Detailed information    

insolico Bioinformatically predicted

Overview

Name   comC   Type   Regulator
Locus tag   I872_RS10625 Genome accession   NC_021175
Coordinates   2138686..2138814 (-) Length   42 a.a.
NCBI ID   WP_041826850.1    Uniprot ID   Q197M7
Organism   Streptococcus cristatus AS 1.3089     
Function   binding to ComD; induce autophosphorylation of ComD (predicted from homology)   
Competence regulation

Genomic Context

Location: 2133686..2143814
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I872_RS10590 (I872_10645) - 2133967..2134623 (+) 657 WP_015606085.1 LysM peptidoglycan-binding domain-containing protein -
  I872_RS10595 (I872_10650) sdaAA 2134681..2135553 (-) 873 WP_015606086.1 L-serine ammonia-lyase, iron-sulfur-dependent, subunit alpha -
  I872_RS10600 (I872_10655) sdaAB 2135562..2136233 (-) 672 WP_015606087.1 L-serine ammonia-lyase, iron-sulfur-dependent subunit beta -
  I872_RS10615 (I872_10660) comE/comE2 2136577..2137320 (-) 744 WP_005591384.1 competence system response regulator transcription factor ComE Regulator
  I872_RS10620 (I872_10665) comD/comD1 2137317..2138660 (-) 1344 WP_172456456.1 GHKL domain-containing protein Regulator
  I872_RS10625 comC 2138686..2138814 (-) 129 WP_041826850.1 competence protein Regulator
  I872_RS10635 (I872_10670) rlmH 2139108..2139587 (-) 480 WP_015606089.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  I872_RS10640 (I872_10675) htrA 2139790..2140968 (+) 1179 WP_015606090.1 S1C family serine protease Regulator
  I872_RS10645 (I872_10680) spo0J 2141031..2141792 (+) 762 WP_015606091.1 ParB/RepB/Spo0J family partition protein Regulator

Sequence

Protein


Download         Length: 42 a.a.        Molecular weight: 5021.99 Da        Isoelectric Point: 10.8240

>NTDB_id=58492 I872_RS10625 WP_041826850.1 2138686..2138814(-) (comC) [Streptococcus cristatus AS 1.3089]
MKNTQKNFKTIAYFPVLNEKELKEVFGGDSRNIFLKIKFKKK

Nucleotide


Download         Length: 129 bp        

>NTDB_id=58492 I872_RS10625 WP_041826850.1 2138686..2138814(-) (comC) [Streptococcus cristatus AS 1.3089]
ATGAAAAATACTCAGAAAAACTTTAAAACAATCGCTTACTTCCCAGTCTTGAATGAAAAAGAACTTAAAGAAGTTTTTGG
AGGAGATTCAAGAAATATCTTCTTAAAAATTAAATTTAAGAAAAAATAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q197M7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comC Streptococcus sinensis strain Forsyth1A

63.636

78.571

0.5
  comC Streptococcus mitis SK321

46.154

92.857

0.429

Multiple sequence alignment