Detailed information NTG0552989

Bioinformatically predicted

Overview

• Name: vicR
• Type: Regulator
• Locus tag: J7T60_RS05360
• Genome accession: NZ_CP072436
• Coordinates: 1012981..1013688 (-)
• Length: 235 a.a.
• NCBI ID: WP_011681206.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain S24735
• Function: repress comCDE expression; repress comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 1007981..1018688

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
J7T60_RS05335 (J7T60_05300)	yidA	1008332..1009141 (+)	810	WP_011226081.1	sugar-phosphatase	-
J7T60_RS05340 (J7T60_05305)	-	1009143..1010357 (+)	1215	WP_011227270.1	aminoacyltransferase	-
J7T60_RS05345 (J7T60_05310)	-	1010409..1010770 (-)	362	Protein_997	YbaN family protein	-
J7T60_RS05350 (J7T60_05315)	vicX	1010830..1011642 (-)	813	WP_011681204.1	MBL fold metallo-hydrolase	Regulator
J7T60_RS05355 (J7T60_05320)	vicK	1011648..1012988 (-)	1341	WP_011226083.1	cell wall metabolism sensor histidine kinase VicK	Regulator
J7T60_RS05360 (J7T60_05325)	vicR	1012981..1013688 (-)	708	WP_011681206.1	response regulator YycF	Regulator
J7T60_RS05365 (J7T60_05330)	-	1014215..1014982 (+)	768	WP_372433368.1	amino acid ABC transporter ATP-binding protein	-
J7T60_RS05370 (J7T60_05335)	-	1014994..1015827 (+)	834	WP_179970874.1	transporter substrate-binding domain-containing protein	-
J7T60_RS05375 (J7T60_05340)	-	1015845..1016543 (+)	699	WP_065973256.1	amino acid ABC transporter permease	-
J7T60_RS05380 (J7T60_05345)	-	1016555..1017205 (+)	651	WP_011226088.1	amino acid ABC transporter permease	-
J7T60_RS05385 (J7T60_05350)	endA	1017276..1018157 (-)	882	WP_372433369.1	DNA/RNA non-specific endonuclease	Machinery gene
J7T60_RS05390 (J7T60_05355)	-	1018219..1018407 (-)	189	WP_011226090.1	DNA-directed RNA polymerase subunit beta	-

Sequence

Protein

• Length: 235 a.a.
• Molecular weight: 27058.98 Da
• Isoelectric Point: 5.0130

>NTDB_id=552989 J7T60_RS05360 WP_011681206.1 1012981..1013688(-) (vicR) [Streptococcus thermophilus strain S24735]
MKKILVVDDERPISDIIKFNLTKEGYEVVTAFDGREALEQFEAKKPDLVILDLMLPELDGLEVAKEIRKTSHTPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARIKAHLRRTETIETAVEESSNSGKQEISIGELVIVPDAFVAKKRGNEVEL
THREFELLFHLATHMGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMKNYD

Nucleotide

• Length: 708 bp

>NTDB_id=552989 J7T60_RS05360 WP_011681206.1 1012981..1013688(-) (vicR) [Streptococcus thermophilus strain S24735]
ATGAAAAAAATTCTAGTTGTTGATGATGAAAGACCAATCTCCGATATCATCAAGTTTAACCTTACTAAGGAGGGTTATGA
AGTGGTTACGGCCTTTGATGGGCGAGAAGCTTTGGAACAATTTGAAGCTAAAAAACCAGACTTGGTTATTCTGGACTTGA
TGTTGCCTGAACTGGATGGTTTGGAAGTTGCCAAGGAAATCCGTAAAACGAGCCACACACCGATTATCATGCTTTCAGCT
AAAGATAGTGAGTTTGATAAGGTTATCGGATTAGAAATTGGGGCAGACGACTATGTGACTAAGCCATTTTCTAACCGTGA
ATTGTTGGCACGTATTAAAGCCCACTTGCGTCGTACAGAAACGATTGAAACTGCAGTAGAAGAGAGCTCTAACTCTGGCA
AACAAGAAATTTCAATTGGTGAGTTGGTTATTGTTCCGGATGCCTTTGTTGCTAAAAAACGTGGAAACGAAGTTGAGTTG
ACCCACCGTGAATTTGAGTTACTCTTCCATTTGGCAACTCATATGGGACAAGTTATGACGCGAGAACATTTGCTTGAAAC
CGTTTGGGGCTATGACTATTTTGGGGATGTTCGTACTGTGGACGTAACGATTCGTCGTCTGCGTGAAAAAATTGAAGATA
CACCTAGCCGTCCTGAATATATCTTGACGCGTCGTGGTGTCGGTTATTACATGAAGAATTATGACTAG

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (4-113)

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (155-230)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vicR	Streptococcus mutans UA159	85.532	100	0.855
micA	Streptococcus pneumoniae Cp1015	80.258	99.149	0.796
covR	Lactococcus lactis subsp. lactis strain DGCC12653	46.32	98.298	0.455
covR	Streptococcus salivarius strain HSISS4	45.299	99.574	0.451
scnR	Streptococcus mutans UA159	38.559	100	0.387