Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Regulator
Locus tag   SPN032672_RS06525 Genome accession   NC_021003
Coordinates   1208772..1210121 (+) Length   449 a.a.
NCBI ID   WP_041178987.1    Uniprot ID   -
Organism   Streptococcus pneumoniae SPN032672     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 1203772..1215121
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPN032672_RS06495 plsX 1203890..1204882 (+) 993 WP_000717456.1 phosphate acyltransferase PlsX -
  SPN032672_RS06500 - 1204888..1205121 (+) 234 WP_000136449.1 acyl carrier protein -
  SPN032672_RS12025 - 1205158..1205458 (+) 301 Protein_1191 transposase family protein -
  SPN032672_RS06505 blpU 1205661..1205891 (+) 231 WP_001093075.1 bacteriocin-like peptide BlpU -
  SPN032672_RS13985 - 1205894..1206019 (+) 126 WP_000346297.1 PncF family bacteriocin immunity protein -
  SPN032672_RS06520 comA 1206606..1208759 (+) 2154 WP_000668299.1 peptide cleavage/export ABC transporter ComA Regulator
  SPN032672_RS06525 comB 1208772..1210121 (+) 1350 WP_041178987.1 competence pheromone export protein ComB Regulator
  SPN032672_RS06530 purC 1210292..1210999 (+) 708 WP_000043304.1 phosphoribosylaminoimidazolesuccinocarboxamide synthase -
  SPN032672_RS14145 - 1211001..1211144 (+) 144 WP_050167432.1 hypothetical protein -
  SPN032672_RS06535 - 1211201..1214926 (+) 3726 WP_000361174.1 phosphoribosylformylglycinamidine synthase -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 49601.42 Da        Isoelectric Point: 5.2477

>NTDB_id=57893 SPN032672_RS06525 WP_041178987.1 1208772..1210121(+) (comB) [Streptococcus pneumoniae SPN032672]
MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKEMSLSTRATVEPSRILANIQSTSNNRILVNHLEENKL
VKKGDLLVQYQEGAEGVQAESYASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
ETIASQNAAASQTQAEIGNLISQTEAKIRDYQTAKSAMETGASLASQNLAYSLYQSYKSQGEENPQTKVQAVAQVEAQIS
QLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQHLAKVGQELTLLAQKILEAESGKNVQGNLLDKGKITASEDGVLH
LNPETSDSSMVAEGALLAQLYPSLEREGKAKLTAYLSSKDVARIKVGDSVRYTTTHDAGNQLFLDSTITSIDATATKTEK
GNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=57893 SPN032672_RS06525 WP_041178987.1 1208772..1210121(+) (comB) [Streptococcus pneumoniae SPN032672]
ATGAAACCAGAATTTTTAGAAAGTGCGGAGTTTTATAATCGTCGTTACCATAATTTTTCCAGTAGTGTGATTGTACCCAT
GGCCCTTCTGCTCGTGTTTTTACTTGGCTTTGCAACTGTTGCAGAGAAGGAGATGAGTTTGTCCACTAGAGCTACTGTCG
AACCCAGTCGTATCCTTGCAAATATCCAGTCAACTAGCAACAATCGTATTCTTGTCAATCATTTGGAAGAAAATAAGCTG
GTTAAGAAGGGGGATCTCTTGGTTCAATACCAAGAAGGGGCAGAGGGTGTCCAAGCGGAGTCCTATGCCAGTCAGTTGGA
CATGCTAAAGGATCAAAAAAAGCAATTGGAGTATCTGCAAAAGAGCCTGCAAGAAGGGGAGAACCACTTTCCAGAGGAGG
ATAAGTTTGGCTACCAAGCCACCTTTCGCGACTACATCAGTCAAGCAGGCAGTCTTAGGGCTAGTACATCGCAACAAAAT
GAGACCATCGCGTCCCAGAATGCAGCAGCTAGCCAAACCCAAGCCGAAATCGGCAACCTCATCAGTCAAACAGAGGCTAA
AATTCGCGATTACCAGACAGCTAAGTCAGCTATGGAAACAGGTGCTTCCTTGGCCAGTCAGAATCTAGCCTACTCTCTTT
ACCAGTCCTACAAGTCTCAGGGCGAGGAAAATCCCCAAACTAAGGTTCAGGCAGTTGCACAGGTTGAAGCACAGATTTCT
CAGTTAGAATCTAGTCTTGCTACTTACCGTGTCCAGTATGCAGGTTCAGGTACCCAGCAAGCCTATGCGTCAGGGTTAAG
CAGTCAATTGGAATCCCTTAAATCCCAACATTTGGCAAAGGTTGGTCAGGAATTGACCCTTCTAGCCCAGAAAATCTTGG
AGGCAGAGTCAGGTAAGAATGTACAGGGAAATCTTTTAGACAAGGGGAAAATTACGGCGAGTGAGGATGGGGTGCTTCAT
CTTAATCCTGAGACCAGTGATTCTAGCATGGTTGCAGAAGGTGCCCTACTAGCCCAACTTTATCCATCTTTGGAAAGAGA
AGGGAAAGCCAAACTCACAGCCTATCTAAGTTCAAAAGATGTAGCAAGAATCAAGGTCGGTGATTCTGTTCGCTATACTA
CGACTCATGATGCCGGGAATCAACTTTTCCTAGATTCTACTATTACAAGTATTGATGCGACAGCTACTAAGACTGAGAAA
GGGAATTTCTTTAAAATCGAGGCGGAGACTAATCTAACTTCGGAGCAGGCTGAAAAACTTAGGTACGGGGTGGAAGGCCG
CTTGCAGATGATTACGGGCAAGAAAAGTTATCTACGTTATTATTTGGATCAATTTTTGAACAAAGAGTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Streptococcus pneumoniae TIGR4

98.886

100

0.989
  comB Streptococcus pneumoniae Rx1

98.664

100

0.987
  comB Streptococcus pneumoniae D39

98.664

100

0.987
  comB Streptococcus pneumoniae R6

98.664

100

0.987
  comB Streptococcus mitis SK321

94.878

100

0.949
  comB Streptococcus mitis NCTC 12261

94.432

100

0.944
  comB Streptococcus gordonii str. Challis substr. CH1

55.111

100

0.552

Multiple sequence alignment