Detailed information NTG0553047

Bioinformatically predicted

Overview

• Name: vicR
• Type: Regulator
• Locus tag: J7U26_RS05215
• Genome accession: NZ_CP072437
• Coordinates: 1003803..1004510 (-)
• Length: 235 a.a.
• NCBI ID: WP_011681206.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain S24734
• Function: repress comCDE expression; repress comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 998803..1009510

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
J7U26_RS05190 (J7U26_05190)	yidA	999154..999963 (+)	810	WP_011226081.1	sugar-phosphatase	-
J7U26_RS05195 (J7U26_05195)	-	999965..1001179 (+)	1215	WP_002953123.1	aminoacyltransferase	-
J7U26_RS05200 (J7U26_05200)	-	1001231..1001592 (-)	362	Protein_968	YbaN family protein	-
J7U26_RS05205 (J7U26_05205)	vicX	1001652..1002464 (-)	813	WP_116920393.1	MBL fold metallo-hydrolase	Regulator
J7U26_RS05210 (J7U26_05210)	vicK	1002470..1003810 (-)	1341	WP_084828862.1	cell wall metabolism sensor histidine kinase VicK	Regulator
J7U26_RS05215 (J7U26_05215)	vicR	1003803..1004510 (-)	708	WP_011681206.1	response regulator YycF	Regulator
J7U26_RS05220 (J7U26_05220)	-	1005037..1005804 (+)	768	WP_011681207.1	amino acid ABC transporter ATP-binding protein	-
J7U26_RS05225 (J7U26_05225)	-	1005816..1006649 (+)	834	WP_116920255.1	transporter substrate-binding domain-containing protein	-
J7U26_RS05230 (J7U26_05230)	-	1006667..1007365 (+)	699	WP_014608374.1	amino acid ABC transporter permease	-
J7U26_RS05235 (J7U26_05235)	-	1007377..1008027 (+)	651	WP_014608375.1	amino acid ABC transporter permease	-
J7U26_RS05240 (J7U26_05240)	endA	1008098..1008979 (-)	882	WP_116920256.1	DNA/RNA non-specific endonuclease	Machinery gene
J7U26_RS05245 (J7U26_05245)	-	1009041..1009229 (-)	189	WP_011226090.1	DNA-directed RNA polymerase subunit beta	-

Sequence

Protein

• Length: 235 a.a.
• Molecular weight: 27058.98 Da
• Isoelectric Point: 5.0130

>NTDB_id=553047 J7U26_RS05215 WP_011681206.1 1003803..1004510(-) (vicR) [Streptococcus thermophilus strain S24734]
MKKILVVDDERPISDIIKFNLTKEGYEVVTAFDGREALEQFEAKKPDLVILDLMLPELDGLEVAKEIRKTSHTPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARIKAHLRRTETIETAVEESSNSGKQEISIGELVIVPDAFVAKKRGNEVEL
THREFELLFHLATHMGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMKNYD

Nucleotide

• Length: 708 bp

>NTDB_id=553047 J7U26_RS05215 WP_011681206.1 1003803..1004510(-) (vicR) [Streptococcus thermophilus strain S24734]
ATGAAAAAAATTCTAGTTGTTGATGATGAAAGACCAATCTCCGATATCATCAAGTTTAACCTTACTAAGGAGGGTTATGA
AGTGGTTACGGCCTTTGATGGGCGAGAAGCTTTGGAACAATTTGAAGCTAAAAAACCAGACTTGGTTATTCTGGACTTGA
TGTTGCCTGAACTGGATGGTTTGGAAGTTGCCAAGGAAATCCGTAAAACGAGCCACACACCGATTATCATGCTTTCAGCT
AAAGATAGTGAGTTTGATAAGGTTATCGGATTAGAAATTGGGGCAGACGACTATGTGACTAAGCCATTTTCTAACCGTGA
ATTGTTGGCACGTATTAAAGCCCACTTGCGTCGTACAGAAACGATTGAAACTGCAGTAGAAGAGAGCTCTAACTCTGGCA
AACAAGAAATTTCAATTGGTGAGTTGGTTATTGTTCCGGATGCCTTTGTTGCTAAAAAACGTGGAAACGAAGTTGAGTTG
ACCCACCGTGAATTTGAGTTACTCTTCCATTTGGCAACTCATATGGGACAAGTTATGACGCGTGAACATTTGCTTGAAAC
CGTTTGGGGCTATGACTATTTTGGGGATGTTCGTACTGTGGACGTAACGATTCGTCGTCTGCGTGAAAAAATTGAAGATA
CACCTAGCCGTCCTGAATATATCTTGACGCGTCGTGGTGTCGGTTATTACATGAAGAATTATGACTAG

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (4-113)

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (155-230)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vicR	Streptococcus mutans UA159	85.532	100	0.855
micA	Streptococcus pneumoniae Cp1015	80.258	99.149	0.796
covR	Lactococcus lactis subsp. lactis strain DGCC12653	46.32	98.298	0.455
covR	Streptococcus salivarius strain HSISS4	45.299	99.574	0.451
scnR	Streptococcus mutans UA159	38.559	100	0.387