Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   KRG72_RS04820 Genome accession   NZ_CP076703
Coordinates   957525..958199 (-) Length   224 a.a.
NCBI ID   WP_074563738.1    Uniprot ID   A0AAE8HJU5
Organism   Streptococcus equinus strain S1     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 952525..963199
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KRG72_RS04795 (KRG72_04800) deoC 952982..953647 (-) 666 WP_074560196.1 deoxyribose-phosphate aldolase -
  KRG72_RS04800 (KRG72_04805) - 954152..954742 (-) 591 WP_074867599.1 class I SAM-dependent methyltransferase -
  KRG72_RS04805 (KRG72_04810) coaA 954874..955794 (+) 921 WP_074964631.1 type I pantothenate kinase -
  KRG72_RS04810 (KRG72_04815) rpsT 955870..956121 (+) 252 WP_004231769.1 30S ribosomal protein S20 -
  KRG72_RS04815 (KRG72_04820) ciaH 956207..957535 (-) 1329 WP_258250093.1 cell wall metabolism sensor histidine kinase WalK Regulator
  KRG72_RS04820 (KRG72_04825) ciaR 957525..958199 (-) 675 WP_074563738.1 response regulator transcription factor Regulator
  KRG72_RS04825 (KRG72_04830) - 958366..960909 (-) 2544 WP_258250094.1 M1 family metallopeptidase -
  KRG72_RS04830 (KRG72_04835) phoU 961140..961793 (-) 654 WP_039696860.1 phosphate signaling complex protein PhoU -
  KRG72_RS04835 (KRG72_04840) pstB 961824..962582 (-) 759 WP_039696859.1 phosphate ABC transporter ATP-binding protein PstB -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25487.09 Da        Isoelectric Point: 4.3047

>NTDB_id=577462 KRG72_RS04820 WP_074563738.1 957525..958199(-) (ciaR) [Streptococcus equinus strain S1]
MIKILLVEDDLSLSNSIFDFLDDFADVMQVFDGEEGLYEAESGVYDLILLDLMLPEKDGFQVLKELREQGITTPVLIMTA
KESLDDKGHGFELGADDYLTKPFYLEELKMRIQALLKRSGKFNDNTLSYHELTADTSTNTTTVNGEKVELLGKEFDLLVY
FLQNQNVILPKSQIFDRIWGFDSDTTISVVEVYVSKIRKKLKGTNFAKNLQTLRSVGYILKDAE

Nucleotide


Download         Length: 675 bp        

>NTDB_id=577462 KRG72_RS04820 WP_074563738.1 957525..958199(-) (ciaR) [Streptococcus equinus strain S1]
ATGATTAAGATTTTATTAGTAGAAGATGATTTGAGTTTATCGAATTCAATCTTTGATTTTTTAGATGATTTTGCAGATGT
TATGCAAGTCTTTGATGGTGAAGAAGGGCTTTATGAGGCAGAAAGTGGTGTTTATGACCTCATTTTGCTTGATCTGATGT
TGCCAGAAAAAGATGGTTTCCAAGTTCTGAAAGAATTACGTGAACAAGGTATTACGACACCTGTCTTAATTATGACAGCC
AAAGAAAGCCTTGATGATAAAGGACACGGTTTTGAACTTGGTGCTGATGATTATTTGACAAAACCATTTTATCTTGAAGA
GTTGAAGATGCGTATTCAAGCGCTTTTGAAACGCTCTGGAAAATTCAATGATAATACTCTTTCTTACCACGAATTAACAG
CTGATACATCAACTAACACAACAACTGTTAACGGAGAAAAGGTGGAGTTACTAGGTAAAGAATTTGATTTATTGGTTTAT
TTCTTGCAAAACCAAAATGTTATTTTGCCAAAATCACAAATTTTTGACCGTATTTGGGGATTTGATAGCGATACTACAAT
TTCAGTTGTTGAAGTTTATGTTTCTAAGATTCGCAAAAAATTAAAAGGAACAAATTTTGCTAAAAATCTACAAACACTTC
GTAGTGTAGGGTATATTCTAAAAGATGCTGAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus mutans UA159

92.825

99.554

0.924
  ciaR Streptococcus pneumoniae Rx1

87.946

100

0.879
  ciaR Streptococcus pneumoniae D39

87.946

100

0.879
  ciaR Streptococcus pneumoniae R6

87.946

100

0.879
  ciaR Streptococcus pneumoniae TIGR4

87.946

100

0.879
  covR Lactococcus lactis subsp. lactis strain DGCC12653

38.326

100

0.388
  vicR Streptococcus mutans UA159

34.764

100

0.362