Detailed information NTG0553202

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: J7U24_RS01430
• Genome accession: NZ_CP072440
• Coordinates: 266095..266994 (+)
• Length: 299 a.a.
• NCBI ID: WP_014607953.1
• Uniprot ID: A0AAN1ZWJ0
• Organism: Streptococcus thermophilus strain S24730
• Function: activate transcription of comX; activate transcription of comS (predicted from homology) Competence regulation

Genomic Context

Location: 261095..271994

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
J7U24_RS01410 (J7U24_01410)	trkA	262232..263581 (-)	1350	WP_024704181.1	Trk system potassium transporter TrkA	-
J7U24_RS01415 (J7U24_01415)	-	263870..264379 (+)	510	WP_014607952.1	tRNA (cytidine(34)-2'-O)-methyltransferase	-
J7U24_RS01420 (J7U24_01420)	-	264690..265247 (+)	558	WP_002949523.1	ECF transporter S component	-
J7U24_RS01425 (J7U24_01425)	-	265250..265900 (+)	651	WP_011225447.1	phosphatase PAP2 family protein	-
J7U24_RS01430 (J7U24_01430)	comR	266095..266994 (+)	900	WP_014607953.1	helix-turn-helix domain-containing protein	Regulator
J7U24_RS01435	-	267179..267895 (+)	717	Protein_242	ABC transporter transmembrane domain-containing protein	-
J7U24_RS01440	comA	267917..268126 (+)	210	WP_002946147.1	hypothetical protein	Regulator
J7U24_RS01445 (J7U24_01450)	-	268181..268749 (+)	569	Protein_244	ATP-binding cassette domain-containing protein	-
J7U24_RS01450 (J7U24_01455)	-	268857..269174 (+)	318	WP_011225454.1	DUF805 domain-containing protein	-
J7U24_RS01455	-	269137..269421 (-)	285	WP_014727318.1	hypothetical protein	-
J7U24_RS01460	-	269661..270557 (-)	897	WP_224102957.1	urease cluster protein	-
J7U24_RS01465 (J7U24_01465)	-	270962..271477 (+)	516	WP_002949547.1	AmiS/UreI family transporter	-
J7U24_RS01470 (J7U24_01470)	-	271502..271804 (+)	303	WP_002886558.1	urease subunit gamma	-

Sequence

Protein

• Length: 299 a.a.
• Molecular weight: 35289.70 Da
• Isoelectric Point: 5.0061

>NTDB_id=553202 J7U24_RS01430 WP_014607953.1 266095..266994(+) (comR) [Streptococcus thermophilus strain S24730]
MNIKDSIGLRIKTERERQQMSREVLCLDGAELTVRQLIRIEKGESLPSLDRLSYIAKRLGKSMTELLDQDNITIPDEYYE
MKNRLIKFPTYRNPDRIKSKLTLIEEVYEKFFDILPEEELLTLDILENILSFTSWEESPKVEEIYEDLFEQVKRKRKFST
NDLLVIDYYFFHLYGRKQYDKKLFERIIKRVLNQEIWTDDVYNIVLFNDLMAIAALKIFHNSFSDFLTVVDKALAVIENS
QLYSYKPSVFVLKAKYELLHKENKKEAAENYDKAIMFASVLEDSVLEESIKAGKLADGL

Nucleotide

• Length: 900 bp

>NTDB_id=553202 J7U24_RS01430 WP_014607953.1 266095..266994(+) (comR) [Streptococcus thermophilus strain S24730]
TTGAACATAAAAGACAGCATTGGACTAAGAATCAAAACTGAGCGTGAACGCCAACAGATGTCACGTGAAGTGCTATGTTT
AGATGGTGCGGAATTGACTGTTCGCCAGTTAATTCGTATTGAAAAGGGGGAGTCTCTCCCGTCTTTAGATAGATTATCGT
ATATTGCTAAACGTTTAGGAAAAAGTATGACAGAGTTATTGGATCAAGACAATATTACCATTCCTGACGAATATTATGAA
ATGAAGAATCGTTTGATTAAGTTTCCAACGTACAGAAACCCTGACAGAATAAAGTCTAAACTTACTTTGATTGAGGAAGT
CTATGAGAAATTTTTTGATATTCTTCCAGAAGAAGAATTATTAACTCTAGACATTCTCGAAAATATATTGAGTTTTACTA
GCTGGGAGGAGAGTCCAAAAGTTGAGGAGATATATGAAGACTTGTTTGAACAAGTCAAAAGGAAGAGGAAATTCTCAACT
AACGATTTATTAGTCATTGACTATTATTTCTTTCATCTTTATGGGAGAAAACAGTATGACAAAAAACTATTTGAAAGAAT
TATAAAGAGAGTATTAAATCAGGAAATTTGGACAGATGATGTTTACAATATTGTTTTATTTAATGATTTGATGGCTATTG
CTGCTTTAAAGATTTTTCACAATTCCTTCTCAGACTTCTTAACAGTTGTGGATAAAGCCTTAGCTGTCATAGAAAACTCA
CAATTATATAGCTACAAGCCTAGTGTTTTTGTACTTAAGGCTAAATATGAACTTCTGCATAAAGAAAACAAGAAAGAGGC
TGCAGAGAATTATGATAAGGCCATAATGTTTGCTTCCGTTTTGGAAGACTCGGTTTTAGAGGAAAGTATAAAGGCAGGAA
AATTGGCAGATGGTTTATAG

Domains

Predicted by InterproScan.

• Helix-turn-helix (HTH_3) (11-66)

• ComR tetratricopeptide (ComR_TPR) (75-292)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus thermophilus LMG 18311	99.666	100	0.997
comR	Streptococcus thermophilus LMD-9	98.997	100	0.99
comR	Streptococcus salivarius strain HSISS4	94.983	100	0.95
comR	Streptococcus salivarius SK126	94.314	100	0.943
comR/comR2	Streptococcus sobrinus strain NIDR 6715-7	42.14	100	0.421
comR/comR1	Streptococcus sobrinus strain NIDR 6715-7	41.806	100	0.418