Detailed information NTG0581804

Bioinformatically predicted

Overview

• Name: comGF
• Type: Machinery gene
• Locus tag: MP619_RS01090
• Genome accession: NZ_CP095081
• Coordinates: 172643..173083 (+)
• Length: 146 a.a.
• NCBI ID: WP_129555187.1
• Uniprot ID: -
• Organism: Streptococcus dysgalactiae strain WJ001
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 167643..178083

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MP619_RS01050 (MP619_01045)	-	169039..169467 (+)	429	WP_268227804.1	DUF1366 domain-containing protein	-
MP619_RS01055 (MP619_01050)	-	169433..169660 (+)	228	WP_037588167.1	hypothetical protein	-
MP619_RS01060 (MP619_01055)	-	169668..170135 (+)	468	WP_155783054.1	phage holin family protein	-
MP619_RS01065 (MP619_01060)	-	170128..170460 (+)	333	WP_155782998.1	phage holin	-
MP619_RS01070 (MP619_01065)	-	170438..171667 (+)	1230	WP_155782997.1	N-acetylmuramoyl-L-alanine amidase	-
MP619_RS01075 (MP619_01070)	prx	171811..172002 (+)	192	WP_155778416.1	hypothetical protein	Regulator
MP619_RS01080 (MP619_01075)	comGD	172017..172409 (+)	393	WP_343237803.1	competence type IV pilus minor pilin ComGD	Machinery gene
MP619_RS01085 (MP619_01080)	comGE	172366..172662 (+)	297	WP_129555186.1	competence type IV pilus minor pilin ComGE	Machinery gene
MP619_RS01090 (MP619_01085)	comGF	172643..173083 (+)	441	WP_129555187.1	competence type IV pilus minor pilin ComGF	Machinery gene
MP619_RS01095 (MP619_01090)	comGG	173106..173435 (+)	330	WP_231112812.1	competence type IV pilus minor pilin ComGG	-
MP619_RS01100 (MP619_01095)	comGH	173498..174451 (+)	954	WP_129555189.1	class I SAM-dependent methyltransferase	Machinery gene
MP619_RS01105 (MP619_01100)	-	174510..175706 (+)	1197	WP_129555190.1	acetate kinase	-
MP619_RS01110 (MP619_01105)	-	176012..176219 (+)	208	Protein_171	helix-turn-helix transcriptional regulator	-
MP619_RS01115 (MP619_01110)	-	176322..177002 (+)	681	WP_268227805.1	type II CAAX endopeptidase family protein	-
MP619_RS01120 (MP619_01115)	-	177020..177457 (+)	438	WP_129555192.1	hypothetical protein	-

Sequence

Protein

• Length: 146 a.a.
• Molecular weight: 17012.54 Da
• Isoelectric Point: 10.5665

>NTDB_id=581804 MP619_RS01090 WP_129555187.1 172643..173083(+) (comGF) [Streptococcus dysgalactiae strain WJ001]
MKKRTGRVQAFTFLEALIALLVISGSLLVYQGLTKTLFSHSRYLTNHDQDHWLLFSQQLREELSGARFHKVENNKLYIEK
GKKKLVLGQFKSHDFRKSAGNGQGYQPMLFGLSHSHIQAEQSRIRITLHWKSGLERTFYYAFQDQP

Nucleotide

• Length: 441 bp

>NTDB_id=581804 MP619_RS01090 WP_129555187.1 172643..173083(+) (comGF) [Streptococcus dysgalactiae strain WJ001]
TTGAAAAAAAGGACAGGTAGGGTCCAAGCATTTACTTTTTTAGAGGCTTTAATTGCCTTGCTGGTGATATCAGGTTCTCT
TCTAGTGTATCAAGGATTGACCAAAACACTCTTTAGCCACAGTCGCTACCTTACCAACCACGATCAAGACCATTGGCTTT
TGTTCTCCCAGCAGTTACGAGAAGAGTTAAGTGGAGCGCGATTTCACAAAGTAGAGAACAATAAATTATATATCGAAAAA
GGCAAGAAAAAACTAGTTTTAGGACAATTTAAAAGCCATGACTTTCGAAAATCGGCAGGCAATGGACAAGGTTATCAACC
CATGCTGTTTGGCTTGTCTCATAGTCATATACAAGCAGAGCAGTCTCGTATTCGGATTACCCTTCACTGGAAAAGTGGAC
TAGAAAGGACCTTCTACTATGCATTTCAAGACCAACCTTAA

Domains

Predicted by InterProScan.

• Putative Competence protein ComGF (ComGF) (40-135)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF	Streptococcus mutans UA159	47.482	95.205	0.452
comGF	Streptococcus mutans UA140	46.763	95.205	0.445
comGF	Lactococcus lactis subsp. cremoris KW2	47.101	94.521	0.445
comGF/cglF	Streptococcus mitis SK321	43.796	93.836	0.411
comGF/cglF	Streptococcus pneumoniae R6	43.796	93.836	0.411
comGF/cglF	Streptococcus pneumoniae TIGR4	43.796	93.836	0.411
comGF/cglF	Streptococcus pneumoniae D39	43.796	93.836	0.411
comGF/cglF	Streptococcus mitis NCTC 12261	43.796	93.836	0.411
comGF/cglF	Streptococcus pneumoniae Rx1	43.796	93.836	0.411