Detailed information NTG0058125

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: SPN994038_RS09865
• Genome accession: NC_021026
• Coordinates: 1822172..1822633 (-)
• Length: 153 a.a.
• NCBI ID: WP_000250542.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae SPN994038
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1817172..1827633

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SPN994038_RS09830 (SPN994038_17910)	-	1817476..1818300 (-)	825	WP_001809383.1	membrane protein insertase YidC	-
SPN994038_RS09835 (SPN994038_17920)	rnpA	1818275..1818646 (-)	372	WP_000739244.1	ribonuclease P protein component	-
SPN994038_RS13270	-	1818663..1818794 (-)	132	WP_000768904.1	hypothetical protein	-
SPN994038_RS09840 (SPN994038_17930)	-	1818795..1819985 (-)	1191	WP_000167765.1	acetate kinase	-
SPN994038_RS09845 (SPN994038_17940)	comYH	1820036..1820989 (-)	954	WP_000345099.1	class I SAM-dependent methyltransferase	Machinery gene
SPN994038_RS11920 (SPN994038_17950)	-	1821050..1821644 (-)	595	Protein_1868	class I SAM-dependent methyltransferase	-
SPN994038_RS09860 (SPN994038_17960)	comGG/cglG	1821781..1822194 (-)	414	WP_000265624.1	competence type IV pilus minor pilin ComGG	Machinery gene
SPN994038_RS09865 (SPN994038_17970)	comGF/cglF	1822172..1822633 (-)	462	WP_000250542.1	competence type IV pilus minor pilin ComGF	Machinery gene
SPN994038_RS09870 (SPN994038_17980)	comGE/cglE	1822596..1822898 (-)	303	WP_000413382.1	competence type IV pilus minor pilin ComGE	Machinery gene
SPN994038_RS09875 (SPN994038_17990)	comGD/cglD	1822861..1823265 (-)	405	WP_000588013.1	competence type IV pilus minor pilin ComGD	Machinery gene
SPN994038_RS09880 (SPN994038_18000)	comGC/cglC	1823258..1823584 (-)	327	WP_000738636.1	comG operon protein ComGC	Machinery gene
SPN994038_RS09885 (SPN994038_18010)	comGB/cglB	1823586..1824602 (-)	1017	WP_074017570.1	competence type IV pilus assembly protein ComGB	Machinery gene
SPN994038_RS09890 (SPN994038_18020)	comGA/cglA/cilD	1824550..1825491 (-)	942	WP_000249552.1	competence type IV pilus ATPase ComGA	Machinery gene
SPN994038_RS09895 (SPN994038_18030)	-	1825567..1825932 (-)	366	WP_000286415.1	DUF1033 family protein	-
SPN994038_RS09900 (SPN994038_18040)	-	1826083..1827141 (-)	1059	WP_000649468.1	zinc-dependent alcohol dehydrogenase family protein	-

Sequence

Protein

• Length: 153 a.a.
• Molecular weight: 17918.53 Da
• Isoelectric Point: 9.3137

>NTDB_id=58125 SPN994038_RS09865 WP_000250542.1 1822172..1822633(-) (comGF/cglF) [Streptococcus pneumoniae SPN994038]
MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQTMSQLLISEVRYQQQSEQKEWLLFVDQLEAELDRSQFEKVEGN
RLYMKQDGKDIAIGKSKSDDFRKTNARGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEKS

Nucleotide

• Length: 462 bp

>NTDB_id=58125 SPN994038_RS09865 WP_000250542.1 1822172..1822633(-) (comGF/cglF) [Streptococcus pneumoniae SPN994038]
ATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAAGGTCAAGGCTTTTACCTTGTTAGAATCCCTACTTGCCCTCAT
TGTCATCAGTGGGGGATTACTCCTTTTTCAAACTATGAGTCAGCTCCTCATTTCAGAAGTTCGCTACCAGCAACAAAGCG
AGCAAAAGGAGTGGCTCTTGTTTGTGGATCAACTTGAGGCAGAATTAGACCGTTCGCAGTTCGAAAAAGTAGAAGGCAAT
CGCCTATACATGAAGCAAGATGGCAAGGACATCGCCATCGGTAAGTCAAAGTCAGACGATTTTCGTAAAACGAATGCTCG
TGGTCGAGGTTATCAGCCTATGGTTTATGGCCTCAAATCAGCTCAGATTACAGAGGACAATCAACTGGTTCATTTTCGTT
TCCAGTTTCAAAAAGGCTTAGAAAGGGAGTTCATCTATCGTGTGGAAAAAGAAAAAAGTTAA

Domains

Predicted by InterProScan.

• Putative Competence protein ComGF (ComGF) (45-141)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus pneumoniae Rx1	96.078	100	0.961
comGF/cglF	Streptococcus pneumoniae D39	96.078	100	0.961
comGF/cglF	Streptococcus pneumoniae R6	96.078	100	0.961
comGF/cglF	Streptococcus pneumoniae TIGR4	96.078	100	0.961
comGF/cglF	Streptococcus mitis SK321	92.157	100	0.922
comGF/cglF	Streptococcus mitis NCTC 12261	90.85	100	0.909