Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Regulator
Locus tag   KQ224_RS06405 Genome accession   NZ_CP076721
Coordinates   1246343..1247695 (-) Length   450 a.a.
NCBI ID   WP_174846492.1    Uniprot ID   -
Organism   Streptococcus parasuis strain H35     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 1241343..1252695
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KQ224_RS06370 (KQ224_06370) - 1242058..1242717 (+) 660 WP_171989053.1 amino acid ABC transporter permease -
  KQ224_RS06375 (KQ224_06375) - 1242698..1243375 (+) 678 WP_171989020.1 amino acid ABC transporter permease -
  KQ224_RS06380 (KQ224_06380) - 1243380..1244126 (+) 747 WP_216806249.1 amino acid ABC transporter ATP-binding protein -
  KQ224_RS06385 (KQ224_06385) - 1244139..1245008 (+) 870 WP_130555553.1 cysteine ABC transporter substrate-binding protein -
  KQ224_RS06390 (KQ224_06390) - 1245367..1245558 (-) 192 WP_024392851.1 hypothetical protein -
  KQ224_RS06395 (KQ224_06395) - 1245575..1245775 (-) 201 WP_239604410.1 hypothetical protein -
  KQ224_RS06400 (KQ224_06400) - 1245776..1245955 (-) 180 WP_024392853.1 hypothetical protein -
  KQ224_RS06405 (KQ224_06405) comB 1246343..1247695 (-) 1353 WP_174846492.1 bacteriocin secretion accessory protein Regulator
  KQ224_RS06410 (KQ224_06410) comA 1247707..1249860 (-) 2154 WP_174846491.1 peptide cleavage/export ABC transporter ComA Regulator
  KQ224_RS06415 (KQ224_06415) - 1250280..1250447 (-) 168 WP_216806250.1 hypothetical protein -
  KQ224_RS06420 (KQ224_06420) - 1250468..1250638 (-) 171 WP_216806251.1 bacteriocin -

Sequence

Protein


Download         Length: 450 a.a.        Molecular weight: 50870.57 Da        Isoelectric Point: 4.8303

>NTDB_id=577586 KQ224_RS06405 WP_174846492.1 1246343..1247695(-) (comB) [Streptococcus parasuis strain H35]
MDHHLLESAEFYNRRYHNAASRVIIPSCILFLFLILFSIVAKKEMTISTRATVEPVQRLAQIHSISNHQILRNHLFENQE
ISVGDLLVEYQSENEQIQEDKIKENIAVLKNQISQLNVLKKSLESGSNQFEKEDQYGYSQMFKDYCYQLETLASTIDQQN
VTIASQNQAAKQSQLELDKVMHQTEKALADYRELKWAIRSDGVIDEENVGYSIYAQYQVAQSEDAVASQESFIAQIDNQI
SQVETQLASYKLQYASAGVQQSYTNSLDSQSASLKAQYLTKVGQEMTLLSSQLRELEATLTVQKQAMDKTKIIADQAGVV
HLNTEVEGSMMIPEGTIIADVYPVLMEAKKMKITAYIPSKDIASISLKDNIQFSIQGKGVKRLALQSNISEIASTAIQTE
AGNFFKVEAETRISTEMAEQLRYGMEGQFVVITGKKTYFQYFIDEFLGKE

Nucleotide


Download         Length: 1353 bp        

>NTDB_id=577586 KQ224_RS06405 WP_174846492.1 1246343..1247695(-) (comB) [Streptococcus parasuis strain H35]
ATGGACCATCATCTGTTAGAAAGTGCAGAATTTTACAACAGACGTTATCATAATGCAGCCAGTAGAGTGATTATTCCTAG
TTGTATATTGTTTTTGTTTCTCATTCTTTTTTCAATCGTTGCTAAAAAAGAAATGACCATTTCAACAAGAGCAACCGTAG
AACCTGTACAACGATTAGCACAGATTCACTCAATCAGTAATCATCAGATTCTTAGGAATCATTTATTCGAAAATCAAGAG
ATTTCAGTTGGAGATTTATTGGTAGAATATCAATCAGAGAATGAGCAAATCCAAGAAGACAAGATCAAAGAAAACATAGC
TGTTTTGAAAAATCAGATTTCTCAACTCAATGTCTTGAAGAAAAGTTTAGAATCGGGAAGTAATCAATTTGAGAAAGAAG
ATCAATATGGTTATTCTCAAATGTTTAAGGATTATTGCTATCAATTAGAAACATTAGCAAGTACGATTGACCAACAAAAT
GTAACGATTGCATCTCAAAATCAAGCTGCAAAACAATCACAATTGGAATTGGATAAAGTAATGCATCAAACGGAGAAAGC
CTTAGCAGACTATAGAGAATTGAAATGGGCCATTCGGTCTGATGGTGTCATTGATGAGGAGAATGTTGGCTATTCAATCT
ATGCACAGTATCAGGTAGCACAATCAGAGGATGCAGTTGCCAGTCAAGAATCATTCATCGCTCAAATCGATAATCAAATC
AGTCAAGTAGAGACTCAACTGGCCAGTTATAAATTGCAATATGCCAGTGCAGGAGTGCAACAATCGTATACGAATAGCTT
GGATAGTCAGTCGGCATCGTTGAAAGCTCAATATTTAACCAAGGTTGGTCAGGAAATGACCTTGTTGTCTTCTCAATTAA
GAGAACTAGAAGCGACACTTACGGTTCAAAAACAAGCAATGGATAAGACAAAAATTATTGCTGATCAGGCAGGGGTCGTT
CATTTAAATACAGAAGTTGAGGGCTCAATGATGATTCCAGAAGGAACAATTATTGCAGATGTTTATCCAGTTCTAATGGA
AGCTAAGAAAATGAAGATTACAGCATATATTCCTTCGAAAGATATTGCAAGCATCTCATTAAAGGATAATATCCAGTTTT
CAATACAAGGGAAGGGAGTTAAGCGACTAGCACTGCAGTCCAACATATCAGAAATTGCAAGTACTGCCATTCAAACGGAA
GCTGGTAATTTTTTCAAAGTTGAAGCAGAAACCAGAATATCAACAGAAATGGCTGAACAATTGAGGTATGGAATGGAAGG
CCAATTTGTCGTGATTACAGGTAAGAAGACGTATTTTCAATATTTCATAGATGAATTTTTAGGTAAGGAATAG

Domains

Predicted by InterproScan.

HlyD family secretion protein (HlyD_3)

(312-424)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Streptococcus gordonii str. Challis substr. CH1

48.552

99.778

0.484
  comB Streptococcus pneumoniae D39

47.333

100

0.473
  comB Streptococcus pneumoniae R6

47.333

100

0.473
  comB Streptococcus pneumoniae Rx1

47.333

100

0.473
  comB Streptococcus pneumoniae TIGR4

46.889

100

0.469
  comB Streptococcus mitis NCTC 12261

46

100

0.46
  comB Streptococcus mitis SK321

45.778

100

0.458