Detailed information NTG0553223

Bioinformatically predicted

Overview

• Name: vicR
• Type: Regulator
• Locus tag: J7U24_RS05650
• Genome accession: NZ_CP072440
• Coordinates: 1068307..1069014 (-)
• Length: 235 a.a.
• NCBI ID: WP_011681206.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain S24730
• Function: repress comCDE expression; repress comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 1063307..1074014

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
J7U24_RS05625 (J7U24_05610)	yidA	1063658..1064467 (+)	810	WP_011226081.1	sugar-phosphatase	-
J7U24_RS05630 (J7U24_05615)	-	1064469..1065683 (+)	1215	WP_002953123.1	aminoacyltransferase	-
J7U24_RS05635 (J7U24_05620)	-	1065735..1066096 (-)	362	Protein_1068	YbaN family protein	-
J7U24_RS05640 (J7U24_05625)	vicX	1066156..1066968 (-)	813	WP_011681204.1	MBL fold metallo-hydrolase	Regulator
J7U24_RS05645 (J7U24_05630)	vicK	1066974..1068314 (-)	1341	WP_011681205.1	cell wall metabolism sensor histidine kinase VicK	Regulator
J7U24_RS05650 (J7U24_05635)	vicR	1068307..1069014 (-)	708	WP_011681206.1	response regulator YycF	Regulator
J7U24_RS05655 (J7U24_05640)	-	1069541..1070308 (+)	768	WP_011681207.1	amino acid ABC transporter ATP-binding protein	-
J7U24_RS05660 (J7U24_05645)	-	1070320..1071153 (+)	834	WP_011681208.1	transporter substrate-binding domain-containing protein	-
J7U24_RS05665 (J7U24_05650)	-	1071171..1071869 (+)	699	WP_011681209.1	amino acid ABC transporter permease	-
J7U24_RS05670 (J7U24_05655)	-	1071881..1072531 (+)	651	WP_011226088.1	amino acid ABC transporter permease	-
J7U24_RS05675 (J7U24_05660)	endA	1072603..1073484 (-)	882	WP_011681210.1	DNA/RNA non-specific endonuclease	Machinery gene
J7U24_RS05680 (J7U24_05665)	-	1073546..1073734 (-)	189	WP_011226090.1	DNA-directed RNA polymerase subunit beta	-

Sequence

Protein

• Length: 235 a.a.
• Molecular weight: 27058.98 Da
• Isoelectric Point: 5.0130

>NTDB_id=553223 J7U24_RS05650 WP_011681206.1 1068307..1069014(-) (vicR) [Streptococcus thermophilus strain S24730]
MKKILVVDDERPISDIIKFNLTKEGYEVVTAFDGREALEQFEAKKPDLVILDLMLPELDGLEVAKEIRKTSHTPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARIKAHLRRTETIETAVEESSNSGKQEISIGELVIVPDAFVAKKRGNEVEL
THREFELLFHLATHMGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMKNYD

Nucleotide

• Length: 708 bp

>NTDB_id=553223 J7U24_RS05650 WP_011681206.1 1068307..1069014(-) (vicR) [Streptococcus thermophilus strain S24730]
ATGAAAAAAATTCTAGTTGTTGATGATGAAAGACCAATCTCCGATATCATCAAGTTTAACCTTACTAAGGAGGGTTATGA
AGTGGTTACGGCCTTTGATGGGCGAGAAGCTTTGGAACAATTTGAAGCTAAAAAACCAGACTTGGTTATTCTGGACTTGA
TGTTGCCTGAACTGGATGGTTTGGAAGTTGCCAAGGAAATCCGTAAAACGAGCCACACACCGATTATCATGCTTTCAGCT
AAAGATAGTGAGTTTGATAAGGTTATCGGATTAGAAATTGGGGCAGACGACTATGTGACTAAGCCATTTTCTAACCGTGA
ATTGTTGGCACGTATTAAAGCCCACTTGCGTCGTACAGAAACGATTGAAACCGCAGTAGAAGAGAGCTCTAACTCTGGCA
AACAAGAAATTTCAATTGGTGAGTTGGTTATTGTTCCGGATGCCTTTGTTGCTAAAAAACGTGGAAACGAAGTTGAGTTG
ACCCACCGTGAATTTGAGTTACTCTTCCACTTGGCAACTCATATGGGACAAGTTATGACGCGTGAACATTTGCTTGAAAC
CGTTTGGGGCTATGACTATTTTGGGGATGTTCGTACTGTGGACGTAACGATTCGTCGTCTGCGTGAAAAAATTGAAGATA
CACCTAGCCGTCCTGAATATATCTTGACGCGTCGTGGTGTCGGTTATTACATGAAGAATTATGACTAG

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (4-113)

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (155-230)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vicR	Streptococcus mutans UA159	85.532	100	0.855
micA	Streptococcus pneumoniae Cp1015	80.258	99.149	0.796
covR	Lactococcus lactis subsp. lactis strain DGCC12653	46.32	98.298	0.455
covR	Streptococcus salivarius strain HSISS4	45.299	99.574	0.451
scnR	Streptococcus mutans UA159	38.559	100	0.387