Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   KPA27_RS07375 Genome accession   NZ_CP076517
Coordinates   1477446..1478150 (-) Length   234 a.a.
NCBI ID   WP_002935840.1    Uniprot ID   A0A0M9FML3
Organism   Streptococcus suis strain 39565     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1472446..1483150
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KPA27_RS07360 (KPA27_07360) vga(F) 1473416..1474801 (-) 1386 WP_202847633.1 ABC-F type ribosomal protection protein Vga(F) -
  KPA27_RS07365 (KPA27_07365) vicX 1475294..1476097 (-) 804 WP_024407014.1 MBL fold metallo-hydrolase Regulator
  KPA27_RS07370 (KPA27_07370) micB 1476104..1477453 (-) 1350 WP_029180103.1 cell wall metabolism sensor histidine kinase VicK Regulator
  KPA27_RS07375 (KPA27_07375) micA 1477446..1478150 (-) 705 WP_002935840.1 response regulator YycF Regulator
  KPA27_RS07380 (KPA27_07380) - 1478344..1479105 (+) 762 WP_002935839.1 amino acid ABC transporter ATP-binding protein -
  KPA27_RS07385 (KPA27_07385) - 1479116..1479955 (+) 840 WP_202847632.1 transporter substrate-binding domain-containing protein -
  KPA27_RS07390 (KPA27_07390) - 1479970..1480668 (+) 699 WP_013730248.1 amino acid ABC transporter permease -
  KPA27_RS07395 (KPA27_07395) - 1480683..1481342 (+) 660 WP_014637676.1 amino acid ABC transporter permease -

Sequence

Protein


Download         Length: 234 a.a.        Molecular weight: 26751.75 Da        Isoelectric Point: 4.8957

>NTDB_id=576124 KPA27_RS07375 WP_002935840.1 1477446..1478150(-) (micA) [Streptococcus suis strain 39565]
MKKILIVDDEKPISDIIKFNMTREGYEVVTAFDGREALEVFEAEFPDIVILDLMLPELDGLEVARTIRKTSNVPILMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELQARVKALLRRSELAETQTNIESTGTPELVIGDLVILPDAFVAKKHGKELELT
HREFELLHHLAKHLGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDAPSRPEYILTRRGVGYFIKGND

Nucleotide


Download         Length: 705 bp        

>NTDB_id=576124 KPA27_RS07375 WP_002935840.1 1477446..1478150(-) (micA) [Streptococcus suis strain 39565]
ATGAAAAAAATATTAATTGTAGATGATGAAAAACCAATCTCAGATATTATTAAGTTTAATATGACTCGTGAGGGGTATGA
AGTTGTGACAGCTTTTGATGGACGTGAAGCCTTGGAAGTATTTGAGGCTGAGTTTCCTGACATTGTCATTTTGGACTTGA
TGCTGCCAGAATTGGACGGACTAGAGGTTGCTCGAACGATTCGTAAGACCAGCAATGTTCCAATCTTGATGTTATCTGCT
AAAGATAGCGAATTTGATAAGGTTATCGGGCTTGAAATCGGGGCGGATGATTATGTGACCAAGCCCTTCTCTAATCGCGA
ATTGCAGGCGCGTGTTAAGGCTCTTCTTCGTCGTAGTGAATTGGCAGAGACGCAGACAAATATTGAGTCAACAGGAACTC
CAGAGTTGGTGATTGGCGATTTGGTCATTCTGCCTGATGCGTTTGTCGCTAAGAAGCATGGTAAAGAGCTGGAGCTGACC
CATCGTGAGTTTGAATTGCTCCACCATCTGGCCAAACACTTAGGTCAGGTTATGACTCGAGAACATCTATTGGAAACAGT
TTGGGGTTATGATTACTTTGGTGATGTCCGCACGGTGGATGTAACGATTCGTCGTCTGCGTGAGAAAATTGAAGATGCAC
CAAGCAGACCAGAATACATTCTTACTCGTCGCGGAGTGGGATATTTTATAAAAGGAAATGATTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-229)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0M9FML3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

81.545

99.573

0.812
  vicR Streptococcus mutans UA159

80

100

0.803
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.783

98.291

0.44
  covR Streptococcus salivarius strain HSISS4

43.723

98.718

0.432
  scnR Streptococcus mutans UA159

38.095

98.718

0.376