Detailed information NTG0568218

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: KIP81_RS00355
• Genome accession: NZ_CP075172
• Coordinates: 51941..52852 (+)
• Length: 303 a.a.
• NCBI ID: WP_074630203.1
• Uniprot ID: -
• Organism: Streptococcus equinus strain SheepZ001
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 46941..57852

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KIP81_RS00330 (KIP81_00330)	-	48141..48590 (+)	450	WP_243602928.1	DUF523 domain-containing protein	-
KIP81_RS00335 (KIP81_00335)	purE	48590..49078 (+)	489	WP_021141395.1	5-(carboxyamino)imidazole ribonucleotide mutase	-
KIP81_RS00340 (KIP81_00340)	purK	49065..50156 (+)	1092	WP_243602929.1	5-(carboxyamino)imidazole ribonucleotide synthase	-
KIP81_RS00345 (KIP81_00345)	-	50178..50402 (+)	225	WP_243602930.1	phosphoribosylaminoimidazole carboxylase	-
KIP81_RS00350 (KIP81_00350)	purB	50493..51791 (+)	1299	WP_024344772.1	adenylosuccinate lyase	-
KIP81_RS00355 (KIP81_00355)	comR	51941..52852 (+)	912	WP_074630203.1	XRE family transcriptional regulator	Regulator
KIP81_RS00360 (KIP81_00360)	ruvB	53023..54021 (+)	999	WP_021141399.1	Holliday junction branch migration DNA helicase RuvB	-
KIP81_RS00365 (KIP81_00365)	-	54231..54662 (+)	432	WP_033152105.1	low molecular weight protein-tyrosine-phosphatase	-
KIP81_RS00370 (KIP81_00370)	-	54679..55059 (+)	381	WP_243602931.1	hypothetical protein	-
KIP81_RS00375 (KIP81_00375)	-	55056..56849 (+)	1794	WP_243602932.1	acyltransferase family protein	-

Sequence

Protein

• Length: 303 a.a.
• Molecular weight: 35503.88 Da
• Isoelectric Point: 4.7561

>NTDB_id=568218 KIP81_RS00355 WP_074630203.1 51941..52852(+) (comR) [Streptococcus equinus strain SheepZ001]
MEVKKFGNKIRILREKKGISREELCGDETELSVRQLARIELNQSIPNLSKAQFIANRLGVKLGTLTDGDSLELPKRYKEL
KYLILRTPTYKDEKRVNLRDSYFDEIYSDFYDDLPEEEQLIVECMRSKADVFLTDNSNLATKLLEDYFYQTKLKSHYSIN
DLIIIDLYMVCANASNYEYFMFDKNEFIGIAKNLLEQENHFSLAEIFVLNNILFGSLSLLVDLKMWDEVELTLDVLKGIM
AKIQDFHKKPVLNMIEWKYILERFGQTEKAQKLYEEAVLYANLIGDVYLANKITEEWIKDTTA

Nucleotide

• Length: 912 bp

>NTDB_id=568218 KIP81_RS00355 WP_074630203.1 51941..52852(+) (comR) [Streptococcus equinus strain SheepZ001]
ATGGAAGTGAAAAAATTTGGGAACAAAATTCGTATTTTGCGGGAGAAAAAGGGAATCTCACGCGAAGAACTCTGTGGGGA
CGAGACCGAATTATCCGTACGACAACTAGCACGAATTGAGCTAAATCAATCGATACCTAACCTAAGTAAAGCCCAATTCA
TTGCTAATCGCCTTGGCGTAAAACTCGGAACCCTGACAGACGGTGATAGCTTAGAATTACCAAAGCGGTATAAAGAGCTG
AAGTATTTAATTTTGCGTACGCCAACGTATAAAGATGAAAAACGTGTGAATTTAAGAGATTCTTATTTTGATGAGATTTA
CTCTGACTTTTACGATGACCTTCCTGAGGAGGAGCAATTAATCGTGGAGTGCATGCGCTCAAAAGCAGATGTCTTTTTAA
CTGATAATAGTAATTTAGCCACAAAGTTGTTAGAAGATTATTTTTATCAAACAAAATTAAAATCGCATTATTCGATTAAT
GATTTAATCATAATTGATTTATATATGGTTTGTGCAAATGCTTCAAATTATGAATATTTTATGTTTGATAAAAATGAATT
TATTGGTATAGCTAAGAATCTATTAGAACAAGAAAATCACTTTTCACTAGCAGAAATTTTTGTCTTAAATAATATTTTAT
TTGGTAGTTTGAGCTTGTTGGTTGATTTAAAAATGTGGGACGAAGTGGAATTGACTTTAGATGTTTTAAAAGGAATTATG
GCTAAAATTCAAGATTTTCATAAGAAGCCAGTTTTGAATATGATTGAGTGGAAGTATATTTTGGAACGTTTTGGTCAAAC
AGAAAAGGCTCAAAAATTATATGAAGAGGCAGTGTTATATGCAAATTTGATAGGTGATGTTTATTTAGCTAATAAAATAA
CAGAAGAATGGATAAAAGATACAACAGCATGA

Domains

Predicted by InterproScan.

• Helix-turn-helix (HTH_3) (10-63)

• ComR tetratricopeptide (ComR_TPR) (74-297)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus infantarius subsp. infantarius ATCC BAA-102	51.546	96.04	0.495
comR	Streptococcus pyogenes MGAS8232	47.176	99.34	0.469
comR	Streptococcus mutans UA159	46.823	98.68	0.462
comR	Streptococcus pyogenes MGAS315	46.644	98.35	0.459
comR	Streptococcus suis P1/7	39.394	98.02	0.386
comR	Streptococcus suis 05ZYH33	39.394	98.02	0.386
comR	Streptococcus suis D9	37.097	100	0.38