Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   KCL43_RS07875 Genome accession   NZ_CP073275
Coordinates   1666353..1667102 (-) Length   249 a.a.
NCBI ID   WP_042671079.1    Uniprot ID   -
Organism   Streptococcus equi subsp. zooepidemicus strain IN-6992     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1661353..1672102
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KCL43_RS07860 (KCL43_07860) - 1663309..1664666 (+) 1358 Protein_1535 bacteriocin secretion accessory protein -
  KCL43_RS07865 (KCL43_07865) - 1664766..1664900 (+) 135 WP_043030066.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  KCL43_RS07870 (KCL43_07870) - 1665019..1666353 (-) 1335 WP_165623392.1 sensor histidine kinase -
  KCL43_RS07875 (KCL43_07875) comE/blpR 1666353..1667102 (-) 750 WP_042671079.1 LytR/AlgR family response regulator transcription factor Regulator
  KCL43_RS07880 (KCL43_07880) - 1667729..1667932 (-) 204 WP_012516120.1 TmhB bacteriocin enhancer peptide -
  KCL43_RS07885 (KCL43_07885) - 1667949..1668206 (-) 258 WP_038674051.1 Blp family class II bacteriocin -
  KCL43_RS07890 (KCL43_07890) rlmD 1668527..1669894 (-) 1368 WP_165623391.1 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD -
  KCL43_RS07895 (KCL43_07895) - 1669891..1670859 (-) 969 WP_012516123.1 helix-hairpin-helix domain-containing protein -
  KCL43_RS07900 (KCL43_07900) recX 1670923..1671699 (+) 777 WP_043984249.1 recombination regulator RecX -

Sequence

Protein


Download         Length: 249 a.a.        Molecular weight: 29227.69 Da        Isoelectric Point: 8.4602

>NTDB_id=558790 KCL43_RS07875 WP_042671079.1 1666353..1667102(-) (comE/blpR) [Streptococcus equi subsp. zooepidemicus strain IN-6992]
MRVVILEDDMIQQRYLEKLIKELEVKHQLLFQGLDCFGRPHQLLSAIKKNCGQQLFFLDIEIKNEDKKGLEVARQIRQIN
PDAMIVFVTTHSEFMPLAFQYQVSALDYIDKELPHTEFVQRVETALLYAVRQNSETIAESAFYFTSRYAQVQVPFNDILY
IETSSRAHRVNLYTKKERMQFTGTLTDILKQESRFLQCHRSFLINPRNVVRVDKIERVVYFRNGSSCLIARSKMNSVLTT
IENLHRGDN

Nucleotide


Download         Length: 750 bp        

>NTDB_id=558790 KCL43_RS07875 WP_042671079.1 1666353..1667102(-) (comE/blpR) [Streptococcus equi subsp. zooepidemicus strain IN-6992]
GTGAGAGTAGTTATTTTAGAAGATGATATGATTCAGCAGAGATATTTAGAAAAGCTCATTAAAGAGCTTGAGGTTAAGCA
CCAGCTATTATTTCAAGGACTTGACTGTTTTGGAAGGCCTCATCAGCTATTAAGTGCTATCAAGAAGAACTGTGGTCAGC
AGCTATTCTTTTTAGATATTGAGATAAAAAATGAGGACAAAAAAGGGCTTGAGGTTGCTAGGCAAATTCGTCAGATAAAT
CCAGATGCGATGATTGTTTTTGTAACGACTCACTCGGAATTTATGCCCTTGGCTTTTCAGTATCAGGTATCTGCTTTGGA
CTATATCGATAAAGAGCTGCCTCACACTGAGTTTGTTCAACGGGTAGAGACTGCTTTATTATATGCTGTGCGGCAAAATA
GTGAAACGATAGCGGAAAGTGCTTTTTATTTTACATCTCGTTATGCTCAGGTACAGGTGCCTTTTAATGATATCCTGTAT
ATTGAGACATCGTCACGAGCGCATCGTGTCAATTTGTATACAAAAAAGGAGAGAATGCAATTTACAGGGACTTTGACGGA
TATTTTGAAGCAAGAGTCTCGTTTTTTGCAATGTCATCGTTCTTTTTTGATTAATCCTAGGAATGTCGTTAGGGTAGATA
AGATTGAGCGAGTGGTTTATTTTCGAAATGGCTCTAGCTGCTTAATTGCTCGTAGTAAAATGAACAGTGTTTTAACAACA
ATTGAGAACCTACATAGAGGAGATAATTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-122)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

52.61

100

0.526
  comE/comE1 Streptococcus equinus JB1

40.167

95.984

0.386