Detailed information NTG0586273

Bioinformatically predicted

Overview

• Name: ciaR
• Type: Regulator
• Locus tag: KV238_RS08190
• Genome accession: NZ_CP078012
• Coordinates: 1690196..1690870 (+)
• Length: 224 a.a.
• NCBI ID: WP_043983576.1
• Uniprot ID: -
• Organism: Streptococcus equi subsp. zooepidemicus strain SEZ_18-036
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1685196..1695870

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KV238_RS08175 (KV238_08165)	pstB	1685520..1686278 (+)	759	WP_012678019.1	phosphate ABC transporter ATP-binding protein PstB	-
KV238_RS08180 (KV238_08170)	phoU	1686349..1687002 (+)	654	WP_012678018.1	phosphate signaling complex protein PhoU	-
KV238_RS08185 (KV238_08175)	-	1687232..1689769 (+)	2538	WP_043983578.1	M1 family metallopeptidase	-
KV238_RS08190 (KV238_08180)	ciaR	1690196..1690870 (+)	675	WP_043983576.1	response regulator transcription factor	Regulator
KV238_RS08195 (KV238_08185)	ciaH	1690863..1692173 (+)	1311	WP_159334696.1	sensor histidine kinase	Regulator
KV238_RS08200 (KV238_08190)	-	1692556..1692990 (+)	435	WP_043030769.1	hypothetical protein	-
KV238_RS08205 (KV238_08195)	-	1692991..1693236 (+)	246	WP_043030765.1	hypothetical protein	-
KV238_RS08210 (KV238_08200)	-	1693252..1693659 (+)	408	WP_014622815.1	hypothetical protein	-
KV238_RS08215 (KV238_08205)	-	1693669..1693959 (+)	291	WP_021320713.1	hypothetical protein	-
KV238_RS08220 (KV238_08210)	-	1693883..1694266 (+)	384	WP_012678013.1	hypothetical protein	-
KV238_RS08225 (KV238_08215)	-	1694268..1694519 (+)	252	WP_012678012.1	hypothetical protein	-
KV238_RS08230 (KV238_08220)	-	1694695..1695075 (+)	381	WP_042670594.1	hypothetical protein	-
KV238_RS08235 (KV238_08225)	-	1695072..1695332 (+)	261	WP_021320716.1	hypothetical protein	-
KV238_RS08240 (KV238_08230)	-	1695348..1695761 (+)	414	WP_230923512.1	hypothetical protein	-

Sequence

Protein

• Length: 224 a.a.
• Molecular weight: 25527.50 Da
• Isoelectric Point: 4.5644

>NTDB_id=586273 KV238_RS08190 WP_043983576.1 1690196..1690870(+) (ciaR) [Streptococcus equi subsp. zooepidemicus strain SEZ_18-036]
MIKLLLVEDDLSLSNSIFDFLDDFADVTQVFDGDEGLYEAESGIYDLILLDLMLPEKDGFQVLKALREKDIKIPVLIMTA
KESIDDKGHGFELGADDYLTKPFYLEELKMRIQALLKRVGKFNDKSLKFGNLTVDTTRKEVQVNGQAIELLGKELDLLVY
ILQNQNVILPKSQIFDRIWGFDSDTTISVVEVYVSKIRKKLKGTDFVNHLQTLRSVGYILKANE

Nucleotide

• Length: 675 bp

>NTDB_id=586273 KV238_RS08190 WP_043983576.1 1690196..1690870(+) (ciaR) [Streptococcus equi subsp. zooepidemicus strain SEZ_18-036]
ATGATAAAACTATTATTAGTAGAAGACGATTTAAGCTTGTCAAATTCTATCTTTGATTTTTTAGATGACTTTGCTGATGT
GACGCAGGTTTTTGATGGTGACGAAGGACTCTATGAGGCAGAAAGCGGTATTTATGATTTGATTCTGTTAGATTTGATGC
TGCCTGAAAAGGATGGCTTTCAAGTGTTAAAAGCCTTACGTGAAAAAGACATCAAAATTCCCGTCTTGATCATGACTGCC
AAAGAAAGCATCGATGACAAAGGGCATGGCTTTGAGCTTGGTGCTGATGACTATTTAACCAAGCCCTTTTACCTAGAAGA
ATTAAAAATGCGGATTCAGGCCTTGCTTAAGCGCGTAGGAAAGTTTAATGACAAGAGCCTTAAATTTGGCAACCTGACTG
TAGATACTACCCGTAAAGAGGTACAGGTCAATGGGCAGGCCATAGAGCTATTAGGCAAGGAGCTTGATTTACTAGTCTAT
ATTCTTCAAAATCAAAATGTTATTTTGCCAAAGTCACAAATTTTTGATCGTATCTGGGGCTTTGATAGTGATACCACTAT
CTCTGTTGTAGAGGTCTATGTCTCTAAAATCCGTAAGAAGCTTAAGGGGACAGACTTTGTTAATCATCTTCAAACCTTGA
GAAGTGTAGGATATATCTTAAAAGCTAATGAATAA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (5-112)

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (145-220)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ciaR	Streptococcus mutans UA159	85.068	98.661	0.839
ciaR	Streptococcus pneumoniae Rx1	80.995	98.661	0.799
ciaR	Streptococcus pneumoniae D39	80.995	98.661	0.799
ciaR	Streptococcus pneumoniae R6	80.995	98.661	0.799
ciaR	Streptococcus pneumoniae TIGR4	80.995	98.661	0.799
covR	Lactococcus lactis subsp. lactis strain DGCC12653	38.428	100	0.393
covR	Streptococcus salivarius strain HSISS4	35.841	100	0.362