Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   KCG51_RS03155 Genome accession   NZ_CP073119
Coordinates   651369..651656 (+) Length   95 a.a.
NCBI ID   WP_036472233.1    Uniprot ID   A0A4D7WS56
Organism   Neisseria subflava strain HP0069     
Function   DNA binding (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 643151..659561 651369..651656 within 0


Gene organization within MGE regions


Location: 643151..659561
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KCG51_RS03120 (KCG51_03160) thrB 643151..644068 (-) 918 WP_250579088.1 homoserine kinase -
  KCG51_RS03125 (KCG51_03165) - 644229..645235 (+) 1007 Protein_604 IS5 family transposase -
  KCG51_RS03155 (KCG51_03195) comE 651369..651656 (+) 288 WP_036472233.1 helix-hairpin-helix domain-containing protein Machinery gene
  KCG51_RS03160 comP 651900..652172 (+) 273 WP_254342781.1 type IV pilin protein Machinery gene
  KCG51_RS03165 (KCG51_03205) - 652403..653227 (-) 825 WP_070713410.1 undecaprenyl-diphosphate phosphatase -
  KCG51_RS03170 (KCG51_03210) dsbA1 653272..653913 (-) 642 WP_250579091.1 thiol:disulfide interchange protein DsbA/DsbL Machinery gene
  KCG51_RS03175 (KCG51_03215) - 653925..655040 (-) 1116 WP_250579092.1 SPOR domain-containing protein -
  KCG51_RS03180 (KCG51_03220) - 655195..656690 (-) 1496 Protein_610 YifB family Mg chelatase-like AAA ATPase -
  KCG51_RS03185 (KCG51_03225) - 656704..657024 (-) 321 WP_003684455.1 accessory factor UbiK family protein -
  KCG51_RS03190 (KCG51_03230) metK 657134..658303 (-) 1170 WP_254342784.1 methionine adenosyltransferase -
  KCG51_RS03195 (KCG51_03235) - 658835..659032 (+) 198 WP_107858221.1 hypothetical protein -
  KCG51_RS03200 (KCG51_03240) - 659100..659561 (+) 462 WP_254342786.1 hypothetical protein -

Sequence

Protein


Download         Length: 95 a.a.        Molecular weight: 9763.42 Da        Isoelectric Point: 10.4923

>NTDB_id=558152 KCG51_RS03155 WP_036472233.1 651369..651656(+) (comE) [Neisseria subflava strain HP0069]
MKKFLFGAFAAVCAAFSLAAVNINTASSAELEALPGIGPAKAKSIVEYRQKNGAFKSVEELKNVKGIGDAVLNKLKAEAT
VSSAAPKAAQPAVKK

Nucleotide


Download         Length: 288 bp        

>NTDB_id=558152 KCG51_RS03155 WP_036472233.1 651369..651656(+) (comE) [Neisseria subflava strain HP0069]
ATGAAGAAATTTTTATTTGGTGCATTTGCCGCTGTTTGTGCAGCGTTCTCTTTGGCTGCCGTGAACATCAATACCGCGTC
TTCTGCCGAACTGGAGGCCTTGCCGGGTATCGGGCCGGCTAAGGCGAAATCGATTGTGGAATACCGTCAGAAGAATGGTG
CGTTCAAATCGGTGGAGGAGCTGAAAAACGTGAAGGGCATCGGTGATGCGGTGCTGAACAAGTTGAAGGCGGAGGCGACG
GTTTCTTCTGCCGCGCCTAAGGCCGCACAGCCTGCCGTGAAAAAATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(20-77)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A4D7WS56

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Neisseria gonorrhoeae MS11

62.626

100

0.653
  comE Neisseria gonorrhoeae MS11

62.626

100

0.653
  comE Neisseria gonorrhoeae MS11

62.626

100

0.653
  comE Neisseria gonorrhoeae MS11

62.626

100

0.653
  Cj0011c Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

54.321

85.263

0.463
  comEA Vibrio parahaemolyticus RIMD 2210633

44.186

90.526

0.4