Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   VB13_RS08610 Genome accession   NZ_CP077685
Coordinates   1760445..1761668 (+) Length   407 a.a.
NCBI ID   WP_009880337.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain M49 591     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1755445..1766668
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VB13_RS08595 (VB13_08855) - 1758379..1759359 (-) 981 WP_009880338.1 IS30 family transposase -
  VB13_RS08605 (VB13_08865) rlmH 1759754..1760233 (-) 480 WP_002981964.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  VB13_RS08610 (VB13_08870) htrA 1760445..1761668 (+) 1224 WP_009880337.1 S1C family serine protease Regulator
  VB13_RS08615 (VB13_08875) spo0J 1761757..1762533 (+) 777 WP_044555304.1 ParB/RepB/Spo0J family partition protein Regulator

Sequence

Protein


Download         Length: 407 a.a.        Molecular weight: 42774.40 Da        Isoelectric Point: 7.3920

>NTDB_id=582260 VB13_RS08610 WP_009880337.1 1760445..1761668(+) (htrA) [Streptococcus pyogenes strain M49 591]
MPSMKHILKSLSILLIGFLGGLIAIITFNNLYPHSPSKINSGKATTSNMVFNNTTNTTKAVKAVQNAVVSVINYQDNPSS
TLSNPYTKLFGEGRSKENKDAELSIFSEGSGVIYRKDGNSAYVVTNNHVIDGAKRIEILMADGSKVVGELVGADTYSDLA
VVKISSDKIKTVAEFADSTKLNVGEVAIAIGSPLGTQYANSVTQGIVSSLSRTVTLKNENGETVSTNAIQTDAAINPGNS
GGPLINIEGQVIGINSSKISSTPTGSNGNSGAVEGIGFAIPSTDVIKIIKQLETNGEVIRPALGISMVNLNDLSTNALSQ
INIPTSVTGGIVVAEVKEGMPASGKLAQYDVITEIDGKTVNSISDLQSSLYGHDINDTIKVTFYRGTTKKKADIKLTKTT
QDLTKTQ

Nucleotide


Download         Length: 1224 bp        

>NTDB_id=582260 VB13_RS08610 WP_009880337.1 1760445..1761668(+) (htrA) [Streptococcus pyogenes strain M49 591]
ATGCCAAGTATGAAACATATCTTAAAATCTTTAAGTATTTTACTAATTGGATTTTTAGGAGGATTAATAGCAATTATTAC
ATTCAATAATCTCTACCCACATTCTCCTTCAAAAATAAATTCAGGTAAGGCAACAACTAGTAATATGGTTTTTAACAACA
CAACCAATACTACTAAAGCTGTCAAAGCTGTTCAAAATGCAGTTGTATCAGTTATTAATTATCAAGATAACCCTTCTTCA
ACCCTTTCTAACCCTTATACAAAACTCTTTGGAGAAGGGCGTTCAAAAGAGAATAAGGATGCTGAATTATCTATTTTTAG
TGAAGGATCTGGGGTCATTTATCGAAAAGATGGCAACTCCGCTTACGTTGTTACTAATAACCATGTTATCGACGGAGCTA
AACGGATTGAAATTCTTATGGCAGACGGATCTAAAGTTGTTGGTGAATTAGTTGGAGCTGATACTTATTCGGATTTAGCT
GTTGTTAAGATCTCTTCAGATAAGATAAAAACAGTAGCTGAATTTGCAGACTCTACAAAACTAAATGTTGGAGAAGTTGC
TATTGCTATCGGCAGCCCACTAGGAACACAATACGCTAATTCTGTTACTCAAGGAATCGTCTCTAGTTTAAGTCGTACTG
TAACTTTAAAAAACGAGAATGGTGAGACTGTCTCAACAAATGCTATTCAGACAGATGCTGCTATTAACCCTGGAAACTCT
GGTGGACCACTAATTAATATTGAGGGGCAAGTAATCGGAATTAATTCAAGTAAAATTTCTTCTACCCCAACTGGTAGCAA
CGGTAATAGTGGTGCTGTTGAAGGAATTGGTTTTGCTATCCCATCTACTGACGTTATTAAAATTATTAAACAACTAGAAA
CTAATGGTGAAGTTATCAGACCTGCTCTTGGAATATCCATGGTCAATTTAAATGACTTATCCACAAATGCTCTTAGCCAA
ATTAATATTCCAACTAGTGTAACTGGTGGTATTGTAGTAGCAGAAGTTAAGGAAGGAATGCCGGCATCTGGCAAACTTGC
TCAGTACGATGTGATTACAGAAATTGATGGCAAAACAGTTAATTCAATTAGTGATTTACAAAGTAGTCTATACGGACACG
ATATTAATGATACTATTAAAGTAACTTTTTATAGAGGAACTACAAAGAAAAAAGCAGATATCAAATTAACAAAAACTACT
CAAGATTTGACTAAAACGCAGTAA

Domains

Predicted by InterproScan.

PDZ domain (PDZ_2)

(301-396)

Trypsin-like peptidase domain (Trypsin_2)

(109-254)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

61.881

99.263

0.614
  htrA Streptococcus gordonii str. Challis substr. CH1

55.224

98.771

0.545
  htrA Streptococcus mitis NCTC 12261

52.826

100

0.528
  htrA Streptococcus pneumoniae Rx1

52.58

100

0.526
  htrA Streptococcus pneumoniae D39

52.58

100

0.526
  htrA Streptococcus pneumoniae R6

52.58

100

0.526
  htrA Streptococcus pneumoniae TIGR4

52.58

100

0.526