Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   INT76_RS01710 Genome accession   NZ_CP073084
Coordinates   345528..346370 (-) Length   280 a.a.
NCBI ID   WP_212571511.1    Uniprot ID   -
Organism   Streptococcus oriscaviae strain HKU75     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 340902..351398 345528..346370 within 0


Gene organization within MGE regions


Location: 340902..351398
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  INT76_RS01695 (INT76_01695) trmFO 340902..342236 (-) 1335 WP_212571505.1 methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO -
  INT76_RS01700 (INT76_01700) - 342491..343171 (-) 681 WP_212571507.1 hypothetical protein -
  INT76_RS01705 (INT76_01705) topA 343298..345391 (-) 2094 WP_212571509.1 type I DNA topoisomerase -
  INT76_RS01710 (INT76_01710) dprA 345528..346370 (-) 843 WP_212571511.1 DNA-processing protein DprA Machinery gene
  INT76_RS01715 (INT76_01715) - 346420..347382 (-) 963 WP_212571513.1 ROK family protein -
  INT76_RS01720 (INT76_01720) - 347393..347947 (-) 555 WP_212571515.1 sugar O-acetyltransferase -
  INT76_RS01725 (INT76_01725) - 347966..348226 (-) 261 WP_212571517.1 metal-sensitive transcriptional regulator -
  INT76_RS01730 (INT76_01730) - 348335..348661 (+) 327 WP_212571519.1 rhodanese-like domain-containing protein -
  INT76_RS01735 (INT76_01735) - 348674..350326 (+) 1653 WP_212571521.1 FAD-dependent oxidoreductase -
  INT76_RS01740 (INT76_01740) - 350451..350759 (-) 309 WP_212571523.1 hypothetical protein -
  INT76_RS01750 (INT76_01750) - 350961..351398 (-) 438 WP_212571525.1 hypothetical protein -

Sequence

Protein


Download         Length: 280 a.a.        Molecular weight: 31388.20 Da        Isoelectric Point: 8.7899

>NTDB_id=557820 INT76_RS01710 WP_212571511.1 345528..346370(-) (dprA) [Streptococcus oriscaviae strain HKU75]
MNNFELFKLKKAGLTNLNINKVLAYQERYQKKLSIRNIAVVSECKNPVLFIEAYKQLDITACREEFNRYPSFSILDEVYP
LELKQIYNPPILLFYQGDLDLLSKPKLAVVGSRKASKEGSQSVQKIVKELQNRFVVVSGLARGIDTAAHMASLKSGGKTI
AVIGTGLDHYYPKENKQLQDYLSKHHLVLTEYEPSAQPKKFHFPERNRIIAGLAQGIVVAEARMRSGSLITCERALEEGR
DVFAIPGSILDGHSDGCHHLIQEGAKCITSGMDVLSDYQF

Nucleotide


Download         Length: 843 bp        

>NTDB_id=557820 INT76_RS01710 WP_212571511.1 345528..346370(-) (dprA) [Streptococcus oriscaviae strain HKU75]
ATGAATAATTTTGAACTGTTTAAATTGAAAAAAGCAGGCTTGACAAATCTCAACATCAACAAGGTTCTGGCTTATCAAGA
GCGTTATCAGAAAAAATTGAGCATAAGAAATATCGCAGTCGTTTCTGAGTGTAAGAATCCTGTTCTTTTTATCGAAGCCT
ATAAGCAGTTGGATATAACTGCTTGTCGGGAGGAGTTTAATCGCTACCCATCTTTTTCCATCTTAGATGAGGTTTATCCT
CTGGAGCTCAAGCAAATCTATAATCCACCAATCCTGTTATTTTATCAAGGTGATTTGGACTTATTGTCCAAACCAAAGTT
GGCAGTTGTCGGTTCGCGCAAGGCCAGCAAGGAAGGAAGTCAATCGGTTCAAAAGATTGTAAAAGAACTCCAAAATCGTT
TTGTGGTTGTCAGCGGTCTGGCTAGAGGGATTGACACAGCGGCCCATATGGCTAGTCTGAAAAGTGGCGGTAAAACCATT
GCGGTCATAGGAACAGGCCTAGACCATTATTATCCAAAGGAAAATAAGCAGCTCCAAGACTATCTATCAAAACACCATCT
TGTTTTGACAGAGTATGAACCGTCCGCCCAACCCAAGAAATTTCATTTTCCTGAGCGTAATCGCATCATAGCAGGGCTAG
CTCAGGGCATTGTTGTTGCGGAGGCCAGAATGCGGTCAGGCAGTCTGATTACCTGTGAGCGTGCCTTGGAAGAAGGAAGG
GATGTTTTTGCCATTCCAGGCTCTATATTGGATGGACATTCTGACGGCTGTCATCATTTGATTCAAGAGGGCGCAAAGTG
TATCACATCGGGGATGGATGTGCTTTCAGATTACCAATTTTGA

Domains

Predicted by InterproScan.

DNA processing protein A sterile alpha motif domain (SAM_DprA)

(1-59)

DNA recombination-mediator protein A (DNA_processg_A)

(74-269)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Streptococcus mutans UA159

71.071

100

0.711
  dprA/cilB/dalA Streptococcus mitis SK321

65.357

100

0.654
  dprA/cilB/dalA Streptococcus pneumoniae D39

64.643

100

0.646
  dprA/cilB/dalA Streptococcus pneumoniae R6

64.643

100

0.646
  dprA/cilB/dalA Streptococcus pneumoniae TIGR4

64.643

100

0.646
  dprA/cilB/dalA Streptococcus pneumoniae Rx1

64.643

100

0.646
  dprA/cilB/dalA Streptococcus mitis NCTC 12261

63.929

100

0.639
  dprA Lactococcus lactis subsp. cremoris KW2

57.5

100

0.575
  dprA Legionella pneumophila strain ERS1305867

38.966

100

0.404
  dprA Bacillus subtilis subsp. subtilis str. 168

47.748

79.286

0.379