Detailed information NTG0553129

Bioinformatically predicted

Overview

• Name: comYC
• Type: Machinery gene
• Locus tag: J7T69_RS09220
• Genome accession: NZ_CP072438
• Coordinates: 1781398..1781724 (-)
• Length: 108 a.a.
• NCBI ID: WP_002946126.1
• Uniprot ID: A0A0E2Q1B3
• Organism: Streptococcus thermophilus strain S24733
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1776398..1786724

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
J7T69_RS09175	-	1776664..1777089 (-)	426	WP_014608739.1	CPBP family intramembrane glutamic endopeptidase	-
J7T69_RS09180	-	1777046..1777321 (-)	276	WP_011681681.1	hypothetical protein	-
J7T69_RS09185 (J7T69_09130)	-	1777333..1777530 (-)	198	WP_011681682.1	helix-turn-helix transcriptional regulator	-
J7T69_RS09190 (J7T69_09135)	-	1777779..1778972 (-)	1194	WP_014608740.1	acetate kinase	-
J7T69_RS09195 (J7T69_09140)	comYH	1779028..1779984 (-)	957	WP_011226622.1	class I SAM-dependent methyltransferase	Machinery gene
J7T69_RS09200 (J7T69_09145)	comGG	1780029..1780346 (-)	318	WP_002952035.1	competence type IV pilus minor pilin ComGG	-
J7T69_RS09205 (J7T69_09150)	comYF	1780324..1780761 (-)	438	WP_014608742.1	competence type IV pilus minor pilin ComGF	Machinery gene
J7T69_RS09210 (J7T69_09155)	comGE	1780745..1781038 (-)	294	WP_011226625.1	competence type IV pilus minor pilin ComGE	-
J7T69_RS09215 (J7T69_09160)	comYD	1781010..1781438 (-)	429	WP_011226626.1	competence type IV pilus minor pilin ComGD	Machinery gene
J7T69_RS09220 (J7T69_09165)	comYC	1781398..1781724 (-)	327	WP_002946126.1	competence type IV pilus major pilin ComGC	Machinery gene
J7T69_RS09225 (J7T69_09170)	comYB	1781721..1782821 (-)	1101	WP_116920398.1	competence type IV pilus assembly protein ComGB	Machinery gene
J7T69_RS09230 (J7T69_09175)	comGA/cglA/cilD	1782703..1783644 (-)	942	WP_014608745.1	competence type IV pilus ATPase ComGA	Machinery gene
J7T69_RS09235 (J7T69_09180)	-	1783725..1784087 (-)	363	WP_014608746.1	DUF1033 family protein	-

Sequence

Protein

• Length: 108 a.a.
• Molecular weight: 11914.00 Da
• Isoelectric Point: 9.9219

>NTDB_id=553129 J7T69_RS09220 WP_002946126.1 1781398..1781724(-) (comYC) [Streptococcus thermophilus strain S24733]
MKLMLKKLNAVKLRAFTLIEMLVVLLIISILLLLFVPNLSKQKDSVKETGNAAVVKVVDSQAELYEMKNNKTASLAALVS
EGQITQKQADSYNDYYAKHGGESRSVAN

Nucleotide

• Length: 327 bp

>NTDB_id=553129 J7T69_RS09220 WP_002946126.1 1781398..1781724(-) (comYC) [Streptococcus thermophilus strain S24733]
ATGAAATTGATGTTAAAAAAATTGAATGCCGTTAAATTACGAGCCTTTACTCTGATTGAAATGCTAGTAGTACTTCTCAT
TATCAGTATTCTCCTTTTGCTCTTTGTTCCTAACTTAAGCAAGCAGAAGGATTCCGTTAAGGAAACTGGAAATGCGGCTG
TAGTCAAGGTCGTGGATTCTCAGGCAGAACTTTATGAAATGAAGAATAACAAGACAGCTAGCTTGGCAGCTCTTGTTTCA
GAAGGTCAAATTACGCAAAAACAGGCAGATTCATACAATGATTACTATGCGAAACATGGTGGTGAAAGCCGCTCAGTGGC
CAATTAG

Domains

Predicted by InterproScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (14-34)

3D structure

• AlphaFold DB: A0A0E2Q1B3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYC	Streptococcus mutans UA140	69.231	96.296	0.667
comYC	Streptococcus mutans UA159	69.231	96.296	0.667
comYC	Streptococcus gordonii str. Challis substr. CH1	63.81	97.222	0.62
comGC/cglC	Streptococcus mitis SK321	62.264	98.148	0.611
comGC/cglC	Streptococcus mitis NCTC 12261	58.333	100	0.583
comGC/cglC	Streptococcus pneumoniae D39	58.491	98.148	0.574
comGC/cglC	Streptococcus pneumoniae R6	58.491	98.148	0.574
comGC/cglC	Streptococcus pneumoniae Rx1	58.491	98.148	0.574
comGC/cglC	Streptococcus pneumoniae TIGR4	58.491	98.148	0.574
comGC	Lactococcus lactis subsp. cremoris KW2	56.604	98.148	0.556
comYC	Streptococcus suis isolate S10	60.227	81.481	0.491
comGC	Staphylococcus aureus MW2	50	72.222	0.361
comGC	Staphylococcus aureus N315	50	72.222	0.361