Detailed information NTG0586226

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: KV238_RS00885
• Genome accession: NZ_CP078012
• Coordinates: 186220..188376 (+)
• Length: 718 a.a.
• NCBI ID: WP_230923701.1
• Uniprot ID: -
• Organism: Streptococcus equi subsp. zooepidemicus strain SEZ_18-036
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 181220..193376

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KV238_RS00840 (KV238_00835)	-	181291..181530 (+)	240	WP_043984241.1	helix-turn-helix domain-containing protein	-
KV238_RS00845 (KV238_00840)	-	181632..182213 (-)	582	WP_165627810.1	GNAT family N-acetyltransferase	-
KV238_RS00850 (KV238_00845)	-	182464..182865 (-)	402	WP_230923698.1	bacteriocin immunity protein	-
KV238_RS00855 (KV238_00850)	-	183539..183742 (-)	204	WP_012516109.1	Blp family class II bacteriocin	-
KV238_RS00860 (KV238_00855)	-	183759..184013 (-)	255	WP_012516110.1	Blp family class II bacteriocin	-
KV238_RS00865 (KV238_00860)	-	184742..185038 (-)	297	WP_230923699.1	bacteriocin immunity protein	-
KV238_RS00870 (KV238_00865)	-	185045..185293 (-)	249	WP_230923700.1	garvicin Q family class II bacteriocin	-
KV238_RS00875 (KV238_00870)	-	185446..185742 (-)	297	WP_043030063.1	bacteriocin immunity protein	-
KV238_RS00880 (KV238_00875)	-	185742..185960 (-)	219	WP_021321057.1	leucocin A/sakacin P family class II bacteriocin	-
KV238_RS00885 (KV238_00880)	comA/nlmT	186220..188376 (+)	2157	WP_230923701.1	peptide cleavage/export ABC transporter	Regulator
KV238_RS00890 (KV238_00885)	-	188387..189745 (+)	1359	WP_230923702.1	bacteriocin secretion accessory protein	-
KV238_RS00895 (KV238_00890)	-	189845..189979 (+)	135	WP_012516117.1	ComC/BlpC family leader-containing pheromone/bacteriocin	-
KV238_RS00900 (KV238_00895)	-	190097..191431 (-)	1335	WP_230923703.1	sensor histidine kinase	-
KV238_RS00905 (KV238_00900)	comE/blpR	191431..192180 (-)	750	WP_111690344.1	LytR/AlgR family response regulator transcription factor	Regulator
KV238_RS00910 (KV238_00905)	-	192813..193007 (-)	195	WP_038674052.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
KV238_RS00915 (KV238_00910)	-	193024..193281 (-)	258	WP_043030068.1	Blp family class II bacteriocin	-

Sequence

Protein

• Length: 718 a.a.
• Molecular weight: 80589.75 Da
• Isoelectric Point: 7.4612

>NTDB_id=586226 KV238_RS00885 WP_230923701.1 186220..188376(+) (comA/nlmT) [Streptococcus equi subsp. zooepidemicus strain SEZ_18-036]
MTLFYKRTFVPQIDARDCGVAALASIARYYGSDYSLAYLRELAKTNKEGTTALGIVMAAKEMGFETRPIQADMTLFDMAD
VPYPLIVHVNKEGKLQHYYVVYKSKKDYLIIGDPDPMVKVTKMSKERFASEWTGVTICLAPKPNYKPHKDQKNGLLGFFP
LIFKQRALIFYIVLASVLVTVINISGSYYLQGILDEYIPNQLKSTLGIVSIGLIITYILQQLMSFSRDYLLTVLSQRLTI
DVILSYIRHIFELPMSFFATRRTGEVTSRFTDANSIIDALASTILSLFLDLSILAIVGSVLLVQNSRLFLLSLISIPVYT
LIICAFIKPFEQMNHDVMQSNAMLSSAIIEDINGIETIKSLTSEENRYQKIDSDFVDYLDKSFKLSKYTILQATLKQGAQ
LILNIIILWFGAQLVINGKISIGQLITFNTLLAYFTTPLENIINLQTKLQAAKVANNRLNEVYLVESEFKASQALYDLSL
LQGDIQFEAVSYRYGFGKDTLSDITLTIKQGAKVTLVGVSGSGKTTLAKMLVNFFEPYKGRITINQNDLKTIDKKNLRQY
INYLPQQAYIFNGSILENLTLGAKQGISQEDILNACEIADIRHDIEQMPMGYQTELSDGAGLSGGQKQRIALARALLTQA
PILVLDEATSGLDILTEKKIIDRLMNMTDKTIIFVAHRLSIAERTDQVVVLNQGQIIETGSHQELMKQGGFYYHLFSE

Nucleotide

• Length: 2157 bp

>NTDB_id=586226 KV238_RS00885 WP_230923701.1 186220..188376(+) (comA/nlmT) [Streptococcus equi subsp. zooepidemicus strain SEZ_18-036]
ATGACACTCTTTTATAAAAGAACCTTTGTACCACAAATAGATGCCAGAGATTGTGGCGTAGCTGCTCTAGCCTCAATCGC
AAGGTATTATGGTTCAGATTATTCATTAGCTTATTTGAGAGAATTAGCAAAGACCAATAAGGAAGGGACAACAGCCCTCG
GTATTGTCATGGCTGCTAAGGAAATGGGGTTTGAAACCAGACCTATTCAAGCGGATATGACCCTCTTTGACATGGCAGAC
GTGCCCTATCCATTGATCGTCCATGTCAATAAAGAAGGAAAGCTACAGCACTACTATGTGGTCTACAAATCTAAAAAAGA
CTATCTTATCATTGGTGATCCCGATCCAATGGTCAAGGTCACAAAAATGTCCAAGGAACGCTTTGCTTCTGAATGGACAG
GTGTCACCATATGCCTTGCTCCTAAGCCAAATTATAAACCACATAAAGACCAAAAAAATGGACTATTAGGCTTCTTTCCG
CTTATTTTTAAACAGCGAGCCCTTATATTTTATATCGTGTTAGCTTCTGTCTTGGTAACGGTCATTAATATTTCTGGTTC
ATACTATCTCCAAGGGATTTTAGACGAGTATATTCCAAATCAGCTGAAATCTACCTTAGGGATTGTATCAATTGGTCTCA
TCATTACCTATATACTCCAGCAGCTAATGAGCTTTTCTAGAGATTATCTTTTAACTGTCCTTAGCCAACGTCTTACGATT
GATGTGATCCTGTCCTATATCCGCCATATTTTCGAATTGCCGATGTCCTTTTTTGCAACACGTCGAACAGGTGAGGTAAC
CTCGCGCTTTACAGATGCTAACTCTATCATTGACGCACTCGCTTCAACCATTTTATCCCTCTTTCTAGACCTCTCTATAT
TAGCTATTGTCGGAAGTGTTCTTTTGGTGCAAAATAGCAGGCTTTTTCTGCTATCTCTGATTTCTATCCCAGTATATACC
CTTATCATATGTGCCTTTATAAAGCCGTTTGAACAAATGAATCATGATGTGATGCAAAGCAATGCCATGCTAAGCTCTGC
TATTATCGAAGATATCAACGGGATCGAAACCATAAAATCACTAACCAGTGAAGAAAACCGTTACCAAAAAATTGACAGCG
ACTTTGTGGATTACCTTGATAAGTCTTTTAAGCTTAGTAAATATACCATCTTACAAGCCACACTTAAGCAAGGAGCGCAG
CTAATTCTGAATATCATCATTCTTTGGTTTGGGGCTCAACTGGTCATTAATGGTAAAATTTCAATCGGGCAATTAATTAC
CTTTAACACACTTCTTGCCTATTTTACAACCCCTTTAGAAAATATCATTAATCTTCAAACCAAGCTCCAAGCAGCTAAGG
TTGCCAATAATCGTCTCAATGAGGTCTATCTTGTAGAGTCCGAATTTAAAGCCTCGCAAGCCTTATACGATTTATCGCTC
TTACAGGGTGACATTCAGTTTGAAGCTGTTTCCTACAGGTATGGCTTTGGCAAGGATACATTATCAGATATTACATTAAC
CATTAAGCAGGGAGCAAAAGTAACCCTTGTTGGTGTCAGCGGCTCAGGAAAAACAACCCTAGCCAAGATGCTCGTCAATT
TCTTTGAACCTTATAAGGGACGTATAACCATCAACCAAAACGATCTCAAGACCATTGATAAAAAGAATCTTCGACAATAC
ATCAACTACCTTCCACAACAAGCCTATATCTTTAATGGATCTATCTTAGAAAATCTAACCTTGGGAGCCAAGCAAGGCAT
CAGCCAGGAAGACATTCTTAACGCCTGTGAGATTGCTGACATTCGTCACGACATCGAGCAAATGCCAATGGGATACCAAA
CCGAGCTCTCTGATGGGGCTGGCTTATCTGGCGGACAAAAACAGAGAATTGCACTTGCTAGAGCATTACTAACCCAAGCT
CCTATACTAGTTCTTGATGAAGCAACCAGCGGACTTGACATACTGACAGAAAAGAAAATCATTGACCGTCTCATGAACAT
GACAGACAAAACGATTATTTTCGTTGCCCACCGGCTTAGTATCGCAGAGCGCACTGATCAGGTTGTGGTTCTTAATCAAG
GGCAAATCATTGAAACAGGCAGCCACCAGGAATTAATGAAACAAGGTGGATTTTATTACCACCTATTTAGTGAATAA

Domains

Predicted by InterproScan.

• Peptidase C39 family (Peptidase_C39) (8-143)

• ABC transporter (ABC_tran) (501-650)

• ABC transporter transmembrane region (ABC_membrane) (169-439)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	71.13	99.861	0.71
comA	Streptococcus mitis SK321	67.602	99.304	0.671
comA	Streptococcus mitis NCTC 12261	67.321	99.304	0.669
comA	Streptococcus pneumoniae Rx1	66.9	99.304	0.664
comA	Streptococcus pneumoniae D39	66.9	99.304	0.664
comA	Streptococcus pneumoniae R6	66.9	99.304	0.664
comA	Streptococcus pneumoniae TIGR4	66.62	99.304	0.662
comA	Streptococcus gordonii str. Challis substr. CH1	65.498	99.304	0.65