Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   KVP03_RS09575 Genome accession   NZ_CP077959
Coordinates   2021866..2022615 (-) Length   249 a.a.
NCBI ID   WP_042671079.1    Uniprot ID   -
Organism   Streptococcus equi subsp. zooepidemicus strain SEZ_14-145     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 2016866..2027615
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KVP03_RS09560 (KVP03_09540) - 2018821..2020179 (+) 1359 WP_230923090.1 bacteriocin secretion accessory protein -
  KVP03_RS09565 (KVP03_09545) - 2020279..2020413 (+) 135 WP_012516117.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  KVP03_RS10610 (KVP03_09550) - 2020532..2021866 (-) 1335 WP_111692697.1 sensor histidine kinase -
  KVP03_RS09575 (KVP03_09555) comE/blpR 2021866..2022615 (-) 750 WP_042671079.1 LytR/AlgR family response regulator transcription factor Regulator
  KVP03_RS09580 (KVP03_09560) - 2023242..2023445 (-) 204 WP_012516120.1 TmhB bacteriocin enhancer peptide -
  KVP03_RS09585 (KVP03_09565) - 2023462..2023719 (-) 258 WP_111678353.1 Blp family class II bacteriocin -
  KVP03_RS09590 (KVP03_09570) rlmD 2024040..2025407 (-) 1368 WP_230923091.1 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD -
  KVP03_RS09595 (KVP03_09575) - 2025404..2026372 (-) 969 WP_043030070.1 DNA-binding protein -
  KVP03_RS09600 (KVP03_09580) recX 2026436..2027212 (+) 777 WP_230923092.1 recombination regulator RecX -

Sequence

Protein


Download         Length: 249 a.a.        Molecular weight: 29227.69 Da        Isoelectric Point: 8.4602

>NTDB_id=585675 KVP03_RS09575 WP_042671079.1 2021866..2022615(-) (comE/blpR) [Streptococcus equi subsp. zooepidemicus strain SEZ_14-145]
MRVVILEDDMIQQRYLEKLIKELEVKHQLLFQGLDCFGRPHQLLSAIKKNCGQQLFFLDIEIKNEDKKGLEVARQIRQIN
PDAMIVFVTTHSEFMPLAFQYQVSALDYIDKELPHTEFVQRVETALLYAVRQNSETIAESAFYFTSRYAQVQVPFNDILY
IETSSRAHRVNLYTKKERMQFTGTLTDILKQESRFLQCHRSFLINPRNVVRVDKIERVVYFRNGSSCLIARSKMNSVLTT
IENLHRGDN

Nucleotide


Download         Length: 750 bp        

>NTDB_id=585675 KVP03_RS09575 WP_042671079.1 2021866..2022615(-) (comE/blpR) [Streptococcus equi subsp. zooepidemicus strain SEZ_14-145]
GTGAGAGTAGTTATTTTAGAAGATGATATGATTCAGCAGAGATATTTAGAAAAGCTCATTAAAGAGCTTGAGGTTAAGCA
CCAGCTATTATTTCAAGGACTTGACTGTTTTGGAAGGCCTCATCAGCTATTAAGTGCTATCAAGAAGAACTGTGGTCAGC
AGCTATTCTTTTTAGATATTGAGATAAAAAATGAGGACAAAAAAGGGCTTGAGGTTGCTAGGCAAATTCGTCAGATAAAT
CCAGATGCGATGATTGTTTTTGTAACGACTCACTCGGAATTTATGCCCTTGGCTTTTCAGTATCAGGTATCTGCTTTGGA
CTATATCGATAAAGAGCTGCCTCACACTGAGTTTGTTCAACGGGTAGAGACTGCTTTATTATATGCTGTGCGGCAAAATA
GTGAAACGATAGCGGAAAGTGCTTTTTATTTTACATCTCGTTATGCTCAGGTACAGGTGCCTTTTAATGATATCCTGTAT
ATTGAGACATCGTCACGAGCGCATCGTGTCAATTTGTATACAAAAAAGGAGAGAATGCAATTTACAGGGACTTTGACGGA
TATTTTGAAGCAAGAGTCTCGTTTTTTGCAATGTCATCGTTCTTTTTTGATTAATCCTAGGAATGTCGTTAGAGTAGATA
AGATTGAGCGAGTGGTTTATTTTCGAAATGGCTCTAGCTGCTTAATTGCTCGTAGTAAAATGAACAGTGTTTTAACAACA
ATTGAGAACCTACATAGAGGAGATAATTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-122)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

52.61

100

0.526
  comE/comE1 Streptococcus equinus JB1

40.167

95.984

0.386