Detailed information NTG0552990

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: J7T60_RS05385
• Genome accession: NZ_CP072436
• Coordinates: 1017276..1018157 (-)
• Length: 293 a.a.
• NCBI ID: WP_372433369.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain S24735
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1012276..1023157

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
J7T60_RS05360 (J7T60_05325)	vicR	1012981..1013688 (-)	708	WP_011681206.1	response regulator YycF	Regulator
J7T60_RS05365 (J7T60_05330)	-	1014215..1014982 (+)	768	WP_372433368.1	amino acid ABC transporter ATP-binding protein	-
J7T60_RS05370 (J7T60_05335)	-	1014994..1015827 (+)	834	WP_179970874.1	transporter substrate-binding domain-containing protein	-
J7T60_RS05375 (J7T60_05340)	-	1015845..1016543 (+)	699	WP_065973256.1	amino acid ABC transporter permease	-
J7T60_RS05380 (J7T60_05345)	-	1016555..1017205 (+)	651	WP_011226088.1	amino acid ABC transporter permease	-
J7T60_RS05385 (J7T60_05350)	endA	1017276..1018157 (-)	882	WP_372433369.1	DNA/RNA non-specific endonuclease	Machinery gene
J7T60_RS05390 (J7T60_05355)	-	1018219..1018407 (-)	189	WP_011226090.1	DNA-directed RNA polymerase subunit beta	-
J7T60_RS05395 (J7T60_05360)	murA	1018409..1019680 (-)	1272	WP_164178134.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
J7T60_RS05400 (J7T60_05365)	-	1019750..1019986 (-)	237	WP_002946959.1	DUF1146 family protein	-
J7T60_RS05405 (J7T60_05370)	galE	1020174..1021187 (-)	1014	WP_179970875.1	UDP-glucose 4-epimerase GalE	-
J7T60_RS05410 (J7T60_05375)	-	1021202..1021657 (-)	456	WP_179970876.1	DUF4832 domain-containing protein	-

Sequence

Protein

• Length: 293 a.a.
• Molecular weight: 31788.52 Da
• Isoelectric Point: 10.2456

>NTDB_id=552990 J7T60_RS05385 WP_372433369.1 1017276..1018157(-) (endA) [Streptococcus thermophilus strain S24735]
MAKRKTSLTNKQKRQLVTLIIAALIAVLGYLGTSNKLSPDNPIRQVASLVSGKSNKSIKSNGSTNSQSTPQEQLSETVMT
SSVKSQLGNSLEWNGAGAYIINRNKTNLNAKVSSQPYANNQVKTVQGQTVPTVANALLSKATRQYKNRQETGNGSTSWTP
AGWHQVQNLSGEYSHAVDRGHLLGYALIGGLKGFDASTSNPENIAVQTAWANQAYSNSSTGQNYYESLVRKALDKNKRVR
YRVTLIYEGENLIPSGTHLEAKSADGSLEFNVFVPNVQEGITLDYYSGKVTVN

Nucleotide

• Length: 882 bp

>NTDB_id=552990 J7T60_RS05385 WP_372433369.1 1017276..1018157(-) (endA) [Streptococcus thermophilus strain S24735]
ATGGCAAAAAGAAAGACATCTTTGACAAATAAACAGAAACGTCAGTTAGTCACATTAATAATAGCAGCTTTAATAGCTGT
TTTAGGTTACCTAGGAACCAGTAACAAGCTCTCGCCTGATAATCCTATCAGACAAGTAGCAAGCCTAGTTTCAGGGAAAT
CTAACAAATCCATTAAATCTAATGGTTCAACAAATAGTCAGTCTACACCACAAGAGCAGCTTTCTGAGACAGTAATGACT
AGTTCAGTCAAAAGCCAACTGGGTAATTCCTTGGAATGGAATGGAGCTGGGGCCTACATTATTAATAGAAATAAGACGAA
TCTAAATGCTAAGGTATCAAGCCAACCCTATGCTAATAACCAAGTCAAAACGGTTCAAGGACAAACTGTTCCTACAGTTG
CTAATGCCTTATTAAGTAAAGCAACTAGACAGTACAAAAATCGTCAAGAAACAGGGAATGGTTCAACCTCTTGGACACCA
GCTGGATGGCACCAGGTTCAAAATTTATCAGGAGAGTATAGCCATGCCGTAGATAGAGGTCATTTGCTAGGTTATGCACT
GATAGGTGGTTTGAAAGGATTTGACGCCTCGACTTCAAATCCAGAGAATATTGCTGTTCAAACTGCTTGGGCAAATCAAG
CATATAGCAATAGTTCTACAGGCCAAAACTATTATGAAAGCCTAGTACGAAAAGCTCTGGATAAAAACAAACGTGTTCGT
TATCGTGTGACCCTGATTTATGAAGGAGAGAATCTCATTCCATCAGGAACACATCTTGAAGCTAAGTCAGCAGACGGCTC
ACTTGAGTTTAATGTCTTTGTTCCAAATGTACAAGAGGGAATTACACTAGATTACTATTCAGGAAAAGTAACGGTGAATT
GA

Domains

Predicted by InterproScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (101-266)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	72.385	81.57	0.59
endA	Streptococcus pneumoniae D39	72.385	81.57	0.59
endA	Streptococcus pneumoniae R6	72.385	81.57	0.59
endA	Streptococcus pneumoniae TIGR4	72.385	81.57	0.59