Detailed information NTG0581475

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: JGX27_RS00355
• Genome accession: NZ_CP077423
• Coordinates: 53665..54564 (+)
• Length: 299 a.a.
• NCBI ID: WP_009853198.1
• Uniprot ID: -
• Organism: Streptococcus gallolyticus subsp. gallolyticus TX20005
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 48665..59564

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JGX27_RS00330 (JGX27_00330)	-	48864..49313 (+)	450	WP_009853193.1	DUF523 domain-containing protein	-
JGX27_RS00335 (JGX27_00335)	purE	49313..49801 (+)	489	WP_009853194.1	5-(carboxyamino)imidazole ribonucleotide mutase	-
JGX27_RS00340 (JGX27_00340)	purK	49788..50861 (+)	1074	WP_009853195.1	5-(carboxyamino)imidazole ribonucleotide synthase	-
JGX27_RS00345 (JGX27_00345)	-	50872..51918 (+)	1047	WP_014619874.1	hypothetical protein	-
JGX27_RS00350 (JGX27_00350)	purB	52220..53518 (+)	1299	WP_009853197.1	adenylosuccinate lyase	-
JGX27_RS00355 (JGX27_00355)	comR	53665..54564 (+)	900	WP_009853198.1	XRE family transcriptional regulator	Regulator
JGX27_RS00360 (JGX27_00360)	-	55806..56237 (+)	432	WP_009853200.1	low molecular weight protein-tyrosine-phosphatase	-
JGX27_RS00365 (JGX27_00365)	-	56257..56637 (+)	381	WP_009853201.1	membrane protein	-
JGX27_RS00370 (JGX27_00370)	-	56634..58427 (+)	1794	WP_009853202.1	acyltransferase family protein	-

Sequence

Protein

• Length: 299 a.a.
• Molecular weight: 34967.15 Da
• Isoelectric Point: 5.1732

>NTDB_id=581475 JGX27_RS00355 WP_009853198.1 53665..54564(+) (comR) [Streptococcus gallolyticus subsp. gallolyticus TX20005]
MEKFGIKVRALREKKGISREEFCGDETELSVRQLARIEKGQSVPTLNKVGYIAKVLGVTIGELTDGKNLELPTRYKELKY
LLLRTPTYGDKERLKRQTSYFDEISEKYYEVIPEEERLIIDCLQSKIDVHFSDDVNFGEGILNDYFDQVRRKKNFQINDL
ILIDLYFACLASAKSFVGIYSLDLYDELMECLLNQENLSPETSLILNNVLLNNVDLVLRFHRESFMKRIIIKSDTIMTSV
HDFQRRPVLSLVEWKYYLQFKKDFLAAQKSYSNAILFANLIGDTYLENKLIEEWNNDTT

Nucleotide

• Length: 900 bp

>NTDB_id=581475 JGX27_RS00355 WP_009853198.1 53665..54564(+) (comR) [Streptococcus gallolyticus subsp. gallolyticus TX20005]
TTGGAAAAGTTTGGGATTAAAGTACGTGCATTAAGAGAGAAAAAAGGGATTTCACGTGAAGAATTCTGTGGTGATGAAAC
AGAATTATCTGTGAGACAGCTAGCTAGAATTGAAAAAGGACAATCCGTCCCAACTCTTAATAAGGTGGGATATATTGCAA
AAGTATTAGGAGTAACTATTGGTGAGTTAACTGATGGTAAAAATTTAGAACTTCCCACTCGGTATAAGGAGTTAAAATAT
TTACTATTACGAACACCAACTTATGGGGATAAGGAACGTCTTAAGAGACAAACTTCATATTTTGATGAAATTTCAGAAAA
ATACTATGAAGTTATACCTGAAGAAGAACGCTTAATTATTGATTGTTTACAATCGAAGATTGATGTTCATTTTAGTGATG
ATGTTAATTTTGGTGAAGGAATTTTAAATGATTATTTTGACCAAGTTAGACGAAAGAAGAACTTTCAAATTAATGATTTG
ATTTTAATAGATTTATATTTTGCTTGCCTTGCTTCTGCTAAATCGTTTGTGGGAATCTATAGCTTAGATTTGTATGATGA
ATTAATGGAGTGTTTACTAAATCAAGAAAATCTTTCACCAGAAACTTCTTTGATTTTAAATAATGTTTTGTTAAATAATG
TAGATTTGGTTTTACGATTCCATAGAGAATCTTTTATGAAACGAATTATTATAAAAAGTGACACTATCATGACAAGTGTT
CATGATTTTCAAAGACGTCCAGTTTTAAGTTTAGTTGAGTGGAAATATTATTTACAATTTAAAAAAGATTTTTTAGCGGC
ACAAAAATCTTACTCCAATGCTATTTTATTTGCTAACTTAATTGGAGATACTTATTTGGAAAATAAGTTAATAGAAGAAT
GGAATAATGACACAACATGA

Domains

Predicted by InterproScan.

• Helix-turn-helix (HTH_3) (8-63)

• ComR tetratricopeptide (ComR_TPR) (72-294)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus infantarius subsp. infantarius ATCC BAA-102	72.474	95.987	0.696
comR	Streptococcus mutans UA159	54.515	100	0.545
comR	Streptococcus pyogenes MGAS8232	49.333	100	0.495
comR	Streptococcus pyogenes MGAS315	47.315	99.666	0.472
comR	Streptococcus suis P1/7	39.799	100	0.398
comR	Streptococcus suis 05ZYH33	39.799	100	0.398
comR	Streptococcus suis D9	37.71	99.331	0.375