Detailed information NTG0057892

Bioinformatically predicted

Overview

• Name: comA
• Type: Regulator
• Locus tag: SPN032672_RS06520
• Genome accession: NC_021003
• Coordinates: 1206606..1208759 (+)
• Length: 717 a.a.
• NCBI ID: WP_000668299.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae SPN032672
• Function: processing and transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 1201606..1213759

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SPN032672_RS06485	-	1201957..1203126 (+)	1170	WP_000366376.1	pyridoxal phosphate-dependent aminotransferase	-
SPN032672_RS06490	recO	1203123..1203893 (+)	771	WP_000616164.1	DNA repair protein RecO	-
SPN032672_RS06495	plsX	1203890..1204882 (+)	993	WP_000717456.1	phosphate acyltransferase PlsX	-
SPN032672_RS06500	-	1204888..1205121 (+)	234	WP_000136449.1	acyl carrier protein	-
SPN032672_RS12025	-	1205158..1205458 (+)	301	Protein_1191	transposase family protein	-
SPN032672_RS06505	blpU	1205661..1205891 (+)	231	WP_001093075.1	bacteriocin-like peptide BlpU	-
SPN032672_RS13985	-	1205894..1206019 (+)	126	WP_000346297.1	PncF family bacteriocin immunity protein	-
SPN032672_RS06520	comA	1206606..1208759 (+)	2154	WP_000668299.1	peptide cleavage/export ABC transporter ComA	Regulator
SPN032672_RS06525	comB	1208772..1210121 (+)	1350	WP_041178987.1	competence pheromone export protein ComB	Regulator
SPN032672_RS06530	purC	1210292..1210999 (+)	708	WP_000043304.1	phosphoribosylaminoimidazolesuccinocarboxamide synthase	-
SPN032672_RS14145	-	1211001..1211144 (+)	144	WP_050167432.1	hypothetical protein	-

Sequence

Protein

• Length: 717 a.a.
• Molecular weight: 80352.36 Da
• Isoelectric Point: 6.2590

>NTDB_id=57892 SPN032672_RS06520 WP_000668299.1 1206606..1208759(+) (comA) [Streptococcus pneumoniae SPN032672]
MKFGKRHYRPQVDQMDCGVASLAMVFGYYGSYYFLAHLRELAKTTMDGTTALGLVKVAEEIGFETRAIKADMTLFDLPDL
TFPFVAHVLKEGKLLHYYVVTGQDKDSIHIADPDPGVKLTKLPRERFEEEWTGVTLFMAPSPDYKPYKEQKNGLLSFIPI
LVKQRGLIANIVLATLLVTGINIVGSYYLQSIIDTYVPDQMRSTLGIISIGLVIVYILQQILSYAQEYLLLVLGQRLSID
VILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSIIDALASTILSIFLDVSTVVIISLVLFSQNTNLFFMTLLALPIYTV
IIFAFMKPFEKMNRDTMEANAVLSSSIIEDINGIETIKSLTSESQRYQKIDKEFVDYLKKSFTYSRAESQQKALKKVAHL
LLNVGILWMGAVLVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQTAQVANNRLNEVYLVASEFEEKKTVEDLSLM
KGDMTFKQVHYKYGYGRDVLSDINLTVPQGSKVAFVGISGSGKTTLAKMMVNFYDPSQGEISLGGVNLNQIDKKALRQYI
NYLPQQPYVFNGTILENLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISGGQRQRIALARALLTDA
PVLILDEATSSLDILTEKRIVDNLMALDKTLIFIAHRLTIAERTEKVVVLDQGKIVEEGKHADLLAQGGFYAHLVNS

Nucleotide

• Length: 2154 bp

>NTDB_id=57892 SPN032672_RS06520 WP_000668299.1 1206606..1208759(+) (comA) [Streptococcus pneumoniae SPN032672]
ATGAAATTTGGGAAACGTCACTATCGTCCGCAAGTGGATCAGATGGACTGCGGTGTAGCTTCATTAGCCATGGTTTTTGG
CTACTATGGTAGTTATTATTTTTTGGCTCACTTGCGAGAATTGGCTAAGACGACCATGGATGGGACGACGGCTTTGGGCT
TGGTCAAGGTGGCAGAGGAGATTGGTTTTGAGACGCGAGCCATTAAGGCGGATATGACGCTTTTTGACTTGCCGGATTTG
ACTTTTCCTTTTGTTGCCCATGTGCTTAAGGAAGGGAAATTGCTCCACTACTATGTGGTGACTGGGCAGGATAAGGATAG
CATTCATATTGCCGATCCAGATCCCGGGGTGAAGTTGACTAAACTGCCACGTGAGCGTTTTGAGGAAGAATGGACAGGAG
TGACTCTTTTTATGGCACCTAGTCCAGACTATAAGCCTTATAAGGAACAAAAAAATGGTCTGCTCTCTTTTATCCCTATA
TTAGTGAAGCAGCGTGGCTTGATTGCCAATATCGTTTTGGCAACACTCTTGGTAACCGGGATTAACATTGTGGGTTCTTA
TTATCTGCAGTCTATCATTGATACCTATGTGCCAGATCAGATGCGTTCGACACTAGGGATTATTTCTATTGGGCTAGTCA
TCGTCTACATCCTCCAGCAAATCTTGTCTTACGCTCAGGAGTATCTCTTGCTTGTTTTGGGGCAACGCTTGTCGATTGAC
GTGATTTTGTCCTATATCAAGCATGTTTTTCACCTCCCTATGTCCTTCTTTGCGACACGCAGGACAGGGGAGATCGTGTC
TCGTTTTACAGATGCTAACAGTATCATCGATGCGCTGGCTTCGACCATCCTTTCGATTTTCCTAGATGTGTCAACGGTTG
TCATTATTTCCCTTGTTCTATTTTCACAAAATACCAATCTCTTTTTCATGACTTTATTGGCGCTTCCTATCTACACAGTG
ATTATCTTTGCCTTTATGAAGCCGTTTGAAAAGATGAATCGGGATACCATGGAAGCCAATGCGGTTCTGTCTTCTTCTAT
CATTGAGGACATCAACGGTATTGAGACTATCAAGTCCTTGACCAGTGAAAGTCAGCGTTACCAAAAAATTGACAAGGAAT
TTGTGGATTATCTGAAGAAATCCTTTACCTATAGTCGAGCAGAGAGTCAGCAAAAGGCTCTGAAAAAGGTTGCCCATCTC
TTGCTTAATGTCGGCATTCTCTGGATGGGGGCTGTTCTGGTCATGGATGGCAAGATGAGTTTGGGGCAGTTGATTACCTA
TAATACCTTGCTGGTTTACTTTACCAATCCTTTGGAAAATATCATCAATCTGCAAACCAAGCTTCAGACAGCGCAGGTTG
CCAATAACCGTCTAAATGAAGTGTATCTAGTAGCTTCTGAGTTTGAGGAGAAGAAAACAGTTGAGGATTTGAGCTTGATG
AAGGGAGATATGACCTTCAAGCAGGTTCATTACAAGTATGGCTATGGTCGAGACGTCTTGTCGGATATCAATTTAACCGT
TCCCCAAGGGTCTAAGGTGGCTTTTGTGGGGATTTCAGGGTCAGGTAAGACGACTTTGGCCAAGATGATGGTTAATTTTT
ACGACCCAAGTCAAGGGGAGATTAGTCTGGGTGGTGTCAATCTCAATCAGATTGATAAAAAAGCCCTGCGCCAGTACATC
AACTATCTGCCTCAACAGCCCTATGTCTTTAACGGAACGATTTTGGAGAATCTTCTTTTGGGAGCCAAGGAGGGGACGAC
ACAGGAAGATATCTTACGGGCGGTCGAATTGGCAGAGATTCGAGAGGATATCGAGCGCATGCCACTGAATTATCAGACAG
AATTGACTTCGGATGGGGCAGGGATTTCAGGTGGTCAACGTCAGAGAATCGCTTTGGCGCGTGCTCTCTTGACAGATGCG
CCGGTCTTGATTTTGGATGAGGCGACTAGCAGTTTGGATATTTTGACAGAGAAGCGGATTGTCGATAATCTCATGGCTTT
GGACAAGACCTTGATTTTCATTGCTCACCGCTTGACTATTGCTGAGCGGACAGAGAAGGTGGTTGTCTTGGATCAGGGCA
AGATTGTCGAAGAAGGAAAGCATGCTGATTTGCTTGCACAGGGAGGCTTTTACGCCCATTTGGTCAATAGCTAG

Domains

Predicted by InterproScan.

• ABC transporter transmembrane region (ABC_membrane) (170-438)

• Peptidase C39 family (Peptidase_C39) (7-142)

• ABC transporter (ABC_tran) (500-650)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Streptococcus pneumoniae D39	99.582	100	0.996
comA	Streptococcus pneumoniae R6	99.582	100	0.996
comA	Streptococcus pneumoniae Rx1	99.582	100	0.996
comA	Streptococcus pneumoniae TIGR4	99.163	100	0.992
comA	Streptococcus mitis NCTC 12261	98.466	100	0.985
comA	Streptococcus mitis SK321	98.326	100	0.983
comA	Streptococcus gordonii str. Challis substr. CH1	80.753	100	0.808
comA/nlmT	Streptococcus mutans UA159	64.714	100	0.647