Detailed information NTG0558789

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: KCL43_RS07855
• Genome accession: NZ_CP073275
• Coordinates: 1661142..1663298 (+)
• Length: 718 a.a.
• NCBI ID: WP_165623393.1
• Uniprot ID: -
• Organism: Streptococcus equi subsp. zooepidemicus strain IN-6992
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 1656142..1668298

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KCL43_RS07810 (KCL43_07810)	-	1656413..1656994 (-)	582	WP_043053340.1	GNAT family N-acetyltransferase	-
KCL43_RS07815 (KCL43_07815)	-	1657238..1657663 (-)	426	WP_228294449.1	bacteriocin immunity protein	-
KCL43_RS07820 (KCL43_07820)	-	1657683..1657919 (-)	237	WP_165623394.1	bacteriocin class II family protein	-
KCL43_RS07825 (KCL43_07825)	-	1658450..1658653 (-)	204	WP_012679939.1	bacteriocin	-
KCL43_RS07830 (KCL43_07830)	-	1658670..1658924 (-)	255	WP_043053342.1	Blp family class II bacteriocin	-
KCL43_RS07835 (KCL43_07835)	-	1659661..1659960 (-)	300	WP_014623336.1	bacteriocin immunity protein	-
KCL43_RS07840 (KCL43_07840)	-	1659967..1660215 (-)	249	WP_014623337.1	garvicin Q family class II bacteriocin	-
KCL43_RS07845 (KCL43_07845)	-	1660369..1660665 (-)	297	WP_012516111.1	bacteriocin immunity protein	-
KCL43_RS07850 (KCL43_07850)	-	1660665..1660883 (-)	219	WP_021321057.1	leucocin A/sakacin P family class II bacteriocin	-
KCL43_RS07855 (KCL43_07855)	comA/nlmT	1661142..1663298 (+)	2157	WP_165623393.1	peptide cleavage/export ABC transporter	Regulator
KCL43_RS07860 (KCL43_07860)	-	1663309..1664666 (+)	1358	Protein_1535	bacteriocin secretion accessory protein	-
KCL43_RS07865 (KCL43_07865)	-	1664766..1664900 (+)	135	WP_043030066.1	ComC/BlpC family leader-containing pheromone/bacteriocin	-
KCL43_RS07870 (KCL43_07870)	-	1665019..1666353 (-)	1335	WP_165623392.1	sensor histidine kinase	-
KCL43_RS07875 (KCL43_07875)	comE/blpR	1666353..1667102 (-)	750	WP_042671079.1	LytR/AlgR family response regulator transcription factor	Regulator
KCL43_RS07880 (KCL43_07880)	-	1667729..1667932 (-)	204	WP_012516120.1	TmhB bacteriocin enhancer peptide	-
KCL43_RS07885 (KCL43_07885)	-	1667949..1668206 (-)	258	WP_038674051.1	Blp family class II bacteriocin	-

Sequence

Protein

• Length: 718 a.a.
• Molecular weight: 80589.75 Da
• Isoelectric Point: 7.4612

>NTDB_id=558789 KCL43_RS07855 WP_165623393.1 1661142..1663298(+) (comA/nlmT) [Streptococcus equi subsp. zooepidemicus strain IN-6992]
MTLFYKRTFVPQIDARDCGVAALASIARYYGSDYSLAYLRELAKTNKEGTTALGIVMAAKEMGFETRPIQADMTLFDMAD
VPYPLIVHVNKEGKLQHYYVVYKSKKDYLIIGDPDPMVKVTKMSKERFASEWTGVTICLAPKPNYKPHKDQKNGLLGFFP
LIFKQRALIFYIVLASVLVTVINISGSYYLQGILDEYIPNQLKSTLGIVSIGLIITYILQQLMSFSRDYLLTVLSQRLTI
DVILSYIRHIFELPMSFFATRRTGEVTSRFTDANSIIDALASTILSLFLDLSILAIVGSVLLVQNSRLFLLSLISIPVYT
IIICAFIKPFEQMNHDVMQSNAMLSSAIIEDINGIETIKSLTSEENRYQKIDSDFVDYLDKSFKLSKYTILQATLKQGAQ
LILNIIILWFGAQLVINGKISIGQLITFNTLLAYFTTPLENIINLQTKLQAAKVANNRLNEVYLVESEFKASQALYDLSL
LQGDIQFEAVSYRYGFGKDTLSDITLTIKQGAKVTLVGVSGSGKTTLAKMLVNFFEPYKGRITINQNDLKTIDKKNLRQY
INYLPQQAYIFNGSILENLTLGAKQGISQEDILNACEIADIRHDIEQMPMGYQTELSDGAGLSGGQKQRIALARALLTQA
PILVLDEATSGLDILTEKKIIDRLMNMTDKTIIFVAHRLSIAERTDQVVVLNQGQIIETGSHQELMKQGGFYYHLFSE

Nucleotide

• Length: 2157 bp

>NTDB_id=558789 KCL43_RS07855 WP_165623393.1 1661142..1663298(+) (comA/nlmT) [Streptococcus equi subsp. zooepidemicus strain IN-6992]
ATGACACTTTTTTATAAAAGAACCTTTGTACCACAAATAGATGCCAGAGATTGTGGCGTAGCTGCTCTAGCCTCAATCGC
AAGGTATTATGGTTCAGATTATTCATTAGCTTATTTGAGAGAATTAGCAAAGACCAATAAGGAAGGGACAACAGCCCTCG
GTATTGTCATGGCTGCTAAGGAAATGGGGTTTGAAACCAGACCTATTCAAGCGGATATGACCCTCTTTGACATGGCAGAC
GTGCCCTATCCATTGATCGTCCATGTCAATAAAGAAGGAAAGCTACAGCACTACTATGTGGTCTACAAATCTAAAAAAGA
CTATCTTATCATTGGTGATCCCGATCCAATGGTCAAGGTCACAAAAATGTCCAAGGAACGCTTTGCTTCTGAATGGACAG
GTGTCACCATATGCCTTGCTCCTAAGCCAAATTATAAACCACATAAAGACCAAAAAAATGGACTATTAGGCTTCTTTCCG
CTTATTTTTAAACAGCGAGCCCTTATATTTTATATCGTGTTAGCTTCTGTCTTGGTAACGGTCATTAATATTTCTGGTTC
ATACTATCTCCAAGGGATTTTAGACGAGTATATTCCAAATCAGCTGAAATCTACCTTAGGGATTGTATCAATTGGTCTCA
TCATTACCTATATACTCCAGCAGCTAATGAGCTTTTCTAGAGATTATCTTTTAACTGTCCTTAGCCAACGTCTTACGATT
GATGTGATCCTGTCCTATATCCGCCATATTTTCGAATTGCCGATGTCCTTTTTTGCAACACGTCGAACAGGTGAGGTAAC
CTCGCGCTTTACAGATGCTAACTCTATCATTGACGCACTCGCTTCAACCATTTTATCCCTCTTTCTAGACCTCTCTATAT
TAGCTATTGTCGGAAGTGTTCTTTTGGTGCAAAATAGCAGGCTTTTTCTGCTATCTCTGATTTCTATCCCAGTATATACC
ATTATCATATGTGCCTTTATAAAGCCGTTTGAACAAATGAATCATGATGTGATGCAAAGCAATGCCATGCTAAGCTCTGC
TATTATCGAAGATATCAACGGGATCGAAACCATAAAATCACTAACCAGTGAAGAAAACCGTTACCAAAAAATTGACAGCG
ACTTTGTGGATTACCTTGATAAGTCTTTTAAGCTTAGTAAATATACCATCTTACAAGCCACACTTAAGCAAGGAGCGCAG
CTAATTCTGAATATCATCATTCTTTGGTTTGGGGCTCAACTGGTCATTAATGGTAAAATTTCAATCGGGCAATTAATTAC
CTTTAACACACTTCTTGCCTATTTTACAACCCCTTTAGAAAATATCATTAATCTTCAAACCAAGCTCCAAGCAGCTAAGG
TTGCCAATAATCGTCTCAATGAGGTCTATCTTGTAGAGTCCGAATTTAAAGCCTCGCAAGCCTTATACGATTTATCGCTC
TTACAGGGTGACATTCAGTTTGAAGCTGTTTCCTACAGGTATGGCTTTGGCAAGGATACATTATCAGATATTACATTAAC
CATTAAGCAGGGAGCAAAAGTAACCCTTGTTGGTGTCAGCGGCTCAGGAAAAACAACCCTAGCCAAGATGCTCGTCAATT
TCTTTGAACCTTATAAGGGACGTATAACCATCAACCAAAACGATCTCAAGACCATTGATAAAAAGAATCTTCGACAATAC
ATCAACTACCTTCCACAACAAGCCTATATCTTTAATGGATCTATCTTAGAAAATCTAACCTTGGGAGCCAAGCAAGGCAT
CAGCCAGGAAGACATTCTTAACGCCTGTGAGATTGCTGACATTCGTCACGACATCGAGCAAATGCCAATGGGATACCAAA
CCGAGCTCTCTGATGGGGCTGGCTTATCTGGCGGACAAAAACAGAGAATTGCACTTGCTAGAGCATTACTAACCCAAGCT
CCTATACTAGTTCTTGATGAAGCAACCAGCGGACTTGACATACTGACAGAAAAGAAAATCATTGACCGTCTCATGAACAT
GACAGACAAAACGATTATTTTCGTTGCCCACCGGCTTAGTATCGCAGAGCGCACTGATCAGGTTGTTGTTCTTAATCAAG
GGCAAATCATTGAGACAGGCAGCCACCAGGAATTAATGAAACAAGGTGGATTTTATTACCACCTATTTAGTGAATAA

Domains

Predicted by InterproScan.

• ABC transporter transmembrane region (ABC_membrane) (169-439)

• Peptidase C39 family (Peptidase_C39) (8-143)

• ABC transporter (ABC_tran) (501-650)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	71.269	99.861	0.712
comA	Streptococcus mitis SK321	67.602	99.304	0.671
comA	Streptococcus mitis NCTC 12261	67.321	99.304	0.669
comA	Streptococcus pneumoniae Rx1	66.9	99.304	0.664
comA	Streptococcus pneumoniae D39	66.9	99.304	0.664
comA	Streptococcus pneumoniae R6	66.9	99.304	0.664
comA	Streptococcus pneumoniae TIGR4	66.62	99.304	0.662
comA	Streptococcus gordonii str. Challis substr. CH1	65.358	99.304	0.649