Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   KQ224_RS06410 Genome accession   NZ_CP076721
Coordinates   1247707..1249860 (-) Length   717 a.a.
NCBI ID   WP_174846491.1    Uniprot ID   -
Organism   Streptococcus parasuis strain H35     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 1242707..1254860
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KQ224_RS06380 (KQ224_06380) - 1243380..1244126 (+) 747 WP_216806249.1 amino acid ABC transporter ATP-binding protein -
  KQ224_RS06385 (KQ224_06385) - 1244139..1245008 (+) 870 WP_130555553.1 cysteine ABC transporter substrate-binding protein -
  KQ224_RS06390 (KQ224_06390) - 1245367..1245558 (-) 192 WP_024392851.1 hypothetical protein -
  KQ224_RS06395 (KQ224_06395) - 1245575..1245775 (-) 201 WP_239604410.1 hypothetical protein -
  KQ224_RS06400 (KQ224_06400) - 1245776..1245955 (-) 180 WP_024392853.1 hypothetical protein -
  KQ224_RS06405 (KQ224_06405) comB 1246343..1247695 (-) 1353 WP_174846492.1 bacteriocin secretion accessory protein Regulator
  KQ224_RS06410 (KQ224_06410) comA 1247707..1249860 (-) 2154 WP_174846491.1 peptide cleavage/export ABC transporter ComA Regulator
  KQ224_RS06415 (KQ224_06415) - 1250280..1250447 (-) 168 WP_216806250.1 hypothetical protein -
  KQ224_RS06420 (KQ224_06420) - 1250468..1250638 (-) 171 WP_216806251.1 bacteriocin -
  KQ224_RS06435 (KQ224_06435) - 1254408..1254860 (-) 453 WP_216806253.1 HIT family protein -

Sequence

Protein


Download         Length: 717 a.a.        Molecular weight: 81143.44 Da        Isoelectric Point: 7.2217

>NTDB_id=577587 KQ224_RS06410 WP_174846491.1 1247707..1249860(-) (comA) [Streptococcus parasuis strain H35]
MKFGKRHYRAQVDTRDCGVAALAMILEYYRSHHSLASLREMAKTTMEGTTAFGLVKVAEELGFETRAIKADMSLFSMREA
VYPFIAHVVKDGTLLHYYVVIGADKKYIYIADPDPSVKLTKLSHEQFEKEWTGVSLFMAPKPEYQPHKEKSHGLLSFIPL
LTKQKGLITNIVLATLLVTFINIVGSYYLQSIIDTYVPNQMKTTLGVISVGLVVVYALQQLLSYAQEYLLIILGQRLSID
VILSYIRHVFHLPMSFFATRRTGEIVSRFTDANSIIDALASTILSIFLDVSIVVVVSVVLFSQNVYLFFISLLALPIYTL
IIFAFMKPFEKMNQEVMESNAILSSSIIEDINGIETIKSLTSEKQRYQKIDREFVDYLQKSFAYNKAEGQQKVLKRLAQL
VLNVAILWLGACLVMDHKMTLGQLITFNTLLVYFTNPLENIINLQTKLQTAQVANTRLNEVYLVESEFAEKKSVTDLSLL
SGDIECNKVHYKYGYGRDVLTDINLKIKRGEKVSFVGVSGSGKTTLAKMMVDFYDPYKGEIRLNNVNINQIDKQTLRRHI
NYLPQQPYVFNGTILENLLLGAKEGTSQEDILWAVEMACIREDIEKMPLNYQTELTSDGAGISGGQRQRIALARALLTDA
PIMILDEATSSLDILTEKRIVDNLLSLDKTLIFIAHRLTIAERTEHIVVLDKGRIVEQGSHKELLDKQGFYEYLVNS

Nucleotide


Download         Length: 2154 bp        

>NTDB_id=577587 KQ224_RS06410 WP_174846491.1 1247707..1249860(-) (comA) [Streptococcus parasuis strain H35]
ATGAAATTTGGAAAACGTCATTATAGAGCACAAGTAGATACACGAGACTGTGGTGTGGCAGCGCTTGCTATGATCTTGGA
ATATTATCGTTCTCATCATTCTTTAGCAAGTTTGCGAGAAATGGCAAAGACAACTATGGAAGGCACGACAGCATTTGGTT
TAGTAAAGGTTGCTGAAGAGCTAGGGTTTGAGACGCGTGCGATTAAGGCAGATATGTCTTTGTTTTCGATGAGGGAAGCG
GTCTATCCTTTCATTGCCCATGTGGTAAAAGATGGCACGTTACTACATTATTATGTTGTCATTGGGGCAGATAAGAAATA
TATCTATATTGCAGACCCGGATCCATCAGTGAAATTAACAAAGTTATCCCATGAACAATTTGAAAAGGAGTGGACAGGAG
TTTCGCTATTCATGGCTCCCAAACCGGAATATCAACCTCATAAAGAGAAGAGTCATGGGTTACTTTCTTTCATTCCATTG
TTGACTAAACAAAAGGGATTGATTACAAATATTGTTCTCGCAACGCTCTTGGTTACTTTCATCAACATTGTGGGCTCCTA
TTATTTACAATCCATTATTGACACTTATGTTCCAAATCAGATGAAAACAACCTTAGGTGTCATTTCAGTCGGTTTGGTGG
TTGTTTATGCCCTGCAACAATTGTTATCTTATGCCCAAGAGTATTTATTAATCATTCTTGGGCAACGACTCTCTATTGAT
GTGATTTTGTCTTATATTAGACATGTTTTTCATCTACCAATGTCATTTTTTGCTACCCGGCGAACTGGGGAAATTGTTTC
ACGATTTACAGATGCCAATTCTATTATTGATGCTTTAGCTAGTACCATTCTATCAATATTTTTGGATGTATCTATTGTTG
TGGTTGTTTCGGTAGTGCTGTTTAGTCAGAATGTCTATCTTTTCTTTATTTCCTTGTTGGCATTGCCAATCTATACTCTA
ATCATTTTTGCGTTTATGAAACCATTTGAAAAGATGAATCAAGAAGTGATGGAAAGTAATGCAATTCTTTCTTCGTCTAT
TATTGAAGATATTAATGGTATTGAAACCATAAAATCATTGACAAGTGAGAAACAACGTTATCAGAAAATTGATAGAGAAT
TTGTAGATTATTTACAAAAATCATTTGCATACAACAAGGCCGAAGGGCAGCAAAAAGTGTTAAAGCGCTTGGCCCAACTC
GTATTAAATGTAGCAATTCTTTGGTTAGGAGCCTGTCTTGTTATGGATCACAAAATGACTTTGGGGCAGCTAATCACCTT
CAATACGTTATTGGTCTATTTCACGAATCCATTGGAAAATATAATCAATTTACAAACAAAACTACAGACAGCTCAAGTTG
CCAATACCCGCTTGAACGAGGTCTATTTGGTTGAATCGGAATTTGCTGAAAAGAAATCCGTGACGGACCTTTCGTTACTT
TCGGGGGATATTGAATGCAACAAAGTGCATTATAAATATGGCTATGGTAGGGATGTTTTGACAGATATTAATTTGAAAAT
TAAACGAGGGGAAAAGGTCTCCTTTGTTGGAGTTTCTGGTTCTGGGAAGACGACGTTGGCTAAAATGATGGTGGATTTTT
ATGACCCTTACAAGGGTGAGATTCGATTAAATAATGTCAACATTAATCAAATCGATAAGCAAACACTTCGTCGGCATATT
AATTATCTTCCACAGCAACCCTATGTTTTTAATGGGACAATTCTCGAAAATCTATTGCTAGGTGCAAAAGAGGGAACAAG
TCAAGAAGATATCTTGTGGGCTGTTGAAATGGCATGTATTAGAGAAGATATTGAAAAAATGCCACTGAATTACCAAACGG
AATTGACTTCTGATGGAGCTGGAATCTCCGGTGGACAACGGCAGCGAATTGCCTTGGCGCGTGCCCTTCTTACGGATGCC
CCTATTATGATTTTGGATGAGGCAACCAGTAGTCTGGATATTTTGACAGAGAAGCGTATTGTGGACAACCTATTGTCATT
GGACAAAACTCTAATTTTTATTGCACATCGGTTAACCATTGCAGAGCGTACTGAACATATTGTTGTGCTAGATAAGGGAA
GAATTGTAGAACAAGGGAGTCATAAGGAATTGTTAGACAAGCAAGGGTTCTATGAATATTTAGTAAATAGTTAG

Domains

Predicted by InterproScan.

ABC transporter transmembrane region (ABC_membrane)

(170-438)

Peptidase C39 family (Peptidase_C39)

(7-142)

ABC transporter (ABC_tran)

(500-650)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus pneumoniae Rx1

79.637

100

0.796
  comA Streptococcus pneumoniae D39

79.637

100

0.796
  comA Streptococcus pneumoniae R6

79.637

100

0.796
  comA Streptococcus mitis NCTC 12261

79.498

100

0.795
  comA Streptococcus pneumoniae TIGR4

79.358

100

0.794
  comA Streptococcus mitis SK321

79.358

100

0.794
  comA Streptococcus gordonii str. Challis substr. CH1

77.127

100

0.771
  comA/nlmT Streptococcus mutans UA159

63.738

100

0.637