Detailed information NTG0553224

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: J7U24_RS05675
• Genome accession: NZ_CP072440
• Coordinates: 1072603..1073484 (-)
• Length: 293 a.a.
• NCBI ID: WP_011681210.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain S24730
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1067603..1078484

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
J7U24_RS05650 (J7U24_05635)	vicR	1068307..1069014 (-)	708	WP_011681206.1	response regulator YycF	Regulator
J7U24_RS05655 (J7U24_05640)	-	1069541..1070308 (+)	768	WP_011681207.1	amino acid ABC transporter ATP-binding protein	-
J7U24_RS05660 (J7U24_05645)	-	1070320..1071153 (+)	834	WP_011681208.1	transporter substrate-binding domain-containing protein	-
J7U24_RS05665 (J7U24_05650)	-	1071171..1071869 (+)	699	WP_011681209.1	amino acid ABC transporter permease	-
J7U24_RS05670 (J7U24_05655)	-	1071881..1072531 (+)	651	WP_011226088.1	amino acid ABC transporter permease	-
J7U24_RS05675 (J7U24_05660)	endA	1072603..1073484 (-)	882	WP_011681210.1	DNA/RNA non-specific endonuclease	Machinery gene
J7U24_RS05680 (J7U24_05665)	-	1073546..1073734 (-)	189	WP_011226090.1	DNA-directed RNA polymerase subunit beta	-
J7U24_RS05685 (J7U24_05670)	murA	1073736..1075007 (-)	1272	WP_372434644.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
J7U24_RS05690 (J7U24_05675)	-	1075077..1075313 (-)	237	WP_002946959.1	DUF1146 family protein	-
J7U24_RS05695 (J7U24_05680)	galE	1075501..1076514 (-)	1014	WP_011681212.1	UDP-glucose 4-epimerase GalE	-
J7U24_RS05700 (J7U24_05685)	-	1076529..1076984 (-)	456	WP_024009932.1	DUF4832 domain-containing protein	-

Sequence

Protein

• Length: 293 a.a.
• Molecular weight: 31773.50 Da
• Isoelectric Point: 10.1789

>NTDB_id=553224 J7U24_RS05675 WP_011681210.1 1072603..1073484(-) (endA) [Streptococcus thermophilus strain S24730]
MAKRKTSLTNKQKRQLVTLIIAALIAVLGYLGTSNKLSPDNPIRQVASLVSGKSNKSIKSNGSTNSQSTPQEQLAETVMT
SSVKSQLGNSLEWNGAGAYIINRNKTNLNAKVSSQPYANNQVKTVQGQTVPTVANALLSKATRQYKNRQETGNGSTSWTP
AGWHQVQNLSGEYSHAVDRGHLLGYALIGGLKGFDASTSNPENIAVQTAWANQAYSDSSTGQNYYESLVRKALDKNKRVR
YRVTLIYEGENLIPSGTHLEAKSADGSLEFNVFVPNVQEGITLDYYSGKVTVN

Nucleotide

• Length: 882 bp

>NTDB_id=553224 J7U24_RS05675 WP_011681210.1 1072603..1073484(-) (endA) [Streptococcus thermophilus strain S24730]
ATGGCAAAAAGAAAGACATCTTTGACAAATAAACAGAAACGTCAGTTAGTCACATTAATAATAGCAGCTTTGATAGCTGT
TTTAGGTTACCTAGGAACCAGTAACAAGCTCTCGCCTGATAATCCTATCAGACAAGTAGCAAGCCTAGTTTCAGGGAAAT
CTAACAAATCCATTAAATCTAATGGTTCAACAAATAGTCAGTCTACACCACAAGAGCAGCTTGCTGAGACAGTAATGACT
AGTTCAGTCAAAAGCCAACTGGGTAATTCCTTAGAATGGAATGGAGCTGGGGCCTACATTATTAATAGAAATAAGACGAA
TCTAAATGCTAAGGTATCAAGCCAACCCTATGCTAATAACCAAGTCAAAACGGTTCAAGGACAAACTGTTCCTACAGTTG
CTAATGCCTTATTAAGTAAAGCAACTAGACAGTACAAAAATCGTCAAGAAACAGGGAATGGTTCAACCTCTTGGACACCA
GCTGGATGGCACCAGGTTCAAAATTTATCAGGAGAGTATAGCCATGCCGTAGATAGAGGCCATTTGCTAGGTTATGCACT
GATAGGTGGTTTGAAAGGATTTGATGCCTCGACTTCAAATCCAGAGAATATTGCTGTTCAAACTGCTTGGGCAAATCAAG
CATATAGCGATAGTTCTACAGGCCAAAACTATTATGAAAGCCTAGTACGAAAAGCTCTGGATAAAAACAAACGTGTTCGT
TATCGTGTGACCCTGATTTATGAAGGAGAGAATCTCATTCCATCAGGAACACATCTTGAAGCTAAGTCAGCAGACGGCTC
ACTTGAGTTTAATGTCTTTGTTCCAAATGTACAAGAGGGAATTACACTAGATTACTATTCAGGAAAAGTAACGGTGAATT
GA

Domains

Predicted by InterproScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (101-266)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	72.803	81.57	0.594
endA	Streptococcus pneumoniae D39	72.803	81.57	0.594
endA	Streptococcus pneumoniae R6	72.803	81.57	0.594
endA	Streptococcus pneumoniae TIGR4	72.803	81.57	0.594