Detailed information NTG0058491

Bioinformatically predicted

Overview

• Name: comD/comD1
• Type: Regulator
• Locus tag: I872_RS10620
• Genome accession: NC_021175
• Coordinates: 2137317..2138660 (-)
• Length: 447 a.a.
• NCBI ID: WP_172456456.1
• Uniprot ID: -
• Organism: Streptococcus cristatus AS 1.3089
• Function: phosphorylation of ComE (predicted from homology) Competence regulation

Genomic Context

Location: 2132317..2143660

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I872_RS10585 (I872_10640)	-	2132987..2133781 (+)	795	WP_015606084.1	energy-coupling factor transporter transmembrane component T family protein	-
I872_RS10590 (I872_10645)	-	2133967..2134623 (+)	657	WP_015606085.1	LysM peptidoglycan-binding domain-containing protein	-
I872_RS10595 (I872_10650)	sdaAA	2134681..2135553 (-)	873	WP_015606086.1	L-serine ammonia-lyase, iron-sulfur-dependent, subunit alpha	-
I872_RS10600 (I872_10655)	sdaAB	2135562..2136233 (-)	672	WP_015606087.1	L-serine ammonia-lyase, iron-sulfur-dependent subunit beta	-
I872_RS10615 (I872_10660)	comE/comE2	2136577..2137320 (-)	744	WP_005591384.1	competence system response regulator transcription factor ComE	Regulator
I872_RS10620 (I872_10665)	comD/comD1	2137317..2138660 (-)	1344	WP_172456456.1	GHKL domain-containing protein	Regulator
I872_RS10625	comC	2138686..2138814 (-)	129	WP_041826850.1	competence protein	Regulator
I872_RS10635 (I872_10670)	rlmH	2139108..2139587 (-)	480	WP_015606089.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
I872_RS10640 (I872_10675)	htrA	2139790..2140968 (+)	1179	WP_015606090.1	S1C family serine protease	Regulator
I872_RS10645 (I872_10680)	spo0J	2141031..2141792 (+)	762	WP_015606091.1	ParB/RepB/Spo0J family partition protein	Regulator

Sequence

Protein

• Length: 447 a.a.
• Molecular weight: 53083.12 Da
• Isoelectric Point: 5.5650

>NTDB_id=58491 I872_RS10620 WP_172456456.1 2137317..2138660(-) (comD/comD1) [Streptococcus cristatus AS 1.3089]
MFELFFWILQAAIEVYFTIVIYEKINKVKSSFYFTFLCAIVLILLPLLILNLESIFSLSRHVLYFLLLLIYPLFFYRYFY
KKEKLSALFSIFLSLLLYLTVQAPTTFFSVIISSITGDSFVNDNWAVFYIMINSISVLLMLKFIDYLPFSIRDFKEEVFK
KTIKRINIFYVIDIFILNISHWLSEDEHFNSFSSMLATICFLIFMTTLFYLKAIREKYEKEEEIRQRELEQLQLQQYTDE
IVSLYNEIRGFRHDYAGMLTSFQTAINTQDIKEIEKIYQEVLVDANLKLRSDKYTYFDLNNVGDSALRSVMTETLFKARE
HQIDLTFEVKEPVETLPIKLLDVVRMASILLNNAVEGAIESYEKMIHVTLVQLDTEIIFVVKNSRKQRKLDLEEIYKPEF
STKGYRRGLGLNNLKEILENYEYIMLDTEISKYDFTQVLTIKRRNSL

Nucleotide

• Length: 1344 bp

>NTDB_id=58491 I872_RS10620 WP_172456456.1 2137317..2138660(-) (comD/comD1) [Streptococcus cristatus AS 1.3089]
ATGTTTGAATTATTTTTTTGGATATTACAAGCTGCCATTGAAGTATATTTCACTATTGTCATATATGAAAAGATCAATAA
AGTAAAATCGAGTTTTTACTTTACTTTTCTGTGTGCTATAGTCTTAATTTTATTACCCTTACTCATATTAAATTTAGAAT
CTATATTTTCTTTGTCAAGGCATGTTCTATATTTTCTTTTACTACTGATTTATCCTCTTTTTTTCTACAGGTATTTTTAT
AAAAAAGAAAAGTTATCAGCTCTTTTCTCTATATTTCTATCTCTTCTTCTTTATTTAACAGTTCAGGCTCCTACTACATT
TTTTTCCGTCATTATTTCCTCAATTACAGGGGATTCATTTGTAAACGATAATTGGGCTGTCTTTTATATCATGATAAATA
GTATCTCTGTTTTATTAATGCTTAAGTTTATTGATTACTTACCATTTTCTATAAGAGATTTTAAAGAGGAGGTCTTTAAA
AAGACAATTAAGAGAATTAATATTTTTTATGTTATAGATATTTTCATTTTAAATATTTCTCATTGGTTGAGTGAAGATGA
GCATTTTAATAGTTTTAGCAGTATGCTAGCGACTATTTGTTTCTTGATCTTTATGACGACTCTTTTCTATTTGAAAGCGA
TTCGGGAAAAGTATGAAAAAGAAGAGGAGATTCGACAAAGAGAATTGGAACAGTTGCAGCTGCAGCAGTACACAGATGAA
ATTGTTTCTCTTTATAATGAAATTCGTGGCTTTCGTCATGATTATGCTGGCATGCTGACTAGCTTTCAGACAGCCATCAA
TACGCAAGATATCAAGGAAATTGAAAAAATATATCAAGAAGTTTTAGTCGATGCGAATTTGAAATTACGTTCAGACAAAT
ACACCTATTTTGATTTGAATAATGTTGGTGACTCAGCTCTTCGAAGCGTTATGACAGAGACTTTGTTCAAGGCGCGTGAA
CACCAGATTGATTTGACATTTGAGGTTAAAGAGCCTGTTGAGACATTACCAATTAAGCTATTAGATGTGGTAAGAATGGC
CAGTATTTTGCTAAACAATGCTGTTGAAGGCGCAATTGAAAGCTATGAAAAAATGATTCATGTGACTTTAGTTCAACTCG
ATACAGAAATCATTTTTGTTGTAAAAAATTCCCGCAAGCAAAGAAAATTAGATTTAGAAGAAATTTATAAACCAGAGTTC
TCAACCAAAGGTTATCGAAGAGGCCTAGGTTTAAATAATCTAAAAGAAATTTTAGAGAATTATGAATATATCATGCTGGA
TACAGAAATAAGTAAGTATGATTTCACCCAAGTATTAACAATTAAAAGAAGGAATAGTTTATGA

Domains

Predicted by InterproScan.

• GHKL domain (HATPase_c_5) (339-441)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comD/comD1	Streptococcus gordonii str. Challis substr. CH1	55.27	87.025	0.481
comD/comD2	Streptococcus gordonii strain NCTC7865	54.145	86.353	0.468
comD/comD1	Streptococcus pneumoniae Rx1	42.579	91.946	0.391
comD/comD1	Streptococcus pneumoniae D39	42.579	91.946	0.391
comD/comD1	Streptococcus pneumoniae R6	42.579	91.946	0.391
comD	Streptococcus mitis NCTC 12261	43.073	88.814	0.383
comD/comD2	Streptococcus pneumoniae TIGR4	44	83.893	0.369
comD	Streptococcus mitis SK321	42.933	83.893	0.36