Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEC/celB   Type   Machinery gene
Locus tag   SITYG_RS05465 Genome accession   NZ_AP014880
Coordinates   1077818..1080052 (-) Length   744 a.a.
NCBI ID   WP_096362892.1    Uniprot ID   -
Organism   Streptococcus intermedius strain TYG1620     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1072818..1085052
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SITYG_RS05440 (SITYG_10620) - 1073140..1074414 (-) 1275 WP_096362890.1 dihydroorotase -
  SITYG_RS05445 (SITYG_10630) mutX 1074426..1074896 (-) 471 WP_020998594.1 NUDIX hydrolase Machinery gene
  SITYG_RS05450 (SITYG_10640) - 1074923..1075576 (-) 654 WP_009568677.1 uracil-DNA glycosylase -
  SITYG_RS05455 (SITYG_10650) - 1075601..1076587 (-) 987 WP_096362891.1 Gfo/Idh/MocA family protein -
  SITYG_RS05460 (SITYG_10660) - 1077027..1077740 (-) 714 WP_048786492.1 DUF805 domain-containing protein -
  SITYG_RS05465 (SITYG_10670) comEC/celB 1077818..1080052 (-) 2235 WP_096362892.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  SITYG_RS05470 (SITYG_10680) comEA/celA/cilE 1080036..1080740 (-) 705 WP_096362893.1 helix-hairpin-helix domain-containing protein Machinery gene
  SITYG_RS05475 (SITYG_10700) smpB 1080908..1081375 (-) 468 WP_096362894.1 SsrA-binding protein SmpB -
  SITYG_RS05480 (SITYG_10710) rnr 1081338..1083677 (-) 2340 WP_096362895.1 ribonuclease R -
  SITYG_RS05485 (SITYG_10720) secG 1083768..1084001 (-) 234 WP_003024744.1 preprotein translocase subunit SecG -

Sequence

Protein


Download         Length: 744 a.a.        Molecular weight: 85265.20 Da        Isoelectric Point: 10.0941

>NTDB_id=56528 SITYG_RS05465 WP_096362892.1 1077818..1080052(-) (comEC/celB) [Streptococcus intermedius strain TYG1620]
MSQWIKIFPIKPIYIAFLLVWLYFAIYQSNWLAGVGLIFLLIRLSRIYSLKEWFTTFMILACFAVFFLVRRELANRKIKV
EAPPVRQVAVLPDTIKVNGDSLSFRGKAKGQTYQIYYKLKSKEEKLAFQNLSSLVTLTVEGEFESPEKQRNFSGFDYQAY
LKTQGIYRILKVDQILSSQDRVSLQPFEWLSSWRRKALVFIKRNFPNPMSNYMTGLLFGALDTDFGEMNNLYSSLGIIHL
FALSGMQVGFFMEGFRKSLLRLGLTQEIVHKCQYPFSFFYAGMTGFSVSVVRSLIQKLLSQHGITKLDNFALTIMVLSLI
MPSFLLTAGGVLSCAYAFIISVLDFKGLTPYKKIIIESIVISLGILPILIFYFGEFQPWSILLTFVFSLIFDIVMLPGLT
IIFLVSPFIKLTQVNFLFECLESSIRWLASMFSRPVVLGKPNPLLLIAMLLVLAILYDIRQNKKWLIFLSLFLSLLFFVA
KFPLQNEITMIDVGKGDSIFMRDWRGSTVLIDVGGREEIRKKESWQERISSSNAERTLIPYLKSRGVDTIDTLVLTNPNS
DYAGDVLEVAKKFSIKKIFISRSSLNDADFLNKLKETKAFVHVVKQGDKLPIFDHHLQVLSGTNKNDQSLVLYGQFFRTR
FLFMSNLTEEDEVKLMQLYPKLKTDVLKVGQHGSQNSSSSKFLQQVRPVIALISTGENNSSKSLSQETIERFDRLNTKIY
RTDKQGAIKFSGWTTWQLETVQQP

Nucleotide


Download         Length: 2235 bp        

>NTDB_id=56528 SITYG_RS05465 WP_096362892.1 1077818..1080052(-) (comEC/celB) [Streptococcus intermedius strain TYG1620]
ATGTCACAGTGGATTAAGATATTTCCGATCAAACCAATTTATATTGCTTTCTTACTTGTCTGGTTATATTTTGCAATCTA
TCAAAGCAATTGGTTGGCAGGAGTGGGATTGATCTTTCTGTTAATTCGTCTTTCTCGCATATATTCGCTAAAAGAATGGT
TTACAACTTTCATGATTCTCGCTTGTTTTGCTGTTTTTTTCCTTGTTCGTAGGGAACTGGCGAATCGGAAGATAAAAGTA
GAAGCTCCTCCTGTAAGACAAGTTGCGGTTTTACCTGATACAATTAAGGTAAATGGAGATTCGCTTTCTTTTCGTGGTAA
AGCAAAAGGACAGACATATCAAATTTACTACAAATTGAAATCAAAAGAAGAAAAGTTGGCTTTTCAAAATCTATCCAGTC
TTGTCACATTAACTGTTGAGGGGGAATTTGAATCTCCTGAAAAGCAGCGCAATTTTTCTGGTTTTGATTATCAAGCCTAT
CTAAAAACACAAGGGATTTATCGAATTTTAAAGGTGGATCAAATTTTGTCTAGCCAAGATAGGGTTAGCCTCCAACCGTT
TGAGTGGCTGTCTAGCTGGCGAAGAAAAGCATTGGTTTTCATTAAGAGAAATTTCCCGAATCCAATGAGCAATTATATGA
CAGGACTTTTGTTCGGAGCTTTGGATACAGATTTTGGTGAAATGAATAACCTTTATTCGAGCTTGGGAATTATTCATTTA
TTTGCATTGTCTGGTATGCAAGTTGGTTTTTTTATGGAAGGGTTTCGTAAGTCACTGTTGAGATTGGGGCTTACGCAGGA
AATAGTTCATAAGTGTCAATATCCATTTTCTTTTTTTTATGCTGGAATGACAGGTTTTTCAGTATCCGTTGTACGGAGTT
TAATCCAGAAATTATTGTCACAACACGGCATTACTAAGTTAGATAATTTTGCTTTAACAATAATGGTGTTGTCCTTGATT
ATGCCCTCCTTTCTTTTAACAGCAGGAGGAGTACTTTCTTGTGCGTATGCTTTTATCATTAGCGTTTTAGATTTTAAAGG
CCTGACTCCTTATAAAAAGATTATTATAGAGAGTATTGTCATTTCGCTTGGCATTTTACCAATTTTAATCTTTTATTTCG
GAGAATTTCAGCCCTGGTCTATTTTATTGACATTTGTTTTTTCGTTGATTTTCGATATAGTGATGTTACCGGGGCTAACG
ATAATTTTTCTTGTTTCCCCTTTCATAAAACTCACTCAAGTTAATTTTCTATTTGAATGCTTAGAAAGTAGCATTCGCTG
GTTAGCAAGTATGTTTAGCAGACCAGTCGTTCTTGGCAAACCTAATCCACTTTTGCTAATCGCTATGTTGCTTGTATTAG
CTATCTTGTATGATATTCGGCAAAATAAAAAATGGCTGATATTTCTTAGTCTGTTTCTTTCATTACTCTTTTTTGTAGCT
AAATTTCCTTTACAAAATGAAATCACAATGATTGATGTCGGGAAGGGAGATAGTATTTTTATGCGAGACTGGAGAGGGAG
CACTGTATTGATTGATGTTGGCGGACGTGAAGAAATTAGAAAAAAAGAAAGTTGGCAAGAACGTATAAGTAGTTCAAACG
CAGAGAGAACGCTGATTCCATATCTTAAAAGTCGTGGTGTAGATACGATTGATACTTTAGTCTTAACAAATCCAAATTCA
GATTATGCAGGAGATGTATTAGAAGTTGCTAAAAAGTTTTCGATAAAGAAAATTTTTATTTCCAGAAGTAGTTTGAATGA
TGCAGACTTTTTAAATAAATTAAAGGAGACAAAGGCATTTGTTCATGTCGTAAAACAAGGAGACAAACTTCCTATTTTTG
ATCATCACTTGCAAGTTCTTTCTGGTACGAATAAGAATGATCAATCGCTAGTTTTATATGGTCAATTTTTTCGTACAAGG
TTTTTATTTATGAGCAATTTAACAGAAGAGGATGAAGTAAAGCTAATGCAACTTTATCCAAAACTAAAAACAGATGTCTT
GAAGGTTGGGCAACATGGATCCCAAAATTCATCAAGTTCTAAGTTCTTACAGCAAGTAAGACCAGTGATTGCCCTCATCT
CTACTGGGGAAAACAATTCATCCAAATCGCTAAGTCAAGAAACAATTGAGCGATTCGATCGGTTAAATACAAAGATCTAT
CGAACAGATAAACAGGGAGCTATTAAGTTTTCGGGTTGGACAACATGGCAATTAGAAACTGTTCAGCAACCATAG

Domains

Predicted by InterProScan.

Domain of unknown function (DUF4131) (DUF4131)

(31-175)

Competence protein (Competence)

(216-461)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEC/celB Streptococcus mitis SK321

55.689

100

0.559
  comEC/celB Streptococcus mitis NCTC 12261

55.496

100

0.556
  comEC/celB Streptococcus pneumoniae TIGR4

54.485

100

0.547
  comEC/celB Streptococcus pneumoniae Rx1

53.949

100

0.542
  comEC/celB Streptococcus pneumoniae D39

53.949

100

0.542
  comEC/celB Streptococcus pneumoniae R6

53.949

100

0.542
  comEC Lactococcus lactis subsp. cremoris KW2

46.03

99.866

0.46

Multiple sequence alignment