Detailed information NTG0568241

Bioinformatically predicted

Overview

• Name: comEA
• Type: Machinery gene
• Locus tag: KIP81_RS03260
• Genome accession: NZ_CP075172
• Coordinates: 619856..620536 (+)
• Length: 226 a.a.
• NCBI ID: WP_243603169.1
• Uniprot ID: -
• Organism: Streptococcus equinus strain SheepZ001
• Function: dsDNA binding to the cell surface (predicted from homology) DNA binding and uptake

Genomic Context

Location: 614856..625536

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KIP81_RS03230 (KIP81_03235)	-	614874..616073 (+)	1200	WP_243603165.1	MFS transporter	-
KIP81_RS03235 (KIP81_03240)	-	616104..616970 (+)	867	WP_243603166.1	helix-turn-helix transcriptional regulator	-
KIP81_RS03240 (KIP81_03245)	-	616980..617870 (+)	891	WP_243603167.1	ROK family protein	-
KIP81_RS03245 (KIP81_03250)	-	617885..618160 (-)	276	WP_024344272.1	GIY-YIG nuclease family protein	-
KIP81_RS03250 (KIP81_03255)	-	618135..618896 (-)	762	WP_243603168.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
KIP81_RS03255 (KIP81_03260)	-	619015..619761 (+)	747	WP_024344274.1	1-acyl-sn-glycerol-3-phosphate acyltransferase	-
KIP81_RS03260 (KIP81_03265)	comEA	619856..620536 (+)	681	WP_243603169.1	helix-hairpin-helix domain-containing protein	Machinery gene
KIP81_RS03265 (KIP81_03270)	comEC/celB	620529..622748 (+)	2220	WP_243603170.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
KIP81_RS03270 (KIP81_03275)	-	622755..623609 (-)	855	WP_243603369.1	Rgg/GadR/MutR family transcriptional regulator	-
KIP81_RS03275 (KIP81_03280)	-	623776..624978 (+)	1203	WP_243603171.1	ATP-grasp domain-containing protein	-

Sequence

Protein

• Length: 226 a.a.
• Molecular weight: 24159.10 Da
• Isoelectric Point: 4.5485

>NTDB_id=568241 KIP81_RS03260 WP_243603169.1 619856..620536(+) (comEA) [Streptococcus equinus strain SheepZ001]
MIEEMKEKILEHKTVASVLGTVLVMLVIFFAWSSMESHKAEVQNDLPALSTSFSTSRAETSQPKTVASASKSESDKIFVD
IKGAVRKEGVYELISGSRVTDVVKLAGGFTDDADKKSVNLAEKVADEAVIYVARVGEEVTPASTPSQAKNTATSGAQQDA
DSAQINLNTATLEELQTISGIGVKRAQDIIDYRDNNGGFSSVDDLKNVSGIGEKTLEKLKAEVTVD

Nucleotide

• Length: 681 bp

>NTDB_id=568241 KIP81_RS03260 WP_243603169.1 619856..620536(+) (comEA) [Streptococcus equinus strain SheepZ001]
ATGATTGAAGAGATGAAAGAAAAAATTTTAGAGCATAAAACTGTGGCATCAGTTTTGGGGACAGTTCTTGTTATGCTAGT
GATTTTTTTTGCTTGGTCTAGTATGGAAAGCCACAAAGCTGAAGTGCAAAATGATTTACCAGCATTGAGCACTAGCTTTT
CAACAAGTAGGGCAGAAACATCTCAGCCAAAAACAGTAGCATCTGCTTCAAAGTCGGAATCAGATAAGATTTTCGTTGAT
ATTAAAGGTGCCGTCAGAAAAGAAGGCGTTTATGAATTGATATCAGGTAGTCGTGTGACAGATGTGGTCAAATTAGCTGG
CGGCTTTACAGATGATGCAGATAAGAAATCTGTTAATTTAGCTGAAAAAGTAGCGGACGAAGCAGTGATTTACGTGGCAA
GAGTTGGTGAAGAGGTCACACCAGCAAGCACTCCGTCTCAAGCTAAAAATACAGCAACAAGTGGAGCGCAGCAAGATGCG
GACTCAGCACAAATCAATCTTAATACTGCGACTTTAGAAGAACTTCAGACGATTTCTGGCATCGGTGTCAAACGTGCTCA
AGACATTATCGATTATCGTGATAACAACGGTGGATTTTCGTCAGTTGATGATTTGAAAAATGTGTCAGGTATTGGTGAGA
AGACCTTAGAAAAACTAAAAGCTGAGGTGACAGTTGATTAA

Domains

Predicted by InterproScan.

• Helix-hairpin-helix motif (HHH_3) (163-224)

• SLBB domain (SLBB) (79-132)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEA	Streptococcus thermophilus LMD-9	46.581	100	0.482
comEA/celA/cilE	Streptococcus mitis SK321	44.889	99.558	0.447
comEA/celA/cilE	Streptococcus mitis NCTC 12261	44.889	99.558	0.447
comEA/celA/cilE	Streptococcus pneumoniae TIGR4	44.493	100	0.447
comEA/celA/cilE	Streptococcus pneumoniae Rx1	43.556	99.558	0.434
comEA/celA/cilE	Streptococcus pneumoniae D39	43.556	99.558	0.434
comEA/celA/cilE	Streptococcus pneumoniae R6	43.556	99.558	0.434
comEA	Latilactobacillus sakei subsp. sakei 23K	39.462	98.673	0.389