Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/comD1   Type   Regulator
Locus tag   I6L85_RS00070 Genome accession   NZ_CP077248
Coordinates   13089..14450 (+) Length   453 a.a.
NCBI ID   WP_269459934.1    Uniprot ID   -
Organism   Streptococcus gordonii strain FDAARGOS 1455     
Function   phosphorylation of ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 8089..19450
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6L85_RS00040 (I6L85_00040) dnaA 8375..9727 (-) 1353 WP_111723071.1 chromosomal replication initiator protein DnaA -
  I6L85_RS00045 (I6L85_00045) spo0J 9930..10694 (-) 765 WP_111724269.1 ParB/RepB/Spo0J family partition protein Regulator
  I6L85_RS00050 (I6L85_00050) htrA 10760..11953 (-) 1194 WP_111724268.1 S1C family serine protease Regulator
  I6L85_RS00055 (I6L85_00055) rlmH 12147..12626 (+) 480 WP_008808034.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  I6L85_RS00065 (I6L85_00065) comC/comC1 12912..13076 (+) 165 WP_080998577.1 bacteriocin Regulator
  I6L85_RS00070 (I6L85_00070) comD/comD1 13089..14450 (+) 1362 WP_269459934.1 competence system sensor histidine kinase ComD Regulator
  I6L85_RS00075 (I6L85_00075) comE/comE2 14447..15214 (+) 768 WP_008808031.1 competence system response regulator transcription factor ComE Regulator
  I6L85_RS00090 (I6L85_00090) ychF 15536..16651 (+) 1116 WP_008808030.1 redox-regulated ATPase YchF -
  I6L85_RS00095 (I6L85_00095) pth 16724..17293 (+) 570 WP_111724267.1 aminoacyl-tRNA hydrolase -

Sequence

Protein


Download         Length: 453 a.a.        Molecular weight: 52726.18 Da        Isoelectric Point: 5.5158

>NTDB_id=580229 I6L85_RS00070 WP_269459934.1 13089..14450(+) (comD/comD1) [Streptococcus gordonii strain FDAARGOS 1455]
MMNFEKIFAIFSLLVQTISFVTVYKKICDIKKLNISIIFLYLTISFSSLILAQFYNLLPEYGDVLSTFLHYLLIFFQPLI
LHLYFSKKGLYKGYVSIFLSLLIYLSVSSSETFFSVIISSVTGDDFVNQYWGSYYTIVNILALFFVLKSFEFFEFEFSYF
KNFDFEKEIMNVIKIYVTIHILLNISHWFSENAHLNSFASMIATIGFIMFLSTLFYLKSAREQYEKAKEIQQKKEEQRQL
QLYTDEIVGLYNEIRGFRHDYAGMLTSLQTGINSGDMKEVERIFHNVLSQANISLRSDDYTFFELNNVQDTALRSVLIQT
IFKARECGVEIVFEMKDVIGTLPMKLLDLVRVASVLLNNAVEGAAESPSKTMNVSLVKLDKEIVFVIQNSRQSRYINLEE
IYEVGFSTKGENRGLGLNNVKEIIDKYDEVILETDIETNYFIQVVRFKRKEQI

Nucleotide


Download         Length: 1362 bp        

>NTDB_id=580229 I6L85_RS00070 WP_269459934.1 13089..14450(+) (comD/comD1) [Streptococcus gordonii strain FDAARGOS 1455]
ATGATGAATTTTGAAAAAATATTTGCTATTTTCTCTTTACTAGTTCAAACAATTTCTTTTGTTACTGTATACAAAAAAAT
ATGTGATATAAAAAAATTAAATATTTCTATCATATTTCTGTACTTAACAATAAGTTTTAGTAGTTTGATATTAGCACAGT
TTTATAATTTATTACCCGAATATGGAGATGTATTAAGTACTTTCTTACATTACTTACTTATATTTTTCCAACCACTAATC
TTACATTTATATTTTTCTAAAAAAGGATTATATAAAGGATATGTATCTATCTTTTTATCCTTACTTATATATCTTTCTGT
ATCATCTTCTGAAACTTTTTTCTCAGTTATTATATCTTCAGTGACAGGAGATGATTTTGTTAATCAATACTGGGGTTCTT
ACTATACTATAGTAAATATCTTAGCATTATTTTTTGTTTTGAAATCTTTTGAATTTTTTGAGTTTGAATTTAGTTATTTT
AAAAATTTTGATTTTGAAAAAGAAATAATGAATGTAATTAAAATTTATGTAACGATTCATATCTTATTAAATATTTCTCA
TTGGTTCAGCGAAAATGCACATCTTAATAGCTTTGCTAGTATGATTGCAACTATAGGATTTATTATGTTTTTGTCGACCT
TATTTTATCTGAAGTCTGCTCGTGAACAATATGAAAAAGCTAAAGAAATTCAGCAAAAAAAGGAAGAACAAAGACAACTA
CAACTTTATACAGATGAAATTGTAGGTCTTTATAACGAAATTCGAGGTTTTCGTCATGATTATGCTGGTATGTTAACAAG
TTTACAAACAGGAATTAACTCAGGTGATATGAAAGAAGTAGAGAGAATCTTTCATAATGTTTTAAGTCAAGCTAATATTT
CCCTTCGATCAGATGACTATACTTTTTTTGAGTTAAATAATGTTCAAGACACTGCCTTGAGAAGTGTGCTAATTCAAACT
ATATTTAAGGCTCGAGAGTGTGGAGTAGAGATCGTATTTGAAATGAAGGATGTTATTGGGACATTACCTATGAAACTTTT
AGATTTAGTTCGAGTAGCTAGTGTATTGCTCAATAATGCGGTTGAAGGGGCAGCTGAAAGTCCCTCAAAAACAATGAACG
TGTCTTTAGTAAAGCTAGATAAAGAAATTGTTTTTGTAATTCAGAATTCTCGTCAAAGCCGTTATATTAATTTAGAAGAA
ATTTATGAAGTAGGCTTCTCAACAAAAGGAGAAAATCGAGGATTAGGTTTAAATAATGTCAAAGAAATTATTGACAAATA
TGATGAAGTTATTCTGGAAACAGATATAGAAACAAATTATTTTATACAAGTTGTAAGATTTAAAAGAAAGGAACAAATAT
GA

Domains

Predicted by InterproScan.

GHKL domain (HATPase_c_5)

(344-445)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/comD1 Streptococcus gordonii str. Challis substr. CH1

76.6

100

0.766
  comD/comD2 Streptococcus gordonii strain NCTC7865

77.405

98.675

0.764
  comD/comD2 Streptococcus pneumoniae TIGR4

49.34

83.664

0.413
  comD/comD1 Streptococcus pneumoniae Rx1

49.077

83.664

0.411
  comD/comD1 Streptococcus pneumoniae D39

49.077

83.664

0.411
  comD/comD1 Streptococcus pneumoniae R6

49.077

83.664

0.411
  comD Streptococcus mitis NCTC 12261

48.285

83.664

0.404
  comD Streptococcus mitis SK321

48.404

83.002

0.402