSSWRRQALVYVKTNFPAPMSHYMTGLLFGDLDSDFDQMSDLYSSLGIIHLF
ALSGMQVGFFIDKFRWILLRLGLTKEAVDKLQIPFSLFYAGLTGFSVSVVRSLVQKILGNLGLRKLDNFAVTVFVCLLIL
PRFLLTAGGILTFTYAFLLTVFDFEDLGRVKKVAVESLSISLGILPVLMTYFYAFQPLSILLTVVFSFVFDVLLLPGLSV
IFLLSPLVKITWVNGFFVFMEKIIVWVADLGFRPWILGQPSGVILVLLLVSLFLLYDFHRKKKWLLGLSLVLALLFFITK
HPLENEVTVVDIGQGDSIFLRDMRGRTVLIDVGGRVDFAVEEAWQERSSQANAERTLIPYLHSRGVDRIDSLVLTHTDTD
HVGDVLEVAKQVQIGRIVVSPGSLTVPDFVATLKKINVPVHVVKVGDRLPIFDSYLEVLYPDGTGDGGNNDSIVLYGRLL
ETNFLFTGDLEQGELDLIATYPNLPVDVLKAGHHGSKGSSYPEFLDHIGAKIALISAGENNRYKHPHQETLDRFDSRNIQ
VYRTDQQGAIRFRGWKEWRIETVRR

Nucleotide

• Length: 2238 bp

>NTDB_id=58635 TL13_RS05655 WP_041179393.1 1145605..1147842(-) (comEC/celB) [Streptococcus suis TL13]
ATGTCACGGTCGATTAAGCTCCCCTGCCAGCCCATCCACTTGGCTCTTTTGGCAGTTGCGGTCTACTTTGCAGTCCACTC
TTTTTCCCTGTTGACAATAGGCCTACTCAGTTTGGTGTTAACTGTCTTTGGTGTTCGGCAAGGTAAGACAGTTTTCCTCA
AAACGCTGCCGCTTCTAGCCCTATGTGGCTTGTTTTTCGGCTACCAAAAGGTCCAATGGGAGCGGGCAGACCAGTCAGCC
CCAGAGCAAGTCACAACTGTTCAGGTCATTCCAGATACCATAGACATCAATGGCGACAGCTTGTCTTTTCGTGGTCGGGC
TGACGGACAAACCTATCAGGTTTTCTATAAATTAACCAGTCAGGAGGAGCAGGCTTATTTTCAAAAGCTGGCAAACCTGG
TCCAGCTAGAAGTGGAAGCAGAGGTCAGCCTGCCAGCTGGTCAGCGGAATTTCAAGGGCTTTGACTATCAGGCCTATCTG
AAAACACAGGGCATCTATCGGACAGTCAAGATTACGGTAATCAAGAAGATTGTCCCTGTTCAGTCTAGGAATGTTTTTGA
CTGGTTGTCAAGCTGGCGGAGGCAGGCTTTAGTTTATGTCAAAACCAATTTTCCGGCTCCCATGAGCCACTACATGACAG
GGCTCTTGTTTGGGGACTTGGATAGTGATTTTGACCAGATGAGTGACCTCTATTCCAGTTTGGGTATCATTCATCTCTTT
GCCCTGTCTGGTATGCAGGTGGGCTTTTTCATCGACAAGTTTCGCTGGATTTTGTTGCGTCTGGGCTTGACCAAGGAAGC
CGTAGATAAGTTGCAGATTCCCTTTTCACTTTTTTATGCTGGTTTGACAGGCTTTTCTGTGTCGGTGGTGCGGTCCTTGG
TCCAAAAAATTCTGGGTAATCTAGGCTTGCGGAAGTTGGATAACTTTGCGGTGACAGTCTTTGTCTGTCTGCTGATACTA
CCCCGATTTTTACTGACAGCAGGAGGTATCCTGACCTTTACCTATGCTTTCTTGCTGACGGTCTTTGATTTTGAGGATTT
GGGGCGGGTCAAAAAGGTTGCGGTGGAGAGCCTCAGTATTTCACTGGGAATTTTGCCGGTGCTTATGACCTATTTCTATG
CCTTTCAGCCTCTATCTATCCTCTTGACCGTTGTCTTTTCCTTTGTCTTTGATGTCCTGCTCTTGCCAGGATTATCGGTC
ATTTTTCTTCTATCTCCCTTGGTCAAGATTACTTGGGTCAACGGATTTTTTGTATTTATGGAAAAAATCATTGTCTGGGT
GGCGGATTTGGGATTTCGGCCTTGGATACTGGGCCAGCCGTCTGGGGTAATTCTTGTTCTCTTGCTAGTCAGCCTCTTCT
TACTCTATGATTTTCACAGGAAGAAAAAATGGTTATTAGGACTGAGCTTGGTCCTTGCTCTGCTATTTTTCATAACCAAA
CACCCGCTGGAAAACGAGGTGACGGTGGTGGACATCGGGCAGGGGGACAGCATCTTTTTGCGGGATATGCGGGGGCGGAC
GGTCCTGATAGATGTGGGCGGACGAGTCGATTTCGCGGTCGAGGAAGCGTGGCAGGAGCGGTCTTCGCAGGCAAATGCAG
AGCGGACTTTGATTCCCTATCTGCATAGTCGGGGTGTGGATAGGATTGATAGTCTAGTGCTGACGCACACCGACACAGAC
CATGTGGGTGATGTGCTGGAAGTGGCTAAGCAGGTGCAAATTGGTCGGATTGTCGTGTCGCCGGGAAGTCTGACGGTGCC
TGACTTTGTAGCGACCTTGAAAAAAATCAATGTTCCTGTCCATGTGGTAAAAGTGGGCGACCGCCTACCAATTTTTGACT
CCTATCTGGAGGTCCTCTATCCAGACGGGACAGGCGACGGTGGCAATAATGACTCTATTGTTCTCTACGGTCGCTTGTTG
GAAACCAACTTTCTCTTTACAGGAGATTTGGAGCAAGGGGAGTTGGACTTGATAGCAACCTATCCCAACCTGCCTGTCGA
TGTCCTCAAGGCTGGTCACCATGGCTCCAAAGGTTCTTCCTATCCCGAATTTTTAGACCATATCGGTGCCAAGATTGCCT
TGATATCTGCTGGAGAAAATAACCGCTACAAGCATCCTCATCAAGAAACCTTGGACCGCTTTGACAGTCGGAATATCCAA
GTCTATCGTACCGACCAGCAAGGAGCCATCCGCTTCCGAGGTTGGAAGGAGTGGAGGATTGAAACGGTGAGGAGGTAA

Domains

Predicted by InterproScan.

• Metallo-beta-lactamase superfamily (Lactamase_B) (493-698)

• Domain of unknown function (DUF4131) (DUF4131) (29-172)

• Competence protein (Competence) (215-460)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	54.459	99.329	0.541
comEC/celB	Streptococcus mitis NCTC 12261	53.469	98.658	0.528
comEC/celB	Streptococcus pneumoniae TIGR4	52.446	98.792	0.518
comEC/celB	Streptococcus pneumoniae Rx1	52.174	98.792	0.515
comEC/celB	Streptococcus pneumoniae D39	52.174	98.792	0.515
comEC/celB	Streptococcus pneumoniae R6	52.174	98.792	0.515
comEC	Lactococcus lactis subsp. cremoris KW2	48.996	100	0.491