Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   I6L83_RS11725 Genome accession   NZ_CP077270
Coordinates   2408712..2409578 (-) Length   288 a.a.
NCBI ID   WP_011275951.1    Uniprot ID   -
Organism   Staphylococcus haemolyticus strain FDAARGOS 1453     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 2390912..2439245 2408712..2409578 within 0


Gene organization within MGE regions


Location: 2390912..2439245
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6L83_RS11655 (I6L83_11655) - 2392772..2394472 (-) 1701 WP_011275937.1 proline--tRNA ligase -
  I6L83_RS11660 (I6L83_11660) rseP 2394491..2395777 (-) 1287 WP_011275938.1 RIP metalloprotease RseP -
  I6L83_RS11665 (I6L83_11665) - 2395988..2396770 (-) 783 WP_037537321.1 phosphatidate cytidylyltransferase -
  I6L83_RS11670 (I6L83_11670) - 2396774..2397544 (-) 771 WP_011275940.1 isoprenyl transferase -
  I6L83_RS11675 (I6L83_11675) frr 2397770..2398324 (-) 555 WP_011275941.1 ribosome recycling factor -
  I6L83_RS11680 (I6L83_11680) pyrH 2398342..2399064 (-) 723 WP_011275942.1 UMP kinase -
  I6L83_RS11685 (I6L83_11685) tsf 2399201..2400079 (-) 879 WP_011275943.1 translation elongation factor Ts -
  I6L83_RS11690 (I6L83_11690) rpsB 2400237..2401025 (-) 789 WP_011275944.1 30S ribosomal protein S2 -
  I6L83_RS11695 (I6L83_11695) codY 2401292..2402065 (-) 774 WP_011275945.1 GTP-sensing pleiotropic transcriptional regulator CodY -
  I6L83_RS11700 (I6L83_11700) hslU 2402087..2403490 (-) 1404 WP_011275946.1 ATP-dependent protease ATPase subunit HslU -
  I6L83_RS11705 (I6L83_11705) hslV 2403549..2404094 (-) 546 WP_011275947.1 ATP-dependent protease subunit HslV -
  I6L83_RS11710 (I6L83_11710) xerC 2404095..2404988 (-) 894 WP_016930690.1 tyrosine recombinase XerC -
  I6L83_RS11715 (I6L83_11715) trmFO 2405133..2406440 (-) 1308 WP_011275949.1 FADH(2)-oxidizing methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))- methyltransferase TrmFO -
  I6L83_RS11720 (I6L83_11720) topA 2406464..2408533 (-) 2070 WP_011275950.1 type I DNA topoisomerase -
  I6L83_RS11725 (I6L83_11725) dprA 2408712..2409578 (-) 867 WP_011275951.1 DNA-processing protein DprA Machinery gene
  I6L83_RS11730 (I6L83_11730) - 2409797..2411026 (-) 1230 WP_011275952.1 aminoacyltransferase -
  I6L83_RS11735 (I6L83_11735) sucD 2411326..2412231 (-) 906 WP_011275953.1 succinate--CoA ligase subunit alpha -
  I6L83_RS11740 (I6L83_11740) sucC 2412253..2413419 (-) 1167 WP_011275954.1 ADP-forming succinate--CoA ligase subunit beta -
  I6L83_RS11745 (I6L83_11745) - 2413531..2414298 (-) 768 WP_033080068.1 ribonuclease HII -
  I6L83_RS11750 (I6L83_11750) ylqF 2414282..2415166 (-) 885 WP_011275956.1 ribosome biogenesis GTPase YlqF -
  I6L83_RS11755 (I6L83_11755) - 2415409..2418003 (+) 2595 WP_011275957.1 YfhO family protein -
  I6L83_RS11760 (I6L83_11760) - 2418005..2420614 (+) 2610 WP_037557998.1 YfhO family protein -
  I6L83_RS11765 (I6L83_11765) rplS 2420772..2421122 (-) 351 WP_037537864.1 50S ribosomal protein L19 -
  I6L83_RS11770 (I6L83_11770) trmD 2421227..2421964 (-) 738 WP_037557997.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -
  I6L83_RS11775 (I6L83_11775) rimM 2421964..2422467 (-) 504 WP_037557996.1 ribosome maturation factor RimM -
  I6L83_RS11780 (I6L83_11780) rpsP 2422586..2422861 (-) 276 WP_011275962.1 30S ribosomal protein S16 -
  I6L83_RS11785 (I6L83_11785) ffh 2423107..2424477 (-) 1371 WP_037557994.1 signal recognition particle protein -
  I6L83_RS11790 (I6L83_11790) - 2424503..2424835 (-) 333 WP_037537868.1 putative DNA-binding protein -
  I6L83_RS11795 (I6L83_11795) ftsY 2424822..2426045 (-) 1224 WP_053017389.1 signal recognition particle-docking protein FtsY -
  I6L83_RS11800 (I6L83_11800) smc 2426042..2429611 (-) 3570 WP_053017387.1 chromosome segregation protein SMC -
  I6L83_RS11805 (I6L83_11805) rnc 2429696..2430433 (-) 738 WP_011275967.1 ribonuclease III -
  I6L83_RS11810 (I6L83_11810) - 2430519..2430752 (-) 234 WP_001830184.1 acyl carrier protein -
  I6L83_RS11815 (I6L83_11815) fabG 2430865..2431602 (-) 738 WP_011275968.1 3-oxoacyl-[acyl-carrier-protein] reductase -
  I6L83_RS11820 (I6L83_11820) fabD 2431592..2432521 (-) 930 WP_011275969.1 ACP S-malonyltransferase -
  I6L83_RS11825 (I6L83_11825) plsX 2432514..2433500 (-) 987 WP_011275970.1 phosphate acyltransferase PlsX -
  I6L83_RS11830 (I6L83_11830) fapR 2433502..2434062 (-) 561 WP_011275971.1 transcription factor FapR -
  I6L83_RS11835 (I6L83_11835) recG 2434198..2436249 (-) 2052 WP_016930693.1 ATP-dependent DNA helicase RecG -
  I6L83_RS11840 (I6L83_11840) - 2436404..2437204 (-) 801 WP_011275973.1 thermonuclease family protein -
  I6L83_RS11845 (I6L83_11845) fakA 2437390..2439048 (-) 1659 WP_011275974.1 fatty acid kinase catalytic subunit FakA -

Sequence

Protein


Download         Length: 288 a.a.        Molecular weight: 33058.12 Da        Isoelectric Point: 9.4081

>NTDB_id=580528 I6L83_RS11725 WP_011275951.1 2408712..2409578(-) (dprA) [Staphylococcus haemolyticus strain FDAARGOS 1453]
MTNNNILLLKLIWLGYTTQHIHHLLKLNPEFFKFSYTDQIDSIKNWDKLFHKGDFIDRYNHLNDKEILSFLNQHKISFVT
PFNANYPRLLKEIYDYPFVLFYQGDPQLLTSPNTLGVVGSRNATEYSAKAMQYLFPKFKQIPLTIISGLAKGADSIAHHF
AIEYQLPTIAVLGFGHMMHYPRETQKLRNIIEVKGLVISEYPPFTSVRRYHFPQRNRLISGLSQGVLITEASVRSGSQIT
IDCALDQNRNIYVLPGSIFNPLTKGNLKRAQEGAMIVTSADDILCDYK

Nucleotide


Download         Length: 867 bp        

>NTDB_id=580528 I6L83_RS11725 WP_011275951.1 2408712..2409578(-) (dprA) [Staphylococcus haemolyticus strain FDAARGOS 1453]
ATGACTAACAACAACATATTACTTTTGAAATTAATTTGGTTAGGTTATACGACCCAACATATTCATCATTTATTAAAATT
AAATCCTGAATTTTTTAAATTCTCTTATACTGATCAAATAGATTCAATAAAAAATTGGGACAAGTTATTTCATAAAGGTG
ATTTTATTGATCGATATAATCATTTAAATGATAAAGAAATTTTGTCATTTTTGAATCAACACAAGATAAGTTTTGTAACA
CCGTTTAACGCTAATTATCCTCGACTATTAAAAGAAATTTATGATTATCCGTTTGTCCTATTTTACCAAGGTGACCCCCA
ATTATTAACATCCCCCAATACATTAGGTGTGGTGGGCTCAAGAAATGCAACAGAGTACTCAGCTAAAGCCATGCAATACT
TATTTCCTAAATTTAAACAAATTCCACTAACCATTATTTCCGGTTTGGCAAAAGGTGCTGATAGCATTGCACATCATTTT
GCTATAGAGTATCAATTACCTACTATAGCTGTTTTAGGTTTTGGTCATATGATGCATTACCCTAGAGAAACGCAAAAATT
ACGCAACATAATTGAAGTAAAAGGTTTAGTTATTAGTGAATATCCGCCATTCACTAGTGTTAGGCGATATCACTTTCCGC
AACGCAATCGTTTGATAAGCGGTCTTTCACAAGGGGTTTTAATAACTGAAGCAAGTGTTAGAAGCGGTAGTCAAATTACA
ATTGATTGCGCATTAGACCAAAATAGAAATATATATGTATTACCAGGTTCAATATTTAATCCACTAACTAAAGGTAATTT
GAAACGAGCTCAAGAAGGTGCGATGATTGTAACCTCAGCTGATGATATTCTATGTGATTATAAATAG

Domains

Predicted by InterproScan.

DNA recombination-mediator protein A (DNA_processg_A)

(72-278)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Staphylococcus aureus MW2

49.825

98.958

0.493
  dprA Staphylococcus aureus N315

49.825

98.958

0.493
  dprA/cilB/dalA Streptococcus pneumoniae Rx1

36.395

100

0.372
  dprA/cilB/dalA Streptococcus pneumoniae D39

36.395

100

0.372
  dprA/cilB/dalA Streptococcus pneumoniae R6

36.395

100

0.372
  dprA/cilB/dalA Streptococcus pneumoniae TIGR4

36.395

100

0.372
  dprA Streptococcus mutans UA159

37.544

98.958

0.372
  dprA/cilB/dalA Streptococcus mitis SK321

35.374

100

0.361
  dprA Legionella pneumophila strain ERS1305867

42.105

85.764

0.361