Detailed information NTG0581338

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: I6L88_RS09165
• Genome accession: NZ_CP077404
• Coordinates: 1847277..1848191 (+)
• Length: 304 a.a.
• NCBI ID: WP_002280105.1
• Uniprot ID: -
• Organism: Streptococcus mutans strain FDAARGOS 1458
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1842277..1853191

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6L88_RS09140 (I6L88_09140)	-	1842721..1843140 (+)	420	WP_002280110.1	SRPBCC family protein	-
I6L88_RS09145 (I6L88_09145)	-	1843244..1843840 (+)	597	WP_002280109.1	hypothetical protein	-
I6L88_RS09150 (I6L88_09150)	-	1843862..1844593 (+)	732	WP_002280108.1	hypothetical protein	-
I6L88_RS09155 (I6L88_09155)	purB	1844887..1846185 (+)	1299	WP_002280107.1	adenylosuccinate lyase	-
I6L88_RS09160 (I6L88_09160)	-	1846205..1846891 (+)	687	WP_002280106.1	DNA alkylation repair protein	-
I6L88_RS09165 (I6L88_09165)	comR	1847277..1848191 (+)	915	WP_002280105.1	helix-turn-helix domain-containing protein	Regulator
I6L88_RS09170 (I6L88_09170)	-	1848723..1850567 (-)	1845	WP_002280104.1	carbohydrate-binding domain-containing protein	-
I6L88_RS09175 (I6L88_09175)	-	1851065..1851340 (+)	276	WP_002270796.1	hypothetical protein	-
I6L88_RS09180 (I6L88_09180)	-	1851436..1853058 (+)	1623	WP_002280103.1	class I SAM-dependent DNA methyltransferase	-

Sequence

Protein

• Length: 304 a.a.
• Molecular weight: 35304.52 Da
• Isoelectric Point: 5.1281

>NTDB_id=581338 I6L88_RS09165 WP_002280105.1 1847277..1848191(+) (comR) [Streptococcus mutans strain FDAARGOS 1458]
MLKDFGKKIKSLRLEKGLTKEAVCLDESQLSTRQLTRIESGQSMPTLNKAIYIVGRLGVTLGYLTDGENVELPSRYKELK
YLLLRTPTYGDQQRLTEKETYFDEIFSQFYDDLPEEEQLIIDGLQSKLDIHFSDNIDFGVGILNDYFDQILRKTNYQVND
LILIDLYFSCLTVSGLDSAIFDSRKYNQLLETLLKQVDCLPLEDLFVLNNVLLNNFGLLLELKKYDFVKQLIAVSNKIMA
RTHDFQKKPIVNLLTWKHHLFVEKDYAKAKKSYDAAILFAQLTENINLRENLEKEWQKDSQNGT

Nucleotide

• Length: 915 bp

>NTDB_id=581338 I6L88_RS09165 WP_002280105.1 1847277..1848191(+) (comR) [Streptococcus mutans strain FDAARGOS 1458]
ATGTTAAAAGATTTTGGGAAGAAAATTAAGAGCCTGAGGTTAGAAAAGGGGCTGACCAAAGAGGCTGTCTGCCTTGATGA
ATCGCAGTTGTCAACACGGCAGCTGACTAGAATTGAATCAGGACAGTCTATGCCAACTCTTAATAAAGCTATTTATATTG
TAGGACGTTTAGGAGTAACGCTTGGCTATTTAACGGACGGAGAAAATGTCGAGTTACCCAGTCGTTATAAAGAACTAAAG
TATTTATTATTACGAACGCCAACCTATGGTGACCAACAAAGATTAACTGAAAAAGAAACCTATTTTGACGAGATTTTTAG
TCAGTTTTATGATGATTTGCCTGAAGAAGAACAATTGATTATTGATGGTTTACAATCGAAACTAGATATTCATTTTAGTG
ACAATATCGATTTTGGCGTTGGTATTTTAAATGACTATTTTGATCAGATTTTAAGAAAAACCAATTATCAGGTCAATGAT
TTGATTCTGATTGATCTCTATTTTTCCTGCTTAACTGTTAGTGGTTTGGATTCAGCTATTTTTGATTCAAGAAAATATAA
TCAATTATTGGAGACATTGCTTAAGCAGGTAGACTGCCTTCCATTGGAAGATCTTTTCGTTTTAAATAATGTTTTATTGA
ATAATTTTGGACTCCTTTTAGAATTGAAAAAATATGATTTTGTTAAGCAGCTTATTGCTGTTAGCAATAAAATCATGGCT
AGAACTCATGATTTTCAAAAAAAGCCTATTGTTAATCTTCTGACATGGAAGCATCATTTATTTGTTGAAAAAGATTATGC
GAAAGCTAAAAAGAGCTATGATGCTGCTATCTTATTTGCCCAGTTAACAGAAAACATTAATTTAAGAGAAAATTTGGAGA
AAGAATGGCAAAAAGATTCTCAGAACGGGACATAA

Domains

Predicted by InterproScan.

• Helix-turn-helix (HTH_3) (9-64)

• ComR tetratricopeptide (ComR_TPR) (73-296)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus mutans UA159	98.026	100	0.98
comR	Streptococcus infantarius subsp. infantarius ATCC BAA-102	52.431	94.737	0.497
comR	Streptococcus pyogenes MGAS8232	47.02	99.342	0.467
comR	Streptococcus pyogenes MGAS315	47.157	98.355	0.464
comR	Streptococcus suis P1/7	43.144	98.355	0.424
comR	Streptococcus suis 05ZYH33	43.144	98.355	0.424
comR	Streptococcus suis D9	36.667	98.684	0.362