Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   KVP03_RS09555 Genome accession   NZ_CP077959
Coordinates   2016654..2018810 (+) Length   718 a.a.
NCBI ID   WP_230923089.1    Uniprot ID   -
Organism   Streptococcus equi subsp. zooepidemicus strain SEZ_14-145     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 2011654..2023810
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KVP03_RS09510 (KVP03_09490) - 2011736..2011975 (+) 240 WP_230923088.1 helix-turn-helix domain-containing protein -
  KVP03_RS09515 (KVP03_09495) - 2012067..2012657 (-) 591 WP_111692690.1 GNAT family N-acetyltransferase -
  KVP03_RS09520 (KVP03_09500) - 2012907..2013320 (-) 414 WP_012679937.1 hypothetical protein -
  KVP03_RS09525 (KVP03_09505) - 2013983..2014186 (-) 204 WP_012516109.1 Blp family class II bacteriocin -
  KVP03_RS09530 (KVP03_09510) - 2014203..2014457 (-) 255 WP_111692691.1 Blp family class II bacteriocin -
  KVP03_RS09535 (KVP03_09515) - 2014611..2014907 (-) 297 WP_111692692.1 bacteriocin immunity protein -
  KVP03_RS09540 (KVP03_09520) - 2014907..2015125 (-) 219 WP_037579371.1 leucocin A/sakacin P family class II bacteriocin -
  KVP03_RS09545 (KVP03_09525) - 2015843..2016139 (-) 297 WP_111692935.1 bacteriocin immunity protein -
  KVP03_RS09550 (KVP03_09530) - 2016146..2016394 (-) 249 WP_111692693.1 garvicin Q family class II bacteriocin -
  KVP03_RS09555 (KVP03_09535) comA/nlmT 2016654..2018810 (+) 2157 WP_230923089.1 peptide cleavage/export ABC transporter Regulator
  KVP03_RS09560 (KVP03_09540) - 2018821..2020179 (+) 1359 WP_230923090.1 bacteriocin secretion accessory protein -
  KVP03_RS09565 (KVP03_09545) - 2020279..2020413 (+) 135 WP_012516117.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  KVP03_RS10610 (KVP03_09550) - 2020532..2021866 (-) 1335 WP_111692697.1 sensor histidine kinase -
  KVP03_RS09575 (KVP03_09555) comE/blpR 2021866..2022615 (-) 750 WP_042671079.1 LytR/AlgR family response regulator transcription factor Regulator
  KVP03_RS09580 (KVP03_09560) - 2023242..2023445 (-) 204 WP_012516120.1 TmhB bacteriocin enhancer peptide -
  KVP03_RS09585 (KVP03_09565) - 2023462..2023719 (-) 258 WP_111678353.1 Blp family class II bacteriocin -

Sequence

Protein


Download         Length: 718 a.a.        Molecular weight: 80580.71 Da        Isoelectric Point: 7.7849

>NTDB_id=585674 KVP03_RS09555 WP_230923089.1 2016654..2018810(+) (comA/nlmT) [Streptococcus equi subsp. zooepidemicus strain SEZ_14-145]
MTLFYKRTFVPQIDARDCGVAALASIARYYGSDYSLAHLRELAKTNKEGTTALGIVIAAKEIGFETRPIQADMTLFDMAD
VPYPLIVHVNKEGKLQHYYVVYKSKKDYLIIGDPNPMVKVTKMSKERFASEWTGVTICLAPKPNYKPHKDQKNGLLGFFP
LIFKQRALIFYIVLASVLVTIINIAGSYYLQGILDEYIPNQLKSTLGIVSIGLIITYILQQLMSFSRDYLLTVLSQRLTI
DVILSYIRHIFELPMSFFATRRTGEVTSRFTDANSIIDALASTILSLFLDLSILAIVGSVLLVQNSRLFLLSLISIPVYT
LIICAFIKPFEQMNHDVMQSNAMLSSAIIEDINGIETIKSLTSEENRYQKIDSDFVDYLDKSFRLSKYTILQATLKQGAQ
LILNIIILWFGAQLVINGRISIGQLITFNTLLAYFTTPLENIINLQTKLQAAKVANNRLNEVYLVESEFKASQALYDLSL
LQGDIQFEAVSYRYGFGKDTLSDITLTIKQGAKVTLVGVSGSGKTTLAKMLVNFFEPYKGRITINQNDLKTIDKKNLRQY
INYLPQQAYIFNGSILENLTLGAKQGISQEDILNACEIADIRHDIEQMPMGYQTELSDGAGLSGGQKQRIALARALLTQA
PILVLDEATSGLDILTEKKIIDRLMNMTDKTIIFVAHRLSIAERTDQVVVLNQGQIIETGSHQELMKQGGFYYHLFSE

Nucleotide


Download         Length: 2157 bp        

>NTDB_id=585674 KVP03_RS09555 WP_230923089.1 2016654..2018810(+) (comA/nlmT) [Streptococcus equi subsp. zooepidemicus strain SEZ_14-145]
ATGACACTCTTTTATAAAAGAACCTTTGTACCACAAATAGATGCCAGAGATTGTGGCGTAGCTGCTCTAGCTTCGATCGC
AAGGTATTATGGTTCAGATTATTCATTAGCTCATTTGAGAGAATTAGCAAAGACCAATAAGGAAGGGACAACAGCCCTCG
GTATTGTCATAGCTGCTAAGGAAATAGGGTTTGAAACCAGACCCATTCAAGCGGATATGACCCTCTTTGATATGGCAGAT
GTGCCCTATCCATTGATCGTCCATGTCAATAAAGAAGGAAAGCTACAGCACTACTATGTGGTCTACAAATCTAAAAAAGA
CTATCTTATCATTGGTGATCCCAATCCAATGGTCAAGGTCACAAAAATGTCCAAGGAACGCTTTGCTTCAGAATGGACAG
GTGTCACCATATGCCTTGCTCCTAAGCCAAATTATAAACCACATAAAGACCAAAAAAATGGACTATTAGGCTTCTTTCCG
CTTATTTTTAAACAGCGAGCCCTTATTTTTTATATCGTGTTAGCTTCTGTCTTGGTAACGATCATTAATATTGCTGGTTC
ATACTATCTCCAAGGGATTTTAGACGAGTATATTCCAAATCAACTGAAATCTACCTTAGGGATTGTATCAATTGGTCTCA
TCATTACCTATATACTCCAGCAGCTAATGAGCTTTTCTAGAGATTATCTTTTAACTGTCCTTAGCCAACGTCTTACGATT
GATGTGATCCTGTCCTATATCCGCCATATTTTCGAATTGCCGATGTCCTTTTTTGCAACACGTCGAACAGGTGAGGTAAC
CTCGCGCTTTACAGATGCTAACTCTATCATTGACGCACTCGCTTCAACCATTTTATCTCTCTTTCTAGACCTCTCTATAT
TAGCTATTGTCGGAAGTGTTCTTTTGGTGCAAAATAGCAGGCTTTTTCTGCTGTCCCTGATTTCTATTCCAGTATACACC
CTTATCATATGTGCCTTTATAAAGCCGTTTGAACAAATGAATCATGATGTGATGCAAAGCAATGCCATGCTAAGCTCTGC
TATTATCGAAGATATCAACGGGATCGAAACCATAAAATCACTAACCAGTGAAGAAAACCGTTACCAAAAAATTGACAGCG
ACTTTGTGGATTACCTCGATAAGTCCTTTAGGCTTAGTAAATATACCATCTTACAAGCCACACTTAAGCAAGGAGCGCAG
CTAATTCTGAATATCATCATTCTTTGGTTTGGGGCTCAACTGGTTATTAATGGTAGGATTTCAATTGGGCAGTTAATTAC
CTTTAACACACTTCTTGCCTATTTTACAACCCCTTTAGAAAATATCATTAATCTTCAAACCAAGCTCCAAGCAGCTAAGG
TTGCCAACAATCGTCTCAATGAGGTCTATCTTGTAGAGTCCGAATTTAAAGCCTCGCAAGCCTTATACGATTTATCGCTC
TTACAGGGTGACATTCAGTTTGAAGCTGTTTCCTATAGGTATGGCTTTGGCAAGGATACATTATCAGATATTACATTAAC
CATTAAGCAGGGAGCAAAAGTAACCCTTGTTGGTGTCAGCGGCTCAGGAAAAACAACCCTAGCCAAGATGCTCGTCAATT
TCTTTGAACCTTATAAGGGACGTATAACCATCAACCAAAACGATCTCAAGACCATTGATAAAAAGAATCTTCGACAATAC
ATCAACTACCTTCCACAACAAGCCTATATCTTTAATGGATCTATCTTAGAAAATCTAACCTTGGGAGCCAAGCAAGGCAT
CAGCCAGGAAGACATTCTTAACGCCTGTGAGATTGCTGACATTCGTCACGACATCGAGCAAATGCCAATGGGATACCAAA
CCGAGCTCTCTGATGGGGCTGGCTTATCTGGCGGACAAAAACAGAGAATTGCACTTGCTAGAGCATTACTAACCCAAGCT
CCTATACTAGTTCTTGATGAAGCAACCAGCGGACTTGACATACTGACAGAAAAGAAAATCATTGACCGTCTCATGAACAT
GACAGACAAAACGATTATTTTCGTTGCCCACCGGCTTAGTATCGCAGAGCGCACTGATCAGGTTGTGGTTCTTAATCAAG
GGCAAATCATTGAAACAGGCAGCCACCAGGAATTAATGAAACAAGGTGGATTTTATTACCACCTATTTAGTGAATAA

Domains

Predicted by InterproScan.

ABC transporter (ABC_tran)

(501-650)

Peptidase C39 family (Peptidase_C39)

(8-143)

ABC transporter transmembrane region (ABC_membrane)

(169-439)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

70.572

99.861

0.705
  comA Streptococcus mitis SK321

67.461

99.304

0.67
  comA Streptococcus mitis NCTC 12261

67.321

99.304

0.669
  comA Streptococcus pneumoniae D39

66.76

99.304

0.663
  comA Streptococcus pneumoniae Rx1

66.76

99.304

0.663
  comA Streptococcus pneumoniae R6

66.76

99.304

0.663
  comA Streptococcus pneumoniae TIGR4

66.48

99.304

0.66
  comA Streptococcus gordonii str. Challis substr. CH1

65.217

99.304

0.648