Detailed information    

insolico Bioinformatically predicted

Overview

Name   micB   Type   Regulator
Locus tag   KPA27_RS07370 Genome accession   NZ_CP076517
Coordinates   1476104..1477453 (-) Length   449 a.a.
NCBI ID   WP_029180103.1    Uniprot ID   -
Organism   Streptococcus suis strain 39565     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1471104..1482453
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KPA27_RS07355 (KPA27_07355) pbp2b 1471255..1473324 (-) 2070 WP_014637681.1 penicillin-binding protein PBP2B -
  KPA27_RS07360 (KPA27_07360) vga(F) 1473416..1474801 (-) 1386 WP_202847633.1 ABC-F type ribosomal protection protein Vga(F) -
  KPA27_RS07365 (KPA27_07365) vicX 1475294..1476097 (-) 804 WP_024407014.1 MBL fold metallo-hydrolase Regulator
  KPA27_RS07370 (KPA27_07370) micB 1476104..1477453 (-) 1350 WP_029180103.1 cell wall metabolism sensor histidine kinase VicK Regulator
  KPA27_RS07375 (KPA27_07375) micA 1477446..1478150 (-) 705 WP_002935840.1 response regulator YycF Regulator
  KPA27_RS07380 (KPA27_07380) - 1478344..1479105 (+) 762 WP_002935839.1 amino acid ABC transporter ATP-binding protein -
  KPA27_RS07385 (KPA27_07385) - 1479116..1479955 (+) 840 WP_202847632.1 transporter substrate-binding domain-containing protein -
  KPA27_RS07390 (KPA27_07390) - 1479970..1480668 (+) 699 WP_013730248.1 amino acid ABC transporter permease -
  KPA27_RS07395 (KPA27_07395) - 1480683..1481342 (+) 660 WP_014637676.1 amino acid ABC transporter permease -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 51065.11 Da        Isoelectric Point: 4.5202

>NTDB_id=576123 KPA27_RS07370 WP_029180103.1 1476104..1477453(-) (micB) [Streptococcus suis strain 39565]
MINQLRYLMTTAEFWFVVILIGFLIALTVLLIENYRDNKQIKQLNQKVNALIEGNYADVLDMRGSPEITDMANSLNDLSE
VIRLTHDNLEQEKTRLTSILSYMSDGVIATDRIGRIIMINDMAQKQLGLSNPKQEQYHLLEVLDLSDRYTLRDLLAQTPE
IVIDHTNENEEFLTLRANFATIRSESGLISGLVVVLHDMTEQAKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALT
ESVAPSFVKVSLDETNRMMRMITDLLSLSRIDNQVGQIDVELINFTAFVTFILNRFDQMKNTDSDKVYTIVRDYQISPIW
VEIDTDKMTQVLDNILNNAIKYSPDGGTITFSMKTTDSQLIVSVSDEGLGIPKADLPRIFDRFYRVDKARSRAQGGTGLG
LAIAKEIVKQHKGFIWAKSEYGHGSTFTIVLPYSKDIALDEWDDSDEEE

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=576123 KPA27_RS07370 WP_029180103.1 1476104..1477453(-) (micB) [Streptococcus suis strain 39565]
ATGATTAATCAATTACGTTATTTAATGACCACGGCAGAATTTTGGTTTGTTGTCATTTTGATTGGCTTTCTAATTGCTCT
AACGGTCCTTTTGATTGAAAACTATCGGGATAATAAGCAAATTAAACAACTCAATCAAAAAGTCAATGCCTTAATTGAGG
GGAATTATGCAGATGTGTTAGACATGAGGGGAAGTCCTGAAATCACAGATATGGCTAATTCCCTCAATGATTTGTCCGAG
GTTATCCGCTTAACTCATGATAATTTAGAACAAGAAAAGACGCGTCTGACTTCCATCCTGTCCTATATGAGTGACGGTGT
TATTGCTACAGACCGTATCGGACGGATCATCATGATTAACGATATGGCCCAGAAACAGTTGGGGTTATCTAACCCAAAGC
AGGAGCAGTATCACCTGCTCGAGGTTTTAGATTTATCAGACCGTTATACATTGAGAGATTTGTTGGCTCAGACACCTGAG
ATTGTGATTGATCACACCAATGAAAACGAAGAATTTTTGACTTTACGCGCTAATTTTGCCACGATTCGTAGTGAGAGTGG
TCTGATTTCTGGCTTGGTTGTCGTCTTGCATGATATGACCGAGCAGGCCAAGGAAGAGCGGGAACGTAGGCTGTTTGTGT
CAAATGTGAGTCATGAATTGCGTACGCCATTGACTTCCGTTAAATCCTATCTAGAGGCTCTGGATGAGGGAGCGCTGACG
GAGTCTGTTGCACCGAGTTTTGTCAAGGTATCCTTAGATGAGACCAACCGCATGATGCGGATGATTACAGACCTCCTAAG
CTTATCGCGTATTGATAATCAAGTTGGTCAGATAGATGTTGAACTGATAAACTTTACTGCTTTTGTGACCTTTATTCTTA
ACCGTTTTGACCAAATGAAAAATACTGATTCTGATAAGGTCTATACGATTGTTCGTGACTATCAAATCAGTCCTATTTGG
GTTGAGATTGATACAGATAAGATGACTCAGGTTTTAGATAATATCTTAAATAATGCCATTAAATATTCGCCAGATGGCGG
GACAATTACCTTCAGCATGAAGACCACAGATAGCCAGTTGATTGTATCCGTATCAGACGAAGGTCTGGGGATTCCGAAAG
CAGATTTACCTAGAATTTTTGACCGATTTTATCGTGTAGACAAGGCACGATCTCGTGCCCAAGGTGGTACAGGTCTTGGT
TTAGCTATTGCAAAAGAAATCGTAAAACAGCATAAGGGTTTTATCTGGGCTAAAAGCGAATATGGTCATGGCTCAACGTT
TACAATTGTCTTGCCGTACAGCAAGGACATCGCACTAGATGAGTGGGATGATTCAGATGAGGAAGAATAG

Domains

Predicted by InterproScan.

PAS fold (PAS)

(96-199)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-434)

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micB Streptococcus pneumoniae Cp1015

70.183

97.105

0.682
  vicK Streptococcus mutans UA159

70.72

89.755

0.635