Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGH   Type   Machinery gene
Locus tag   MP619_RS01100 Genome accession   NZ_CP095081
Coordinates   173498..174451 (+) Length   317 a.a.
NCBI ID   WP_129555189.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae strain WJ001     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 168498..179451
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MP619_RS01050 (MP619_01045) - 169039..169467 (+) 429 WP_268227804.1 DUF1366 domain-containing protein -
  MP619_RS01055 (MP619_01050) - 169433..169660 (+) 228 WP_037588167.1 hypothetical protein -
  MP619_RS01060 (MP619_01055) - 169668..170135 (+) 468 WP_155783054.1 phage holin family protein -
  MP619_RS01065 (MP619_01060) - 170128..170460 (+) 333 WP_155782998.1 phage holin -
  MP619_RS01070 (MP619_01065) - 170438..171667 (+) 1230 WP_155782997.1 N-acetylmuramoyl-L-alanine amidase -
  MP619_RS01075 (MP619_01070) prx 171811..172002 (+) 192 WP_155778416.1 hypothetical protein Regulator
  MP619_RS01080 (MP619_01075) comGD 172017..172409 (+) 393 WP_343237803.1 competence type IV pilus minor pilin ComGD Machinery gene
  MP619_RS01085 (MP619_01080) comGE 172366..172662 (+) 297 WP_129555186.1 competence type IV pilus minor pilin ComGE Machinery gene
  MP619_RS01090 (MP619_01085) comGF 172643..173083 (+) 441 WP_129555187.1 competence type IV pilus minor pilin ComGF Machinery gene
  MP619_RS01095 (MP619_01090) comGG 173106..173435 (+) 330 WP_231112812.1 competence type IV pilus minor pilin ComGG -
  MP619_RS01100 (MP619_01095) comGH 173498..174451 (+) 954 WP_129555189.1 class I SAM-dependent methyltransferase Machinery gene
  MP619_RS01105 (MP619_01100) - 174510..175706 (+) 1197 WP_129555190.1 acetate kinase -
  MP619_RS01110 (MP619_01105) - 176012..176219 (+) 208 Protein_171 helix-turn-helix transcriptional regulator -
  MP619_RS01115 (MP619_01110) - 176322..177002 (+) 681 WP_268227805.1 type II CAAX endopeptidase family protein -
  MP619_RS01120 (MP619_01115) - 177020..177457 (+) 438 WP_129555192.1 hypothetical protein -
  MP619_RS01125 (MP619_01120) proC 177550..178326 (-) 777 WP_129555193.1 pyrroline-5-carboxylate reductase -
  MP619_RS01130 (MP619_01125) pepA 178373..179440 (-) 1068 WP_129555194.1 glutamyl aminopeptidase -

Sequence

Protein


Download         Length: 317 a.a.        Molecular weight: 36090.98 Da        Isoelectric Point: 4.7292

>NTDB_id=581805 MP619_RS01100 WP_129555189.1 173498..174451(+) (comGH) [Streptococcus dysgalactiae strain WJ001]
MNFEKIEEAYQLLLENSQLIENDLKTHIYDAIVEQNSFYLGAEGASPQVAQNINKLKALHLTKEEWRRAYQFIFIKAAQT
EQLQANHQFTPDAIGFILLYLLEQLSDKDSLEILEIGSGTGNLAQTLLNNTSKKLDYVGIELDDLLIDLSASIAEVMDSS
ARFIQEDAVRPQLLKESDVVISDLPVGYYPNDDIAKRYKVASSEEHTYAHHLLMEQSLKYLKKDGFAIFLEPVNLLTSSQ
SQLLKNWLTGYAQVVALITLPDSIFGHPSNAKSIIVLQKQTDHPTETFVYPIRDLKLAENIHDFMQNFKKWKQDNVN

Nucleotide


Download         Length: 954 bp        

>NTDB_id=581805 MP619_RS01100 WP_129555189.1 173498..174451(+) (comGH) [Streptococcus dysgalactiae strain WJ001]
ATGAATTTTGAAAAAATTGAAGAAGCCTATCAGTTACTTTTAGAGAATAGTCAACTGATTGAAAATGATCTAAAAACACA
TATTTATGATGCCATCGTTGAGCAAAACTCTTTTTATTTAGGTGCTGAGGGAGCTAGTCCTCAAGTTGCCCAGAACATTA
ACAAACTGAAAGCCTTACACCTGACTAAAGAAGAATGGCGTAGAGCTTACCAGTTTATTTTTATTAAGGCAGCTCAGACT
GAGCAGCTCCAAGCAAACCATCAGTTCACGCCAGATGCTATTGGTTTTATTCTGCTGTATCTTTTGGAACAATTGAGTGA
CAAAGATAGCCTAGAAATCCTTGAAATTGGCAGTGGTACGGGAAATCTAGCACAAACTCTCCTCAATAATACGAGTAAGA
AACTTGATTATGTAGGGATTGAACTTGACGACCTCTTAATTGATTTATCAGCAAGTATTGCTGAAGTAATGGACTCTTCA
GCTCGTTTTATTCAAGAAGATGCGGTAAGACCGCAATTGTTAAAAGAAAGCGATGTTGTTATCAGTGACTTGCCAGTGGG
TTATTATCCTAATGATGACATTGCTAAGCGCTATAAGGTAGCTAGTTCTGAGGAACACACCTATGCTCATCATTTACTCA
TGGAACAATCTTTAAAGTATTTGAAAAAAGATGGCTTTGCCATTTTCTTGGAACCTGTGAATTTGTTGACAAGCTCTCAG
AGCCAATTGTTGAAAAATTGGCTAACTGGCTATGCCCAGGTAGTGGCCTTGATTACTCTACCAGATTCTATATTTGGTCA
TCCTTCTAATGCTAAGTCCATTATTGTCTTGCAAAAGCAGACAGACCATCCGACGGAAACCTTTGTTTATCCTATTCGAG
ACTTGAAACTTGCAGAGAATATTCATGACTTTATGCAAAATTTCAAAAAATGGAAACAGGATAATGTCAATTAA

Domains

Predicted by InterProScan.

N-6 DNA Methylase (N6_Mtase)

(68-290)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGH Streptococcus mutans UA140

66.456

99.685

0.662
  comGH Streptococcus mutans UA159

66.139

99.685

0.659