Detailed information NTG0553130

Bioinformatically predicted

Overview

• Name: comYB
• Type: Machinery gene
• Locus tag: J7T69_RS09225
• Genome accession: NZ_CP072438
• Coordinates: 1781721..1782821 (-)
• Length: 366 a.a.
• NCBI ID: WP_116920398.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain S24733
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1776721..1787821

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
J7T69_RS09180	-	1777046..1777321 (-)	276	WP_011681681.1	hypothetical protein	-
J7T69_RS09185 (J7T69_09130)	-	1777333..1777530 (-)	198	WP_011681682.1	helix-turn-helix transcriptional regulator	-
J7T69_RS09190 (J7T69_09135)	-	1777779..1778972 (-)	1194	WP_014608740.1	acetate kinase	-
J7T69_RS09195 (J7T69_09140)	comYH	1779028..1779984 (-)	957	WP_011226622.1	class I SAM-dependent methyltransferase	Machinery gene
J7T69_RS09200 (J7T69_09145)	comGG	1780029..1780346 (-)	318	WP_002952035.1	competence type IV pilus minor pilin ComGG	-
J7T69_RS09205 (J7T69_09150)	comYF	1780324..1780761 (-)	438	WP_014608742.1	competence type IV pilus minor pilin ComGF	Machinery gene
J7T69_RS09210 (J7T69_09155)	comGE	1780745..1781038 (-)	294	WP_011226625.1	competence type IV pilus minor pilin ComGE	-
J7T69_RS09215 (J7T69_09160)	comYD	1781010..1781438 (-)	429	WP_011226626.1	competence type IV pilus minor pilin ComGD	Machinery gene
J7T69_RS09220 (J7T69_09165)	comYC	1781398..1781724 (-)	327	WP_002946126.1	competence type IV pilus major pilin ComGC	Machinery gene
J7T69_RS09225 (J7T69_09170)	comYB	1781721..1782821 (-)	1101	WP_116920398.1	competence type IV pilus assembly protein ComGB	Machinery gene
J7T69_RS09230 (J7T69_09175)	comGA/cglA/cilD	1782703..1783644 (-)	942	WP_014608745.1	competence type IV pilus ATPase ComGA	Machinery gene
J7T69_RS09235 (J7T69_09180)	-	1783725..1784087 (-)	363	WP_014608746.1	DUF1033 family protein	-

Sequence

Protein

• Length: 366 a.a.
• Molecular weight: 41797.91 Da
• Isoelectric Point: 10.1084

>NTDB_id=553130 J7T69_RS09225 WP_116920398.1 1781721..1782821(-) (comYB) [Streptococcus thermophilus strain S24733]
MPEKISKTIRRPTGISSWKVWLNKDVSLRGISKGKKLKISQQVKVIQLFKQLLKAGFTLTEIVAFLERSHLLKEASLSLM
KESLIRGDRLDQMLALVGFSDNIVTQISLADKHGNLLGSLTKIETYMLRMTKVRKKLMEVATYPILLLGFLILIMLGLKN
YLLPQLLEGDGKNNWAVQLVQIFPQLFFVSLCGLLVLGLILYLWVKRQSALVFYRRMAKIPFIGQTVRLYTTAYYAREWG
NLLGQGVDLLDLVALMQEQKSKLFRELGADLEEALMLGQSFPERIASHPFFTKELSLIIAYGEANARLGYELEVYAEEVW
QNFFNRLNKATTFVQPLIFVIVAVVIVMIYVAMLLPMYQNMEGMMS

Nucleotide

• Length: 1101 bp

>NTDB_id=553130 J7T69_RS09225 WP_116920398.1 1781721..1782821(-) (comYB) [Streptococcus thermophilus strain S24733]
TTGCCAGAGAAAATTTCCAAAACCATTCGTCGACCAACTGGAATCAGCAGTTGGAAGGTTTGGTTAAACAAGGATGTCTC
ACTGAGAGGGATATCCAAGGGGAAAAAATTAAAGATTAGTCAGCAAGTTAAGGTTATCCAGCTCTTCAAACAACTTTTAA
AGGCCGGTTTTACCTTAACTGAAATCGTAGCCTTTTTGGAGCGAAGTCACTTGCTGAAAGAAGCATCCTTGTCTCTTATG
AAAGAGAGTTTAATACGCGGTGATAGGTTGGATCAGATGTTAGCGTTAGTGGGGTTTTCGGACAATATTGTTACTCAGAT
TTCTCTTGCTGACAAGCACGGTAATCTTCTAGGGAGTCTAACAAAGATTGAAACCTATATGCTTCGTATGACAAAGGTTC
GCAAGAAACTCATGGAGGTGGCGACTTATCCCATACTACTTCTGGGTTTTCTGATTCTGATTATGCTAGGACTTAAAAAT
TATCTTCTACCCCAACTCTTAGAGGGTGATGGTAAGAATAATTGGGCTGTACAGTTGGTTCAAATTTTTCCCCAGCTTTT
TTTTGTGAGTTTGTGTGGACTCCTTGTGTTGGGTTTAATTCTCTATCTATGGGTGAAACGACAGTCAGCCCTTGTTTTTT
ATAGGCGAATGGCCAAAATCCCTTTTATTGGTCAGACAGTAAGGCTTTACACGACCGCCTATTATGCTAGGGAATGGGGA
AATTTATTAGGTCAAGGCGTTGATTTGCTAGATTTGGTGGCTCTTATGCAAGAGCAAAAGTCTAAACTCTTCCGTGAGCT
GGGAGCCGATTTGGAAGAAGCCCTGATGCTGGGACAGAGTTTTCCAGAACGTATTGCCAGTCATCCGTTTTTTACTAAGG
AGCTCTCACTAATTATTGCTTATGGGGAGGCCAATGCGAGGTTGGGATATGAGTTGGAAGTTTATGCCGAGGAGGTTTGG
CAAAACTTCTTTAACCGTCTTAATAAGGCAACAACCTTTGTGCAACCCCTCATTTTTGTTATTGTTGCAGTTGTGATTGT
AATGATCTATGTAGCCATGCTATTACCAATGTATCAAAATATGGAAGGAATGATGTCATGA

Domains

Predicted by InterproScan.

• Type II secretion system (T2SS), protein F (T2SSF) (236-356)

• Type II secretion system (T2SS), protein F (T2SSF) (51-164)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYB	Streptococcus mutans UA140	54.678	93.443	0.511
comYB	Streptococcus mutans UA159	54.678	93.443	0.511
comYB	Streptococcus gordonii str. Challis substr. CH1	51.17	93.443	0.478
comGB/cglB	Streptococcus mitis NCTC 12261	50.453	90.437	0.456
comGB/cglB	Streptococcus mitis SK321	49.697	90.164	0.448
comGB/cglB	Streptococcus pneumoniae Rx1	49.695	89.617	0.445
comGB/cglB	Streptococcus pneumoniae D39	49.695	89.617	0.445
comGB/cglB	Streptococcus pneumoniae R6	49.695	89.617	0.445
comGB/cglB	Streptococcus pneumoniae TIGR4	49.695	89.617	0.445
comGB	Lactococcus lactis subsp. cremoris KW2	45.758	90.164	0.413