Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   TL13_RS03230 Genome accession   NC_021213
Coordinates   641855..642559 (+) Length   234 a.a.
NCBI ID   WP_015646623.1    Uniprot ID   A0A075SQ08
Organism   Streptococcus suis TL13     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 636855..647559
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  TL13_RS03210 (TL13_0633) - 638663..639322 (-) 660 WP_014637676.1 amino acid ABC transporter permease -
  TL13_RS03215 (TL13_0634) - 639337..640035 (-) 699 WP_015646621.1 amino acid ABC transporter permease -
  TL13_RS03220 (TL13_0635) - 640050..640889 (-) 840 WP_015646622.1 transporter substrate-binding domain-containing protein -
  TL13_RS03225 (TL13_0636) - 640900..641661 (-) 762 WP_002935839.1 amino acid ABC transporter ATP-binding protein -
  TL13_RS03230 (TL13_0637) micA 641855..642559 (+) 705 WP_015646623.1 response regulator YycF Regulator
  TL13_RS03235 (TL13_0638) micB 642552..643901 (+) 1350 WP_002935841.1 cell wall metabolism sensor histidine kinase VicK Regulator
  TL13_RS03240 (TL13_0639) vicX 643908..644711 (+) 804 WP_002935843.1 MBL fold metallo-hydrolase Regulator
  TL13_RS03245 (TL13_0641) - 645446..646648 (-) 1203 WP_079266783.1 IS110 family transposase -
  TL13_RS03250 (TL13_0642) - 646927..647481 (+) 555 WP_015646626.1 ATP-binding cassette domain-containing protein -

Sequence

Protein


Download         Length: 234 a.a.        Molecular weight: 26781.84 Da        Isoelectric Point: 4.8957

>NTDB_id=58623 TL13_RS03230 WP_015646623.1 641855..642559(+) (micA) [Streptococcus suis TL13]
MKKILIVDDEKPISDIIKFNMTREGYEVVTAFDGREALEVFEAEFPDIVILDLMLPELDGLEVARMIRKTSNVPILMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELQARVKALLRRSELAETQTNIESTGTPELVIGDLVILPDAFVAKKHGKELELT
HREFELLHHLAKHLGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDAPSRPEYILTRRGVGYFIKGND

Nucleotide


Download         Length: 705 bp        

>NTDB_id=58623 TL13_RS03230 WP_015646623.1 641855..642559(+) (micA) [Streptococcus suis TL13]
ATGAAAAAAATATTAATTGTAGATGATGAAAAACCAATCTCAGATATTATTAAGTTTAATATGACTCGTGAGGGATATGA
AGTTGTGACAGCTTTCGATGGACGTGAAGCCTTGGAAGTGTTTGAGGCTGAGTTTCCTGACATTGTCATTTTGGACTTGA
TGCTGCCAGAATTGGATGGACTGGAGGTTGCTCGAATGATTCGTAAGACCAGCAATGTTCCAATCTTGATGTTATCTGCT
AAAGATAGCGAATTTGATAAGGTTATCGGACTTGAAATAGGGGCGGATGATTATGTGACCAAGCCCTTCTCTAATCGCGA
ATTGCAGGCGCGTGTTAAGGCTCTTCTTCGCCGTAGTGAATTGGCAGAGACGCAGACAAATATTGAGTCAACAGGAACTC
CAGAGTTGGTGATTGGCGATTTGGTCATTCTGCCTGATGCGTTTGTCGCTAAGAAGCATGGCAAAGAGCTGGAGCTGACC
CATCGTGAGTTTGAATTGCTCCACCATCTGGCCAAACACTTAGGTCAGGTTATGACTCGAGAACATCTATTGGAAACAGT
TTGGGGTTATGATTACTTTGGTGATGTCCGCACGGTGGATGTAACGATTCGTCGTCTGCGTGAGAAAATTGAAGATGCAC
CAAGCAGACCAGAATACATTCTTACTCGTCGCGGAGTGGGATATTTTATAAAAGGAAATGATTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-229)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A075SQ08

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

81.116

99.573

0.808
  vicR Streptococcus mutans UA159

80

100

0.803
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.783

98.291

0.44
  covR Streptococcus salivarius strain HSISS4

43.723

98.718

0.432
  scnR Streptococcus mutans UA159

38.095

98.718

0.376

Multiple sequence alignment