Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   KV238_RS00905 Genome accession   NZ_CP078012
Coordinates   191431..192180 (-) Length   249 a.a.
NCBI ID   WP_111690344.1    Uniprot ID   -
Organism   Streptococcus equi subsp. zooepidemicus strain SEZ_18-036     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 186431..197180
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KV238_RS00890 (KV238_00885) - 188387..189745 (+) 1359 WP_230923702.1 bacteriocin secretion accessory protein -
  KV238_RS00895 (KV238_00890) - 189845..189979 (+) 135 WP_012516117.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  KV238_RS00900 (KV238_00895) - 190097..191431 (-) 1335 WP_230923703.1 sensor histidine kinase -
  KV238_RS00905 (KV238_00900) comE/blpR 191431..192180 (-) 750 WP_111690344.1 LytR/AlgR family response regulator transcription factor Regulator
  KV238_RS00910 (KV238_00905) - 192813..193007 (-) 195 WP_038674052.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  KV238_RS00915 (KV238_00910) - 193024..193281 (-) 258 WP_043030068.1 Blp family class II bacteriocin -
  KV238_RS00920 (KV238_00915) rlmD 193602..194969 (-) 1368 WP_230923704.1 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD -
  KV238_RS00925 (KV238_00920) - 194966..195934 (-) 969 WP_012516123.1 helix-hairpin-helix domain-containing protein -
  KV238_RS00930 (KV238_00925) recX 195998..196774 (+) 777 WP_165626240.1 recombination regulator RecX -

Sequence

Protein


Download         Length: 249 a.a.        Molecular weight: 29217.65 Da        Isoelectric Point: 8.4602

>NTDB_id=586227 KV238_RS00905 WP_111690344.1 191431..192180(-) (comE/blpR) [Streptococcus equi subsp. zooepidemicus strain SEZ_18-036]
MRVVILEDDMIQQRYLEKLIKELEVKHQLLFQGLDCFGRSHQLLSAIKKNCGQQLFFLDIEIKNEDKKGLEVARQIRQIN
PDAMIVFVTTHSEFMPLAFQYQVSALDYIDKELPHTEFVQRVETALLYAVRQNSETIAESAFYFTSRYAQVQVPFNDILY
IETSSRAHRVNLYTKKERMQFTGTLTDILKQESRFLQCHRSFLINPRNVVRVDKIERVVYFRNGSSCLIARSKMNSVLTT
IENLHRGDN

Nucleotide


Download         Length: 750 bp        

>NTDB_id=586227 KV238_RS00905 WP_111690344.1 191431..192180(-) (comE/blpR) [Streptococcus equi subsp. zooepidemicus strain SEZ_18-036]
GTGAGAGTAGTTATTTTAGAAGATGATATGATTCAGCAGAGATATTTAGAAAAGCTCATTAAAGAGCTTGAGGTTAAGCA
CCAGCTATTATTTCAAGGACTTGACTGTTTTGGAAGGTCTCACCAGCTATTAAGTGCTATCAAGAAGAACTGTGGTCAGC
AGCTATTCTTTTTAGATATTGAGATAAAAAATGAGGACAAAAAAGGGCTTGAGGTTGCTAGGCAAATTCGTCAGATAAAT
CCAGATGCGATGATTGTTTTTGTAACGACTCACTCGGAATTTATGCCCTTGGCTTTTCAGTATCAGGTATCTGCTTTGGA
CTATATCGATAAAGAGCTGCCTCACACTGAGTTTGTTCAACGGGTAGAGACTGCTTTATTATATGCTGTGCGGCAAAATA
GTGAAACGATAGCGGAAAGTGCTTTTTATTTTACATCTCGTTATGCTCAGGTACAGGTGCCTTTTAATGATATCCTGTAT
ATTGAGACATCGTCACGAGCGCATCGTGTCAATTTGTATACAAAAAAGGAGAGAATGCAATTTACAGGGACTTTGACGGA
TATTTTGAAGCAAGAGTCTCGTTTTTTGCAATGTCATCGTTCTTTTTTGATTAATCCTAGGAATGTCGTTAGGGTAGATA
AGATTGAGCGAGTGGTTTATTTTCGAAATGGCTCTAGCTGCTTAATTGCTCGTAGTAAAATGAACAGTGTTTTAACAACA
ATTGAGAACCTACATAGAGGAGATAATTAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-122)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

52.209

100

0.522
  comE/comE1 Streptococcus equinus JB1

40.586

95.984

0.39
  comE/comE2 Streptococcus equinus JB1

36.29

99.598

0.361